Timothy P. Sheahan

Hypergraph models of biological networks to identify genes critical to pathogenic viral response

Qing Tan, Cliff Joslyn, Brenda Praggastis, 2020, BMC Bioinform..

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus

Alexandra Schäfer, Ralph S. Baric, Amy C. Sims, 2020, bioRxiv.

Remdesivir potently inhibits SARS-CoV-2 in human lung cells and chimeric SARS-CoV expressing the SARS-CoV-2 RNA polymerase in mice

Xiaotao Lu, Alexandra Schäfer, Ralph S. Baric, 2020, bioRxiv.

An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice

Xiaotao Lu, Alexandra Schäfer, Ralph S. Baric, 2020, Science Translational Medicine.

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

Xiaotao Lu, Ralph S. Baric, Amy C. Sims, 2018, mBio.