N. S. Laursen

发表

Structure of complement C5 in complex with the C-terminal beta-grasp domain of SSL7

Edzard Spillner, N. S. Laursen, N. Gordon, 2009 .

A stable trimeric influenza hemagglutinin stem as a broadly protective immunogen

Adrian Apetri, Liesbeth Dekking, Andrew B. Ward, 2015, Science.

Isolation and Characterization of Nanobodies against a Zinc-Transporting P-Type ATPase

N. S. Laursen, P. Gourdon, K. Andersen, 2018, Antibodies.

Functional and Structural Characterization of a Potent C1q Inhibitor Targeting the Classical Pathway of the Complement System

N. S. Laursen, S. Thiel, A. Hansen, 2020, Frontiers in Immunology.

Introduction of an Aldehyde Handle on Nanobodies by Affinity-Guided Labeling.

N. S. Laursen, J. Kjems, K. Gothelf, 2020, Bioconjugate chemistry.

Purification of Human Complement Component C4 and Sample Preparation for Structural Biology Applications.

N. S. Laursen, A. Zarantonello, S. Mortensen, 2021, Methods in molecular biology.

A C3-specific nanobody that blocks all three activation pathways in the human and murine complement system

N. S. Laursen, S. Thiel, A. Hansen, 2020, The Journal of Biological Chemistry.

A Complement C3–Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity

N. S. Laursen, S. Thiel, A. Hansen, 2020, The Journal of Immunology.

A potent complement factor C3–specific nanobody inhibiting multiple functions in the alternative pathway of human and murine complement

N. S. Laursen, S. Thiel, J. Jensen, 2018, The Journal of Biological Chemistry.

Structural insights into the function-modulating effects of nanobody binding to the integrin receptor αMβ2

N. S. Laursen, T. Vorup-Jensen, H. Pedersen, 2022, The Journal of biological chemistry.

Structure-Guided Engineering of a Complement Component C3-Binding Nanobody Improves Specificity and Adds Cofactor Activity

N. S. Laursen, S. Thiel, A. Hansen, 2022, Frontiers in Immunology.

Structural signatures in EPR3 define a unique class of plant carbohydrate receptors

N. S. Laursen, P. Azadi, C. Ronson, 2020, Nature Communications.

Nanobody‐mediated complement activation to kill HIV‐infected cells

N. S. Laursen, M. Tolstrup, L. Østergaard, 2022, bioRxiv.

Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus

N. S. Laursen, M. Bjerre, J. Fraser, 2010, Proceedings of the National Academy of Sciences.

Complement activation by human IgG antibodies to galactose‐α‐1,3‐galactose

N. S. Laursen, S. Thiel, J. Jensenius, 2020, Immunology.

Substrate recognition by complement convertases revealed in the C5–cobra venom factor complex

N. S. Laursen, I. Braren, L. Sottrup-jensen, 2011, The EMBO journal.

Structure of and influence of a tick complement inhibitor on human complement component 5

N. S. Laursen, J. S. Pedersen, P. Roversi, 2008, Nature Immunology.

An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase

N. S. Laursen, S. Thiel, A. Hansen, 2020, The Journal of Immunology.

Structural basis for activation of the complement system by component C4 cleavage

N. S. Laursen, S. Thiel, T. R. Kjaer, 2012, Proceedings of the National Academy of Sciences.

Nanobodies Provide Insight into the Molecular Mechanisms of the Complement Cascade and Offer New Therapeutic Strategies

N. S. Laursen, A. Zarantonello, H. Pedersen, 2021, Biomolecules.

Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction

Edzard Spillner, N. S. Laursen, T. Jakob, 2018, Nature Communications.

Highly Conserved Protective Epitopes on Influenza B Viruses

N. S. Laursen, L. Poon, I. Wilson, 2012, Science.

Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System

N. S. Laursen, K. Lindorff-Larsen, S. Thiel, 2019, Front. Immunol..

Antibody Recognition of the Pandemic H1N1 Influenza Virus Hemagglutinin Receptor Binding Site

James E. Crowe, Andrew B. Ward, Xueyong Zhu, 2013, Journal of Virology.

Broadly neutralizing antibodies against influenza viruses.

N. S. Laursen, I. Wilson, 2013, Antiviral research.

Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin

Jinquan Luo, Galina Obmolova, Andrew B. Ward, 2018, Science.

Structure, function and control of complement C5 and its proteolytic fragments.

N. S. Laursen, F. Magnani, R. H. Gottfredsen, 2012, Current molecular medicine.

Trapping IgE in a closed conformation by mimicking CD23 binding prevents and disrupts FcεRI interaction

N. S. Laursen, T. Jakob, M. Miehe, 2018, Nature Communications.

Receptor Mediated Delivery of Cas9-Nanobody Induces Cisplatin Synthetic Dose Sensitivity

N. S. Laursen, U. Akavia, B. Nagar, 2018, bioRxiv.

Recruitment of properdin by bi-specific nanobodies activates the alternative pathway of complement.

N. S. Laursen, S. Thiel, A. Hansen, 2020, Molecular immunology.

Introducing site-specific cysteines into nanobodies for mercury labelling allows de novo phasing of their crystal structures

N. S. Laursen, G. Andersen, S. B. Hansen, 2017, Acta crystallographica. Section D, Structural biology.

Receptor Binding Site H1N1 Influenza Virus Hemagglutinin Antibody Recognition of the Pandemic

N. S. Laursen, I. Wilson, J. Crowe, 2013 .

Structure of the integrin receptor αMβ2 headpiece in complex with a function-modulating nanobody

N. S. Laursen, T. Vorup-Jensen, H. Pedersen, 2021, bioRxiv.

Nanobody‐based human antibody formats act as IgE surrogate in hymenoptera venom allergy

N. S. Laursen, T. Jakob, M. Miehe, 2022, Allergy.

Structure of and influence of a tick complement inhibitor on human complement component 5

N. S. Laursen, P. Roversi, L. Jenner, 2008, Nature Immunology.