Dennis E Discher

发表

Rationally engineered advances in cancer research

Adam J Engler, Dennis E Discher, D. Discher, 2018, APL bioengineering.

Stem cell mechanobiology: diverse lessons from bone marrow.

Jae-Won Shin, Dennis E Discher, Joe Swift, 2015, Trends in cell biology.

Striated acto-myosin fibers can reorganize and register in response to elastic interactions with the matrix.

Dennis E Discher, Benjamin M Friedrich, D. Discher, 2011, Biophysical journal.

Self-assembly and properties of diblock copolymers by coarse-grain molecular dynamics

Michael L Klein, Dennis E Discher, M. Klein, 2004, Nature materials.

Endothelial targeting of antibody-decorated polymeric filomicelles.

Silvia Muro, Dennis E Discher, Eric Simone, 2011, ACS nano.

Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties.

Dennis E Discher, D. Discher, K. Spinler, 2015, Current opinion in immunology.

Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels.

Dennis E Discher, D. Discher, R. Tsai, 2010, Blood cells, molecules & diseases.

How deeply cells feel: methods for thin gels

Dennis E Discher, André E. X. Brown, D. Discher, 2010, Journal of physics. Condensed matter : an Institute of Physics journal.

Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells ‘feel’ outside and in?

Dennis E Discher, D. Discher, A. Buxboim, 2010, Journal of Cell Science.

Mitotic progression following DNA damage enables pattern recognition within micronuclei

Dennis E Discher, R. Greenberg, A. Minn, 2017, Nature.

The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation.

Dennis E Discher, Robert J Levy, Stanley J Stachelek, 2011, Biomaterials.

Indentation and adhesive probing of a cell membrane with AFM: theoretical model and experiments.

Shamik Sen, Dennis E Discher, S. Sen, 2005, Biophysical journal.

Nanoparticle Shape Improves Delivery: Rational Coarse Grain Molecular Dynamics (rcg-md) of Taxol in Worm-like Peg-pcl Micelles 2

Michael L Klein, Dennis E Discher, Sharon M. Loverde, 2022 .

Flexible filaments for in vivo imaging and delivery: persistent circulation of filomicelles opens the dosage window for sustained tumor shrinkage.

Dennis E Discher, D. Discher, T. Minko, 2009, Molecular pharmaceutics.

Daniel Safer, Dennis E Discher, André E. X. Brown, 2009, Biophysical journal.

Nuclear Lamins in Cancer

Dennis E Discher, Joe Swift, J. Irianto, 2016, Cellular and molecular bioengineering.

Adhesively-tensed cell membranes: lysis kinetics and atomic force microscopy probing.

Dennis E Discher, D. Discher, A. Hategan, 2003, Biophysical journal.

Dissipative particle dynamics simulations of polymersomes.

Reinhard Lipowsky, Michael L Klein, Dennis E Discher, 2005, The journal of physical chemistry. B.

Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug.

Frank Bates, Dennis E Discher, F. Bates, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Divalent cation-dependent formation of electrostatic PIP2 clusters in lipid monolayers.

Andrea J Liu, Andrea J. Liu, Dennis E Discher, 2011, Biophysical journal.

Material control of stem cell differentiation: challenges in nano-characterization.

Dennis E Discher, D. Discher, P. D. Dingal, 2014, Current opinion in biotechnology.

Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: pH-triggered release through copolymer degradation.

Frank Bates, Michael L Klein, Dennis E Discher, 2006, Molecular pharmaceutics.

Filomicelles from aromatic diblock copolymers increase paclitaxel-induced tumor cell death and aneuploidy compared with aliphatic copolymers.

Afsaneh Lavasanifar, Dennis E Discher, D. Discher, 2016, Nanomedicine.

Influence of Lateral Association on Forced Unfolding of Antiparallel Spectrin Heterodimers*

Dennis E Discher, David W Speicher, D. Speicher, 2004, Journal of Biological Chemistry.

Cooperativity in forced unfolding of tandem spectrin repeats.

Dennis E Discher, David W Speicher, D. Speicher, 2003, Biophysical journal.

Matrix Strains Induced by Cells: Computing How Far Cells Can Feel

Shamik Sen, Adam J Engler, Dennis E Discher, 2009, Cellular and molecular bioengineering.

Polymeric worm micelles as nano-carriers for drug delivery

Dennis E Discher, D. Discher, D. Christian, 2005, Nanotechnology.

Developmental biology: Holding it together in the eye

Paul A. Janmey, Dennis E Discher, P. Janmey, 2004, Nature.

Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells.

Florian Rehfeldt, Dennis E Discher, André E. X. Brown, 2012, Integrative biology : quantitative biosciences from nano to macro.

Mechanotransduction in cancer.

Dennis E Discher, P. Janmey, D. Discher, 2016, Current opinion in chemical engineering.

Protein unfolding accounts for the unusual mechanical behavior of fibrin networks.

Dennis E Discher, André E. X. Brown, J. Weisel, 2011, Acta biomaterialia.

Mechanosensing of matrix by stem cells: From matrix heterogeneity, contractility, and the nucleus in pore-migration to cardiogenesis and muscle stem cells in vivo.

Lucas R. Smith, Dennis E Discher, Sangkyun Cho, 2017, Seminars in cell & developmental biology.

The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber

Dennis E Discher, Kris Noel Dahl, D. Discher, 2004, Journal of Cell Science.

Topographical pattern dynamics in passive adhesion of cell membranes.

Dennis E Discher, Erich Sackmann, Kheya Sengupta, 2004, Biophysical journal.

Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

Adam J Engler, Dennis E Discher, David W Speicher, 2008, Journal of Cell Science.

Chemistry on a Single Protein, Vascular Cell Adhesion Molecule-1, during Forced Unfolding*

Hui Lu, Dennis E Discher, David W Speicher, 2004, Journal of Biological Chemistry.

Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles.

Dennis E Discher, D. Discher, F. Ahmed, 2004, Journal of controlled release : official journal of the Controlled Release Society.

Stem cells feel the difference

Dennis E Discher, D. Discher, A. Buxboim, 2010, Nature Methods.

Emerging Applications of Polymersomes in Delivery: from Molecular Dynamics to Shrinkage of Tumors.

Michael L Klein, Dennis E Discher, M. Klein, 2007, Progress in polymer science.

Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance.

Timothy J Gardner, Adam J Engler, Dennis E Discher, 2007, American journal of physiology. Heart and circulatory physiology.

Species- and cell type-specific interactions between CD47 and human SIRPalpha.

Shamik Sen, Dennis E Discher, S. Sen, 2006, Blood.

Microtissue elasticity: measurements by atomic force microscopy and its influence on cell differentiation.

Shamik Sen, Florian Rehfeldt, Adam J Engler, 2007, Methods in cell biology.

Minimal " Self " Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles References and Notes

Dennis E Discher, F. Tanser, D. Discher, 2022 .

Polymersome carriers: from self-assembly to siRNA and protein therapeutics.

Dennis E Discher, D. Discher, D. Christian, 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Unfolding a linker between helical repeats.

Michael L Klein, Dennis E Discher, Steven O Nielsen, 2005, Journal of molecular biology.