Christopher J. Chang

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Grand Challenges in Chemistry for 2016 and Beyond

Carolyn R. Bertozzi, Dongyuan Zhao, Christopher J. Chang, 2016, ACS central science.

Christopher J. Chang, 2016, ACS central science.

Increase of sodium delivery stimulates the mitochondrial respiratory chain H2O2 production in rat renal medullary thick ascending limb.

Christopher J. Chang, S. Ito, Yusuke Ohsaki, 2012, American journal of physiology. Renal physiology.

Nanowire-bacteria hybrids for unassisted solar carbon dioxide fixation to value-added chemicals.

Christopher J. Chang, Michelle C. Y. Chang, P. Yang, 2015, Nano letters.

Copper signaling in the brain and beyond

Christopher J. Chang, Cheri M Ackerman, C. Ackerman, 2017, The Journal of Biological Chemistry.

Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging

Christopher J. Chang, D. Domaille, Emily L. Que, 2008 .

In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter

Carolyn R. Bertozzi, Christopher J. Chang, C. Bertozzi, 2010, Proceedings of the National Academy of Sciences.

Improvement of Human Keratinocyte Migration by a Redox Active Bioelectric Dressing

Savita Khanna, Sashwati Roy, Chandan K. Sen, 2014, PloS one.

Unraveling the biological roles of reactive oxygen species.

Linda Partridge, Thomas Nyström, Christopher J. Chang, 2011, Cell metabolism.

Activity-Based Sensing: A Synthetic Methods Approach for Selective Molecular Imaging and Beyond.

Christopher J. Chang, Kevin J. Bruemmer, Steven W. M. Crossley, 2020, Angewandte Chemie.

Reaction-based fluorescent probes for selective imaging of hydrogen sulfide in living cells.

Christopher J. Chang, A. Lippert, Alexander R. Lippert, 2011, Journal of the American Chemical Society.

Fluorescent probes for sensing and imaging biological hydrogen sulfide.

Christopher J. Chang, Vivian S. Lin, Christopher J. Chang, 2012, Current opinion in chemical biology.

A reaction-based fluorescent probe for selective imaging of carbon monoxide in living cells using a palladium-mediated carbonylation.

Christopher J. Chang, A. Lippert, Alexander R. Lippert, 2012, Journal of the American Chemical Society.

Increasing extracellular H2O2 produces a bi-phasic response in intracellular H2O2, with peroxiredoxin hyperoxidation only triggered once the cellular H2O2-buffering capacity is overwhelmed

Christopher J. Chang, J. Bähler, E. Veal, 2016, Free radical biology & medicine.

Chemistry and biology of reactive oxygen species in signaling or stress responses.

Bryan C Dickinson, Christopher J. Chang, Christopher J Chang, 2011, Nature chemical biology.

A dendrimer-based platform for simultaneous dual fluorescence imaging of hydrogen peroxide and pH gradients produced in living cells

Christopher J. Chang, Duangkhae Srikun, Aaron E. Albers, 2011 .

Boronate-based fluorescent probes for imaging cellular hydrogen peroxide.

Evan W. Miller, Christopher J. Chang, Ehud Y Isacoff, 2005, Journal of the American Chemical Society.

A tandem activity-based sensing and labeling strategy enables imaging of transcellular hydrogen peroxide signaling

Christopher J. Chang, R. Swanson, H. Iwashita, 2021, Proceedings of the National Academy of Sciences.

Preparation and use of MitoPY1 for imaging hydrogen peroxide in mitochondria of live cells

Christopher J. Chang, B. Dickinson, Vivian S. Lin, 2013, Nature Protocols.

Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling.

Evan W. Miller, Christopher J. Chang, Christopher J Chang, 2007, Current opinion in chemical biology.

Molecular imaging of hydrogen peroxide produced for cell signaling

Evan W. Miller, Christopher J. Chang, Ehud Y. Isacoff, 2007 .

Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems.

Wei Chen, Ming Xian, Christopher J. Chang, 2015, Chemical Society reviews.

Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis

Andrea Ballabio, Christopher J. Chang, Simona Iacobacci, 2014, Developmental cell.

Hybrid bioinorganic approach to solar-to-chemical conversion

Yi Yu, Yujie Sun, Joaquin Resasco, 2015, Proceedings of the National Academy of Sciences.

N2O activation and oxidation reactivity from a non-heme iron pyrrole platform.

