Paul A Johnston

发表

High-Content Imaging and Informatics: A Joint Special Issue with Society for Biomolecular Imaging and Informatics and SLAS

Myles Fennell, Paul A Johnston, 2020, SLAS discovery : advancing life sciences R & D.

Identifying Actives from HTS Data Sets

Paul A Johnston, Tong Ying Shun, John S Lazo, 2011, Journal of biomolecular screening.

Requirements, features, and performance of high content screening platforms.

Paul A Johnston, Albert H Gough, A. Gough, 2007, Methods in molecular biology.

Standardization of high content imaging and informatics.

Paul A Johnston, O Joseph Trask, 2015, Assay and drug development technologies.

Assay development and case history of a 32K-biased library high-content MK2-EGFP translocation screen to identify p38 mitogen-activated protein kinase inhibitors on the ArrayScan 3.1 imaging platform.

Paul A Johnston, Oscar J Trask, O. J. Trask, 2006, Methods in enzymology.

Design and activity of AP endonuclease-1 inhibitors

Zhiwei Feng, Xiang-Qun Xie, Paul A Johnston, 2015, Journal of chemical biology.

Redox cycling compounds generate H2O2 in HTS buffers containing strong reducing reagents--real hits or promiscuous artifacts?

Paul A Johnston, P. Johnston, 2011, Current opinion in chemical biology.

Development and validation of a high-content screening assay to identify inhibitors of cytoplasmic dynein-mediated transport of glucocorticoid receptor to the nucleus.

Paul A Johnston, Billy W Day, Tong Ying Shun, 2012, Assay and drug development technologies.

High-throughput automated confocal microscopy imaging screen of a kinase-focused library to identify p38 mitogen-activated protein kinase inhibitors using the GE InCell 3000 analyzer.

Paul A Johnston, O Joseph Trask, O. J. Trask, 2009, Methods in molecular biology.

Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments.

Peter Wipf, Paul A Johnston, Tong Ying Shun, 2010, Assay and drug development technologies.

Synthesis and Biological Activity of a Focused Library of Mitogen‐activated Protein Kinase Phosphatase Inhibitors

Peter Wipf, Paul A Johnston, Donna M Huryn, 2007, Chemical biology & drug design.

Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents.

Peter Wipf, Paul A Johnston, Tong Ying Shun, 2008, Assay and drug development technologies.

Cellular platforms for HTS: three case studies.

Paul A Johnston, P. Johnston, P. Johnston, 2002, Drug discovery today.