Shoshana D. Brown

发表

Discovery of new enzymes and metabolic pathways using structure and genome context

Ritesh Kumar, Patricia C. Babbitt, Steven C. Almo, 2016 .

The Structure–Function Linkage Database

Michael A. Hicks, John H. Morris, Conrad C. Huang, 2006, Nucleic Acids Res..

Annotation Error in Public Databases: Misannotation of Molecular Function in Enzyme Superfamilies

Patricia C. Babbitt, Shoshana D. Brown, Alexandra M. Schnoes, 2009, PLoS Comput. Biol..

Representing Structure-Function Relationships in Mechanistically Diverse Enzyme Superfamilies

Conrad C. Huang, Thomas E. Ferrin, Patricia C. Babbitt, 2004, Pacific Symposium on Biocomputing.

InterPro in 2019: improving coverage, classification and access to protein sequence annotations

Silvio C. E. Tosatto, Neil D. Rawlings, Robert D. Finn, 2018, Nucleic Acids Res..

Biocuration in the structure–function linkage database: the anatomy of a superfamily

Michael A. Hicks, John H. Morris, Conrad C. Huang, 2017, Database J. Biol. Databases Curation.

Leveraging enzyme structure-function relationships for functional inference and experimental design: the structure-function linkage database.

Conrad C. Huang, Shoshana D. Brown, John H. Morris, 2006, Biochemistry.

A gold standard set of mechanistically diverse enzyme superfamilies

Shoshana D. Brown, P. Babbitt, J. Gerlt, 2006, Genome Biology.

Prediction and assignment of function for a divergent N-succinyl amino acid racemase.

Heidi J. Imker, Shoshana D. Brown, P. Babbitt, 2007, Nature chemical biology.

At the periphery of the amidohydrolase superfamily: Bh0493 from Bacillus halodurans catalyzes the isomerization of D-galacturonate to D-tagaturonate.

Shoshana D. Brown, P. Babbitt, A. Fedorov, 2008, Biochemistry.

Inference of Functional Properties from Large-scale Analysis of Enzyme Superfamilies*

Shoshana D. Brown, P. Babbitt, 2011, The Journal of Biological Chemistry.

Homology models guide discovery of diverse enzyme specificities among dipeptide epimerases in the enolase superfamily

Shoshana D. Brown, P. Babbitt, J. Gerlt, 2012, Proceedings of the National Academy of Sciences.

Consequences of domain insertion on sequence-structure divergence in a superfold

Shoshana D. Brown, Karen N. Allen, A. Sali, 2013, Proceedings of the National Academy of Sciences.

A semiautomated approach to gene discovery through expressed sequence tag data mining: Discovery of new human transporter genes

Shoshana D. Brown, Jean L. Chang, P. Babbitt, 2003, AAPS PharmSci.

Covalent Docking Predicts Substrates for Haloalkanoate Dehalogenase Superfamily Phosphatases

Nir London, Patricia C. Babbitt, Brian K. Shoichet, 2014, Biochemistry.

New Insights about Enzyme Evolution from Large Scale Studies of Sequence and Structure Relationships*

Patricia C. Babbitt, Shoshana D. Brown, P. Babbitt, 2014, The Journal of Biological Chemistry.

Target selection and annotation for the structural genomics of the amidohydrolase and enolase superfamilies

Stephen K. Burley, Narayanan Eswar, Ursula Pieper, 2009, Journal of Structural and Functional Genomics.

Representing Enzyme Function in Mechanistically Diverse Enzyme Superfamilies

Shoshana D. Brown, P. Babbitt, S. Pegg, 2007 .

An approach to functionally relevant clustering of the protein universe: Active site profile‐based clustering of protein structures and sequences

Janelle B. Leuthaeuser, Angela F. Harper, Shoshana D. Brown, 2017, Protein science : a publication of the Protein Society.

Evolution of enzymatic activities in the enolase superfamily: stereochemically distinct mechanisms in two families of cis,cis-muconate lactonizing enzymes.

Patricia C Babbitt, Stephen K Burley, Ayano Sakai, 2009, Biochemistry.

Biocuration in the structure–function linkage database: the anatomy of a superfamily

Conrad C. Huang, Thomas E. Ferrin, Elaine C. Meng, 2017, Database : the journal of biological databases and curation.

Structural diversity within the mononuclear and binuclear active sites of N-acetyl-D-glucosamine-6-phosphate deacetylase.

Shoshana D. Brown, P. Babbitt, A. Fedorov, 2007, Biochemistry.

Implementation of the FAIR Data Principles for Exploratory Biomarker Data from Clinical Trials

Shoshana D. Brown, Diya Das, C. Farhy, 2021, Data Intelligence.

Using the Structure‐Function Linkage Database to Characterize Functional Domains in Enzymes

Shoshana D. Brown, P. Babbitt, 2006, Current protocols in bioinformatics.

Using the Structure‐Function Linkage Database to Characterize Functional Domains in Enzymes

Shoshana D. Brown, P. Babbitt, 2006, Current protocols in bioinformatics.

OP-NARE131129 521..530

Conrad C. Huang, Gemma L. Holliday, Shoshana D. Brown, 2013 .

Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha[OPEN]

Shoshana D. Brown, P. Babbitt, S. Mafu, 2016, Plant Cell.

Kinetics of the deprotonation of methylnitroacetate by amines: unusually high intrinsic rate constants for a nitroalkane.

Shoshana D. Brown, C. F. Bernasconi, M. Pérez-Lorenzo, 2007, The Journal of organic chemistry.

Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

Eyal Akiva, Matthew P Jacobson, Suwen Zhao, 2014, eLife.

Determinants of the CmoB carboxymethyl transferase utilized for selective tRNA wobble modification

Shoshana D. Brown, P. Babbitt, S. Almo, 2015, Nucleic acids research.

Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain.

Ursula Pieper, Eyal Akiva, Gemma L. Holliday, 2018, Methods in enzymology.

Structure-guided discovery of carboxy-SAM as a novel metabolite modulating tRNA function

Shoshana D. Brown, P. Babbitt, S. Almo, 2013, Nature.

Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function

Patricia C. Babbitt, Steven C. Almo, Hui Xiao, 2013, Nature.

Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.

Shoshana D. Brown, P. Babbitt, A. Fedorov, 2009, Biochemistry.

Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.

Shoshana D. Brown, P. Babbitt, B. Medellin, 2020, Biochemistry.

Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.

Shoshana D. Brown, P. Babbitt, E. Akiva, 2019, Biochemistry.

Discovery of new enzymes and metabolic pathways using structure and genome context

Shoshana D. Brown, P. Babbitt, J. Gerlt, 2013, Nature.

At the Periphery of the Amidohydrolase Superfamily : Bh 0493 from Bacillus halodurans Catalyzes the Isomerization ofD-Galacturonate

Shoshana D. Brown, P. Babbitt, A. Fedorov, 2022 .

Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a “Plug & Play” Domain

Gemma L. Holliday, Shoshana D. Brown, A. Sali, 2019 .

Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.

Shoshana D. Brown, P. Babbitt, A. Fedorov, 2009, Biochemistry.