Christopher J. Chang, W. Harman, Christopher J. Chang, 2007, Journal of the American Chemical Society.

Electrocatalytic reduction of protons to hydrogen by a water-compatible cobalt polypyridyl platform.

Christopher J. Chang, W. Harman, W. Harman, 2010, Chemical communications.

Multimodal LA-ICP-MS and nanoSIMS imaging enables copper mapping within photoreceptor megamitochondria in a zebrafish model of Menkes disease.

Christopher J. Chang, Cheri M Ackerman, P. Weber, 2018, Metallomics : integrated biometal science.

A targetable fluorescent sensor reveals that copper-deficient SCO1 and SCO2 patient cells prioritize mitochondrial copper homeostasis.

Christopher J. Chang, D. Winge, S. C. Leary, 2011, Journal of the American Chemical Society.

An Aza-Cope Reactivity-Based Fluorescent Probe for Imaging Formaldehyde in Living Cells.

Christopher J. Chang, T. Brewer, Christopher J. Chang, 2015, Journal of the American Chemical Society.

Bioinspiration in light harvesting and catalysis

Christopher J. Chang, Andrew H. Proppe, A. Vojvodić, 2020, Nature Reviews Materials.

A fluorescent sensor for imaging reversible redox cycles in living cells.

Evan W. Miller, Christopher J. Chang, S. Bian, 2007, Journal of the American Chemical Society.

medullary thick ascending limb production in rat renal 2 O 2 respiratory chain H Increase of sodium delivery stimulates the mitochondrial

Christopher J. Chang, S. Ito, Yusuke Ohsaki, 2016 .

Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates

Christopher J. Chang, Joel D. W. Toh, Kevin J. Bruemmer, 2020, Proceedings of the National Academy of Sciences.

A FRET-based approach to ratiometric fluorescence detection of hydrogen peroxide.

Christopher J. Chang, Aaron E. Albers, Voytek Okreglak, 2006, Journal of the American Chemical Society.

Supramolecular Tuning Enables Selective Oxygen Reduction Catalyzed by Cobalt Porphyrins for Direct Electrosynthesis of Hydrogen Peroxide.

Christopher J. Chang, Kimoon Kim, B. P. Benke, 2020, Angewandte Chemie.

Supramolecular Tuning Enables Selective Oxygen Reduction Catalyzed by Cobalt Porphyrins for Direct Electrosynthesis of Hydrogen Peroxide

Christopher J. Chang, Kimoon Kim, B. P. Benke, 2020, Angewandte Chemie.

A smart magnetic resonance contrast agent for selective copper sensing.

Christopher J. Chang, E. Que, Christopher J. Chang, 2006, Journal of the American Chemical Society.

Lysosomal SLC46A3 modulates hepatic cytosolic copper homeostasis

Christopher J. Chang, F. Gonzalez, Jung-Hwan Kim, 2021, Nature communications.

Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas.

Christopher J. Chang, S. Merchant, T. Stemmler, 2015, Nature chemical biology.

Proton-coupled electron transfer: a unifying mechanism for biological charge transport, amino acid radical initiation and propagation, and bond making/breaking reactions of water and oxygen.

Christopher J. Chang, Michelle C. Y. Chang, D. Nocera, 2004, Biochimica et biophysica acta.

A molecular molybdenum-oxo catalyst for generating hydrogen from water

Christopher J. Chang, J. Long, H. Karunadasa, 2010, Nature.

Endogenous hydrogen peroxide production in the epithelium of the developing embryonic lens

Christopher J. Chang, B. Dickinson, A. S. Menko, 2014, Molecular vision.

Slow magnetic relaxation in a high-spin iron(II) complex.

Christopher J. Chang, W. Harman, J. Long, 2010, Journal of the American Chemical Society.

Slow magnetic relaxation in a pseudotetrahedral cobalt(II) complex with easy-plane anisotropy.

Christopher J. Chang, Joseph M. Zadrozny, J. Long, 2012, Chemical communications.

A seven-coordinate iron platform and its oxo and nitrene reactivity

Christopher J. Chang, Han Sen Soo, M. Sougrati, 2011 .

A bright and specific fluorescent sensor for mercury in water, cells, and tissue.

Evan W. Miller, Christopher J. Chang, Sungho Yoon, 2007, Angewandte Chemie.

Inorganic Chemistry Approaches to Activity-Based Sensing: From Metal Sensors to Bioorthogonal Metal Chemistry.

