Michael Gütschow

发表

Integrating Structure‐ and Ligand‐Based Virtual Screening: Comparison of Individual, Parallel, and Fused Molecular Docking and Similarity Search Calculations on Multiple Targets

Hanna Geppert, Jürgen Bajorath, Lu Tan, 2008, ChemMedChem.

Systematic Identification and Classification of Three-Dimensional Activity Cliffs

Jürgen Bajorath, Ye Hu, Norbert Furtmann, 2012, J. Chem. Inf. Model..

Privileged Structural Motif Detection and Analysis Using Generative Topographic Maps

Jürgen Bajorath, Alexandre Varnek, Dragos Horvath, 2017, J. Chem. Inf. Model..

New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science: Joint Virtual Special Issue by Journal of Medicinal Chemistry, ACS Medicinal Chemistry Letters, and ACS Pharmacology & Translational Science

Craig W. Lindsley, Dennis Liotta, Michael Gütschow, 2021, ACS Pharmacology & Translational Science.

Dual targeting of adenosine A(2A) receptors and monoamine oxidase B by 4H-3,1-benzothiazin-4-ones.

Sonja Hinz, Michael Gütschow, C. Müller, 2013, Journal of medicinal chemistry.

Matriptase-2 (TMPRSS6) is directly up-regulated by hypoxia inducible factor-1: identification of a hypoxia-responsive element in the TMPRSS6 promoter region

Michael Gütschow, M. Gütschow, M. Stirnberg, 2012, Biological chemistry.

Identification of Interaction Hot Spots in Structures of Drug Targets on the Basis of Three‐Dimensional Activity Cliff Information

Jürgen Bajorath, Ye Hu, Norbert Furtmann, 2015, Chemical biology & drug design.

Promiscuous Ligands from Experimentally Determined Structures, Binding Conformations, and Protein Family-Dependent Interaction Hotspots

Jürgen Bajorath, Michael Gütschow, Erik Gilberg, 2019, ACS omega.

Identification and analysis of the currently available high-confidence three-dimensional activity cliffs

Jürgen Bajorath, Ye Hu, Norbert Furtmann, 2015 .

A biased ligand for OXE-R uncouples Gα and Gβγ signaling within a heterotrimer.

Leonardo Pardo, Evi Kostenis, Michael Gütschow, 2012, Nature chemical biology.

Currently available 3D activity cliffs and 2D-analogs of 3D-cliff compounds

Jürgen Bajorath, Ye Hu, Norbert Furtmann, 2015 .

Hit Expansion through Computational Selectivity Searching

Jürgen Bajorath, José Batista, Dagmar Stumpfe, 2009, ChemMedChem.

Structural characterization of two salts derived from tetrafluorophthalic acid and isopropylamine

Martin Nieger, Michael Gütschow, M. Gütschow, 2008 .

Evaluation of dipeptide nitriles as inhibitors of rhodesain, a major cysteine protease of Trypanosoma brucei.

Michael Gütschow, Tanja Schirmeister, M. Gütschow, 2017, Bioorganic & medicinal chemistry letters.