Dominique Schols

发表

Alkylated benzimidazoles: Design, synthesis, docking, DFT analysis, ADMET property, molecular dynamics and activity against HIV and YFV

Ritika Srivastava, Vishal Kumar Singh, Parth Sarthi Sen Gupta, 2020, Computational Biology and Chemistry.

Advantages and shortcomings of cell-based electrical impedance measurements as a GPCR drug discovery tool.

Liliane Schoofs, Walter Luyten, Bart Landuyt, 2019, Biosensors & bioelectronics.

AMD3100, a Potent and Specific Antagonist of the Stromal Cell-Derived Factor-1 Chemokine Receptor CXCR4, Inhibits Autoimmune Joint Inflammation in IFN-γ Receptor-Deficient Mice1

Dominique Schols, E. De Clercq, A. Billiau, 2001, The Journal of Immunology.

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

Erik De Clercq, Jan Desmyter, Dominique Schols, 1990, Nature.

Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR 5 / CXCR 4 Antagonist

Erik De Clercq, Dominique Schols, T. Schwartz, 2004 .

Safety, Pharmacokinetics, and Antiviral Activity of AMD3100, a Selective CXCR4 Receptor Inhibitor, in HIV-1 Infection

Dominique Schols, M. Lederman, C. Flexner, 2004, Journal of acquired immune deficiency syndromes.

Mutations at the CXCR4 interaction sites for AMD3100 influence anti‐CXCR4 antibody binding and HIV‐1 entry

Dominique Schols, E. De Clercq, T. Schwartz, 2003, FEBS letters.

Molecular Mechanism of Action of Monocyclam Versus Bicyclam Non-peptide Antagonists in the CXCR4 Chemokine Receptor*

Dominique Schols, T. Schwartz, M. Rosenkilde, 2007, Journal of Biological Chemistry.

Primary mutations selected in vitro with raltegravir confer large fold changes in susceptibility to first-generation integrase inhibitors, but minor fold changes to inhibitors with second-generation resistance profiles.

Dominique Schols, Kurt Hertogs, K. Hertogs, 2010, Virology.

Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist

Dominique Schols, E. De Clercq, T. Schwartz, 2004, Journal of Virology.

Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity

Yi Xue, Jeanne A. Stuckey, Charles M. Rice, 2015, Cell.

Diverging binding capacities of natural LD78β isoforms of macrophage inflammatory protein‐1α to the CC chemokine receptors 1, 3 and 5 affect their anti‐HIV‐1 activity and chemotactic potencies for neutrophils and eosinophils

Dominique Schols, Paul Proost, E. De Clercq, 2001, European journal of immunology.

AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity.

Dominique Schols, D. Schols, G. Bridger, 2002, The American journal of pathology.

Pradimicin A, a Carbohydrate-Binding Nonpeptidic Lead Compound for Treatment of Infections with Viruses with Highly Glycosylated Envelopes, Such as Human Immunodeficiency Virus

Jan Balzarini, Toshikazu Oki, Dominique Schols, 2006, Journal of Virology.

Amino-terminal Truncation of Chemokines by CD26/Dipeptidyl-peptidase IV

Dominique Schols, Paul Proost, E. De Clercq, 1998, The Journal of Biological Chemistry.

HIV chemokine receptor inhibitors as novel anti-HIV drugs.

Dominique Schols, D. Schols, Katrien Princen, 2005, Cytokine & growth factor reviews.

Discovery of novel small molecule orally bioavailable C-X-C chemokine receptor 4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication.

Dominique Schols, E. De Clercq, D. Schols, 2010, Journal of medicinal chemistry.

AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor.

Dominique Schols, E. De Clercq, T. Schwartz, 2005, Biochemical pharmacology.