Christopher J. Chang, Shang Jia, D. Iovan, 2019, Inorganic chemistry.

Chemical biology: Ions illuminated

Christopher J. Chang, Christopher J. Chang, 2007, Nature.

Responsive Magnetic Resonance Imaging Contrast Agents as Chemical Sensors for Metals in Biology and Medicine

Christopher J. Chang, E. Que, 2010 .

Supramolecular Porphyrin Cages Assembled at Molecular–Materials Interfaces for Electrocatalytic CO Reduction

Christopher J. Chang, Jeffrey S Derrick, Yi-sheng Liu, 2017, ACS central science.

Title Supramolecular Porphyrin Cages Assembled at Molecular-Materials Interfaces for Electrocatalytic CO Reduction Permalink

Christopher J. Chang, Yi-sheng Liu, Wei Liu, 2017 .

Consistent inclusion of continuum solvation in energy decomposition analysis: theory and application to molecular CO2 reduction catalysts

Christopher J. Chang, Jeffrey S Derrick, M. Head‐Gordon, 2020, Chemical science.

Visualizing ascorbate-triggered release of labile copper within living cells using a ratiometric fluorescent sensor.

Christopher J. Chang, D. Domaille, Li Zeng, 2010, Journal of the American Chemical Society.

An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells

Christopher J. Chang, N. Yuki, B. Dickinson, 2016, Neurobiology of Disease.

A nuclear-localized fluorescent hydrogen peroxide probe for monitoring sirtuin-mediated oxidative stress responses in vivo.

Christopher J. Chang, B. Dickinson, Z. Chang, 2011, Chemistry & biology.

A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc.

Christopher J. Chang, Elizabeth M. Nolan, S. Lippard, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Targeted proton delivery in the catalyzed reduction of oxygen to water by bimetallic pacman porphyrins.

Christopher J. Chang, D. Nocera, F. Anson, 2004, Journal of the American Chemical Society.

Bioinspired Thiophosphorodichloridate Reagents for Chemoselective Histidine Bioconjugation.

Christopher J. Chang, Shang Jia, Dan He, 2018, Journal of the American Chemical Society.

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Christopher J. Chang, A. Vazquez, Lee Mulderrig, 2017, Nature.

A reactivity-based probe of the intracellular labile ferrous iron pool

Christopher J. Chang, A. Renslo, Shaun D. Fontaine, 2016, Nature chemical biology.

A Boronate-Caged [18F]FLT Probe for Hydrogen Peroxide Detection Using Positron Emission Tomography

Christopher J. Chang, H. VanBrocklin, K. Keshari, 2014, Journal of the American Chemical Society.

Reactive oxygen species-induced actin glutathionylation controls actin dynamics in neutrophils.

Christopher J. Chang, Y. Ho, K. Ye, 2012, Immunity.

A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation.

Christopher J. Chang, Shang Jia, F. Toste, 2019, Journal of the American Chemical Society.

Zinc-secreting Paneth Cells Studied by ZP Fluorescence

Christopher J. Chang, S. Lippard, C. Frederickson, 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis

Christopher J. Chang, Allegra T. Aron, H. Bayır, 2020, Hepatology.

An Integrated Imaging Approach to the Study of Oxidative Stress Generation by Mitochondrial Dysfunction in Living Cells

Evan W. Miller, Christopher J. Chang, T. P. Hofer, 2010, Environmental health perspectives.

Metal-polypyridyl catalysts for electro- and photochemical reduction of water to hydrogen.

Christopher J. Chang, J. Long, Teera Chantarojsiri, 2015, Accounts of chemical research.

Tuning Second Coordination Sphere Interactions in Polypyridyl-Iron Complexes to Achieve Selective Electrocatalytic Reduction of Carbon Dioxide to Carbon Monoxide.

Christopher J. Chang, J. Long, A. King, 2019, Inorganic chemistry.

Activity-Based Sensing with a Metal-Directed Acyl Imidazole Strategy Reveals Cell Type-Dependent Pools of Labile Brain Copper.

Evan W. Miller, Christopher J. Chang, I. Hamachi, 2020, Journal of the American Chemical Society.

A Supramolecular Porous Organic Cage Platform Promotes Electrochemical Hydrogen Evolution from Water Catalyzed by Cobalt Porphyrins

Christopher J. Chang, Kimoon Kim, B. P. Benke, 2021, ChemElectroChem.

