Michael C O'Donovan

发表

Predictive modeling of schizophrenia from genomic data: Comparison of polygenic risk score with kernel support vector machines approach

Peter Holmans, Andreas Artemiou, Andrew Pocklington, 2018, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

DNA pooling as a tool for large‐scale association studies in complex traits

Michael C O'Donovan, Michael J Owen, Nadine Norton, 2004, Annals of medicine.

Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

Alexander Gusev, Bogdan Pasaniuc, Nicholas Mancuso, 2016, Nature Genetics.

Psychiatric Genomics: An Update and an Agenda

Gerome Breen, Sven Cichon, Patrick F Sullivan, 2017, bioRxiv.

Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof-of-concept and roadmap for future studies

Anbupalam Thalamuthu, Thomas E. Nichols, Manuel Mattheisen, 2016, Nature Neuroscience.

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

Jakob Grove, Esben Agerbo, Robert Plomin, 2018, Nature Genetics.

Functional analysis of polymorphisms in the promoter regions of genes on 22q11

Michael C O'Donovan, M. O’Donovan, P. Buckland, 2004, Human mutation.

Haplotypes at the dystrobrevin binding protein 1 (DTNBP1) gene locus mediate risk for schizophrenia through reduced DTNBP1 expression.

Michael C O'Donovan, Michael J Owen, Nigel M Williams, 2005, Human molecular genetics.

Methylomic trajectories across human fetal brain development

Michael C O'Donovan, Eilis Hannon, Helen Spiers, 2015, Genome research.

Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

Hae Kyung Im, Solveig K Sieberts, Kiran Girdhar, 2019, Nature Genetics.

A high proportion of chromosome 21 promoter polymorphisms influence transcriptional activity.

Michael C O'Donovan, M. O’Donovan, P. Buckland, 2004, Gene expression.

Effects of pathogenic CNVs on physical traits in participants of the UK Biobank

Michael C O'Donovan, Michael J Owen, Valentina Escott-Price, 2018, BMC Genomics.

Genome-wide association study of multiplex schizophrenia pedigrees.

Jianxin Shi, Stephan Ripke, Pablo V Gejman, 2012, The American journal of psychiatry.

Strong evidence for association between the dystrobrevin binding protein 1 gene (DTNBP1) and schizophrenia in 488 parent-offspring trios from Bulgaria

Ivan Nikolov, Michael C O'Donovan, Michael J Owen, 2004, Biological Psychiatry.

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

Jianxin Shi, Susmita Datta, Aribert Rothenberger, 2013, Nature Genetics.

Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

Jakob Grove, Esben Agerbo, Andres Metspalu, 2017, bioRxiv.

A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain.

Michael C O'Donovan, Michael J Owen, Nadine Norton, 2003, American journal of human genetics.

Experimental analysis of the annotation of promoters in the public database.

Michael C O'Donovan, M. O’Donovan, P. Buckland, 2002, Human molecular genetics.

Phenotypic and genetic complexity of psychosis

Nick Craddock, Michael C O'Donovan, Michael J Owen, 2007, British Journal of Psychiatry.

Promoter polymorphisms in glutathione-S-transferase genes affect transcription.

Michael C O'Donovan, M. O’Donovan, P. Buckland, 2004, Pharmacogenetics.

Strong bias in the location of functional promoter polymorphisms

Michael C O'Donovan, M. O’Donovan, P. Buckland, 2005, Human mutation.

Schizophrenia risk alleles and neurodevelopmental outcomes in childhood: a population-based cohort study.

Barbara Maughan, Michael C O'Donovan, Stephan Collishaw, 2017, The lancet. Psychiatry.

Support for RGS4 as a susceptibility gene for schizophrenia

Michael C O'Donovan, Michael J Owen, Nadine Norton, 2004, Biological Psychiatry.

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Minna Männikkö, David Curtis, Peter Holmans, 2016, Nature Neuroscience.

Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk.

Peter Holmans, Alexandra Durr, Manu Sharma, 2013, JAMA neurology.

A data‐driven investigation of relationships between bipolar psychotic symptoms and schizophrenia genome‐wide significant genetic loci

Ganna Leonenko, Nick Craddock, Michael C O'Donovan, 2018, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia.

Leena Peltonen, Andrew McQuillin, Jouko Lönnqvist, 2003, American journal of human genetics.