J B Houston

发表

Effect of various alcohols on intestinal net water flux and theophylline absorption in rats.

G Levy, J B Houston, G. Levy, 1975, Journal of pharmaceutical sciences.

The Integrated Use of Alternative Methods in Toxicological Risk Evaluation

J B Houston, M D Barratt, B J Blaauboer, 1999, Alternatives to laboratory animals : ATLA.

The Validation of Computational Prediction Techniques

A P Worth, J B Houston, M D Barratt, 1998, Alternatives to laboratory animals : ATLA.

Microsomal prediction of in vivo clearance and associated interindividual variability of six benzodiazepines in humans

J B Houston, A. Galetin, J. Houston, 2005, Xenobiotica; the fate of foreign compounds in biological systems.

Methodological uncertainty in quantitative prediction of human hepatic clearance from in vitro experimental systems.

J B Houston, J. Houston, D. Hallifax, 2009, Current drug metabolism.

Prediction of hepatic clearance from microsomes, hepatocytes, and liver slices.

J B Houston, J. Houston, D. Carlile, 1997, Drug metabolism reviews.

Scaling factors to relate drug metabolic clearance in hepatic microsomes, isolated hepatocytes, and the intact liver: studies with induced livers involving diazepam.

J B Houston, J. Houston, K. Zomorodi, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance.

J B Houston, J. Houston, 1994, Biochemical pharmacology.

In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model.

J B Houston, J. Houston, Kathryn E. Kenworthy, 2000, Drug metabolism and disposition: the biological fate of chemicals.

Pharmacokinetics in Early Drug Research

J B Houston, D A Smith, J H Fentem, 1997, Alternatives to laboratory animals : ATLA.

Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

J B Houston, J. Houston, D. Hallifax, 2017, Drug Metabolism and Disposition.

CYP3A4 drug interactions: correlation of 10 in vitro probe substrates.

J B Houston, J. Houston, J. Bloomer, 1999, British journal of clinical pharmacology.

Optimizing drug development: strategies to assess drug metabolism/transporter interaction potential--towards a consensus.

J B Houston, Shiew-Mei Huang, J. Houston, 2001, British journal of clinical pharmacology.

An Integrated Approach to the Prediction of Systemic Toxicity using Computer-based Biokinetic Models and Biological In vitro Test Methods: Overview of a Prevalidation Study Based on the ECITTS Project.

J B Houston, B J Blaauboer, J. DeJongh, 1999, Toxicology in vitro : an international journal published in association with BIBRA.

Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity.

J B Houston, J. Houston, N. Hakooz, 1999, Drug metabolism and disposition: the biological fate of chemicals.

Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells

J B Houston, J. Houston, N. Randolph, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

In vitro human tissue models in risk assessment: report of a consensus-building workshop.

J B Houston, G. L. Kedderis, K Krishnan, 2001, Toxicological sciences : an official journal of the Society of Toxicology.