Towards a comprehensive understanding of visible-light photogeneration of hydrogen from water using cobalt(ii) polypyridyl catalysts

Christopher J. Chang, Rony S. Khnayzer, F. Castellano, 2014 .

Synthesis and Characterization of a Tetrapodal NO4(4-) Ligand and Its Transition Metal Complexes.

Christopher J. Chang, Katie R. Meihaus, J. Long, 2016, Inorganic chemistry.

A Molecular Surface Functionalization Approach to Tuning Nanoparticle Electrocatalysts for Carbon Dioxide Reduction.

Christopher J. Chang, P. Yang, J. Reimer, 2016, Journal of the American Chemical Society.

Iron detection and remediation with a functionalized porous polymer applied to environmental water samples

Christopher J. Chang, Cheri M Ackerman, Mercedes K. Taylor, 2019, Chemical science.

Ligand-Directed Approach to Activity-Based Sensing: Developing Palladacycle Fluorescent Probes That Enable Endogenous Carbon Monoxide Detection.

Christopher J. Chang, T. Brewer, M. Saitoe, 2020, Journal of the American Chemical Society.

Copper-responsive magnetic resonance imaging contrast agents.

Suzanne L Baker, Christopher J. Chang, Eliana Gianolio, 2009, Journal of the American Chemical Society.

Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling

Evan W. Miller, Bryan C Dickinson, Christopher J. Chang, 2010, Proceedings of the National Academy of Sciences.

A puromycin-dependent activity-based sensing probe for histochemical staining of hydrogen peroxide in cells and animal tissues

Christopher J. Chang, C. Chung, M. Messina, 2022, Nature Protocols.

Reticular Electronic Tuning of Porphyrin Active Sites in Covalent Organic Frameworks for Electrocatalytic Carbon Dioxide Reduction.

Christopher J. Chang, Chenhui Zhu, O. Yaghi, 2018, Journal of the American Chemical Society.

In vivo bioluminescence imaging of labile iron accumulation in a murine model of Acinetobacter baumannii infection

Marie C. Heffern, Christopher J. Chang, Allegra T. Aron, 2017, Proceedings of the National Academy of Sciences.

A red-emitting naphthofluorescein-based fluorescent probe for selective detection of hydrogen peroxide in living cells.

Evan W. Miller, Christopher J. Chang, B. Dickinson, 2008, Bioorganic & medicinal chemistry letters.

Chelating N-Heterocyclic Carbene Ligands Enable Tuning of Electrocatalytic CO2 Reduction to Formate and Carbon Monoxide: Surface Organometallic Chemistry.

Christopher J. Chang, Jeffrey S Derrick, C. Copéret, 2018, Angewandte Chemie.

Bacterial Killing by Dry Metallic Copper Surfaces

Christian G Elowsky, Christopher J. Chang, D. Quaranta, 2010, Applied and Environmental Microbiology.

Templating Bicarbonate in the Second Coordination Sphere Enhances Electrochemical CO2 Reduction Catalyzed by Iron Porphyrins.

Christopher J. Chang, Jeffrey S Derrick, M. Head‐Gordon, 2022, Journal of the American Chemical Society.

Deciphering Distinct Overpotential-Dependent Pathways for Electrochemical CO2 Reduction Catalyzed by an Iron-Terpyridine Complex.

Christopher J. Chang, Jeffrey S Derrick, M. Head‐Gordon, 2022, Inorganic chemistry.

An NADH-Inspired Redox Mediator Strategy to Promote Second-Sphere Electron and Proton Transfer for Cooperative Electrochemical CO2 Reduction Catalyzed by Iron Porphyrin.

Christopher J. Chang, Peter T. Smith, Sophia Weng, 2020, Inorganic chemistry.

Iron Porphyrins Embedded into a Supramolecular Porous Organic Cage for Electrochemical CO2 Reduction in Water.

Christopher J. Chang, Kimoon Kim, Z. Cao, 2018, Angewandte Chemie.

Urea-Based Multipoint Hydrogen-Bond Donor Additive Promotes Electrochemical CO2 Reduction Catalyzed by Nickel Cyclam

Christopher J. Chang, Eva M. Nichols, Christopher J. Chang, 2018, Organometallics.

Activity-based sensing fluorescent probes for iron in biological systems.

Christopher J. Chang, Allegra T. Aron, A. G. Reeves, 2018, Current opinion in chemical biology.

A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent.

Christopher J. Chang, J. Kurhanewicz, A. Lippert, 2011, Journal of the American Chemical Society.