M Danhof

发表

Kinetics of drug action in disease states. V. Acute effect of urea infusion on phenobarbital concentrations in rats at onset of loss of righting reflex.

G Levy, M Danhof, M. Danhof, 1985, The Journal of pharmacology and experimental therapeutics.

Relevance of the Application of Pharmacokinetic-Pharmacodynamic Modelling Concepts in Drug Development

M Danhof, D D Breimer, M. Danhof, 1997, Clinical pharmacokinetics.

Kinetics of drug action in disease states. I. Effect of infusion rate on phenobarbital concentrations in serum, brain and cerebrospinal fluid of normal rats at onset of loss of righting reflex.

G Levy, M Danhof, M. Danhof, 1984, The Journal of pharmacology and experimental therapeutics.

Kinetics of drug action in disease states. IV. Effect of pregnancy on phenobarbital concentrations at onset of loss of righting reflex in rats.

G Levy, M Danhof, 1985, The Journal of pharmacology and experimental therapeutics.

Kinetics of drug action in disease states. II. Effect of experimental renal dysfunction on phenobarbital concentrations in rats at onset of loss of righting reflect.

G Levy, M Hisaoka, M Danhof, 1984, The Journal of pharmacology and experimental therapeutics.

Pharmacokinetic‐pharmacodynamic modeling of midazolam effects on the human central nervous system

M Danhof, M. Danhof, J Dingemanse, 1988, Clinical pharmacology and therapeutics.

Relevance of arteriovenous concentration differences in pharmacokinetic-pharmacodynamic modeling of midazolam.

M Danhof, M. Danhof, J. Mandema, 1998, The Journal of pharmacology and experimental therapeutics.

Analysis of drug-receptor interactions in vivo: a new approach in pharmacokinetic-pharmacodynamic modelling.

M Danhof, M. Danhof, P. H. van der Graaf, 1997, International journal of clinical pharmacology and therapeutics.

Pharmacokinetic-pharmacodynamic characterization of the cardiovascular, hypnotic, EEG and ventilatory responses to dexmedetomidine in the rat.

M Danhof, D R Stanski, M. Danhof, 1997, The Journal of pharmacology and experimental therapeutics.

Assessing the Probability of Drug‐Induced QTc‐Interval Prolongation During Clinical Drug Development

O Della Pasqua, M Danhof, M. Danhof, 2011, Clinical pharmacology and therapeutics.

Mechanism-based pharmacokinetic-pharmacodynamic modeling of antilipolytic effects of adenosine A(1) receptor agonists in rats: prediction of tissue-dependent efficacy in vivo.

M Danhof, M. Danhof, A. IJzerman, 1999, The Journal of pharmacology and experimental therapeutics.

Establishing in vitro to clinical correlations in the evaluation of cardiovascular safety pharmacology.

M Danhof, M. Danhof, O. Della Pasqua, 2013, Drug discovery today. Technologies.

Validation and testing of a new iontophoretic continuous flow through transport cell.

M Danhof, M. Danhof, H. Boddé, 1998, Journal of controlled release : official journal of the Controlled Release Society.

Pharmacokinetic-pharmacodynamic modeling of the anticonvulsant and electroencephalogram effects of phenytoin in rats.

M Danhof, M. Danhof, R. Voskuyl, 1998, The Journal of pharmacology and experimental therapeutics.

Pharmacokinetic-pharmacodynamic modeling of the electroencephalographic effects of benzodiazepines. Correlation with receptor binding and anticonvulsant activity.

M Danhof, M. Danhof, L. Sansom, 1991, The Journal of pharmacology and experimental therapeutics.

Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of the Electroencephalogram Effects of GABAA Receptor Modulators: In Vitro-in Vivo Correlations

M Danhof, L. Peletier, M. Danhof, 2003, Journal of Pharmacology and Experimental Therapeutics.

Mechanism-based pharmacokinetic-pharmacodynamic modeling of the effects of N6-cyclopentyladenosine analogs on heart rate in rat: estimation of in vivo operational affinity and efficacy at adenosine A1 receptors.

M Danhof, M. Danhof, A. IJzerman, 1997, The Journal of pharmacology and experimental therapeutics.

Differences in intrinsic efficacy of benzodiazepines are reflected in their concentration‐EEG effect relationship

M Danhof, M. Danhof, J. Mandema, 1992, British journal of pharmacology.

Characterization of the pharmacodynamic interaction between parent drug and active metabolite in vivo: midazolam and alpha-OH-midazolam.

M Danhof, M. Danhof, J. Mandema, 1999, The Journal of pharmacology and experimental therapeutics.

A set-point model with oscillatory behavior predicts the time course of 8-OH-DPAT-induced hypothermia.

P H van der Graaf, M Danhof, L. Peletier, 2001, American journal of physiology. Regulatory, integrative and comparative physiology.

A system approach to pharmacodynamics. III: An algorithm and computer program, COLAPS, for pharmacodynamic modeling.

M Danhof, P Veng-Pedersen, J W Mandema, 1991, Journal of pharmaceutical sciences.

Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs.

M Danhof, D D Breimer, M. Danhof, 1988, The Journal of pharmacology and experimental therapeutics.

Multivariate quantitative structure-pharmacokinetic relationships (QSPKR) analysis of adenosine A1 receptor agonists in rat.

M Danhof, M. Danhof, P. H. van der Graaf, 1999, Journal of pharmaceutical sciences.