Thomas M Frimurer

发表

Drug design of GPCR ligands using physicogenetics and chemogenomics--principles and case studies.

Thomas Högberg, Thomas M Frimurer, 2011, Current topics in medicinal chemistry.

Ligand binding and micro-switches in 7TM receptor structures.

Thomas M Frimurer, Birgitte Holst, T. Schwartz, 2009, Trends in pharmacological sciences.

Melanin concentrating hormone receptor 1 (MCHR1) antagonists-Still a viable approach for obesity treatment?

Thomas M Frimurer, T. Frimurer, T. Högberg, 2012, Bioorganic & medicinal chemistry letters.

In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist

Thomas M Frimurer, Birgitte Holst, T. Frimurer, 2016, Molecular informatics.

Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits.

Evi Kostenis, Thomas M Frimurer, Trond Ulven, 2006, Journal of medicinal chemistry.

PheVI:09 (Phe6.44) as a Sliding Microswitch in Seven-transmembrane (7TM) G Protein-coupled Receptor Activation*

Thomas M Frimurer, Birgitte Holst, T. Schwartz, 2012, The Journal of Biological Chemistry.

6-Acylamino-2-aminoquinolines as potent melanin-concentrating hormone 1 receptor antagonists. Identification, structure-activity relationship, and investigation of binding mode.

Thomas M Frimurer, Trond Ulven, T. Frimurer, 2005, Journal of medicinal chemistry.

Ligand-induced conformational changes: improved predictions of ligand binding conformations and affinities.

Thomas M Frimurer, O. Olsen, T. Frimurer, 2003, Biophysical journal.

A Conserved Aromatic Lock for the Tryptophan Rotameric Switch in TM-VI of Seven-transmembrane Receptors*

Thomas M Frimurer, Birgitte Holst, T. Schwartz, 2009, The Journal of Biological Chemistry.

Overlapping Binding Site for the Endogenous Agonist, Small-Molecule Agonists, and Ago-allosteric Modulators on the Ghrelin Receptor

Thomas M Frimurer, Birgitte Holst, T. Schwartz, 2009, Molecular Pharmacology.

A physicogenetic method to assign ligand-binding relationships between 7TM receptors.

Evi Kostenis, Thomas M Frimurer, Trond Ulven, 2005, Bioorganic & medicinal chemistry letters.