Volker Hovestadt

发表

Resolving medulloblastoma cellular architecture by single-cell genomics

Volker Hovestadt, Kyle S. Smith, Laure Bihannic, 2019, Nature.

Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data

Martin Sill, Volker Hovestadt, Andreas von Deimling, 2020, Nature Protocols.

DNA methylation-based classification of central nervous system tumours

Till Acker, Pieter Wesseling, Martin Sill, 2018, Nature.

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Roland Eils, Sebastian M. Waszak, Jan O. Korbel, 2016, Nature.

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

Roland Eils, Paul Flicek, Helene Kretzmer, 2015, Nature Genetics.

Recurrent MET fusion genes represent a drug target in pediatric glioblastoma

Roland Eils, Thomas Zichner, Hans Lehrach, 2016, Nature Medicine.

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

Volker Hovestadt, Stefan M. Pfister, Paul A. Northcott, 2014, Acta Neuropathologica.

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1

Rainer König, Volker Hovestadt, Ralf Kemkemer, 2013, Nature Medicine.

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis.

Martin Sill, Michael Platten, Volker Hovestadt, 2017, The Lancet. Oncology.

The whole-genome landscape of medulloblastoma subtypes

Roland Eils, Steven J. M. Jones, Sebastian M. Waszak, 2017, Nature.

Dissecting the genomic complexity underlying medulloblastoma

Matthew J. Betts, Robert B. Russell, Roland Eils, 2012, Nature.

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

Volker Hovestadt, Stefan M. Pfister, Felix Sahm, 2015, Acta Neuropathologica.

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

Volker Hovestadt, Stefan M. Pfister, Paul A. Northcott, 2013, Acta Neuropathologica.

Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial.

Martin Sill, Michael Platten, Volker Hovestadt, 2014, Neuro-oncology.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Volker Hovestadt, Stefan M. Pfister, Brent A. Orr, 2016, Cell.

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO

Pieter Wesseling, Jaap C. Reijneveld, Volker Hovestadt, 2015, Acta Neuropathologica.

Melanotic Tumors of the Nervous System are Characterized by Distinct Mutational, Chromosomal and Epigenomic Profiles

Volker Hovestadt, Felix Sahm, David T. W. Jones, 2015, Brain pathology.

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

Roland Eils, Rainer König, Gary D Bader, 2014, Cancer cell.

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

Roland Eils, Thomas Zichner, Hans Lehrach, 2013, Nature Genetics.

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Tracy T Batchelor, Volker Hovestadt, Mariella G. Filbin, 2018, Science.

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing

Roland Eils, Thomas Zichner, Volker Hovestadt, 2012, BMC Proceedings.

Tagmentation-based whole-genome bisulfite sequencing

Roland Eils, Volker Hovestadt, Jay Shendure, 2013, Nature Protocols.

Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma

Volker Hovestadt, Hendrik Witt, Andrey Korshunov, 2013, Acta Neuropathologica.

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

Volker Hovestadt, Stefan M. Pfister, Andrey Korshunov, 2015, Acta Neuropathologica.

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity

Pieter Wesseling, Martin Sill, Volker Hovestadt, 2016, Brain pathology.

Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas

Roland Eils, Thomas Wolf, Volker Hovestadt, 2013, Genome Biology.

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups.

Martin Sill, Volker Hovestadt, Andreas von Deimling, 2016, Neuro-oncology.

Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity

Volker Hovestadt, Stefan M. Pfister, Arie Perry, 2013, Acta Neuropathologica.

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience

Martin Sill, Volker Hovestadt, Stefan M. Pfister, 2018, Acta Neuropathologica.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Roland Eils, Pieter Wesseling, Martin Sill, 2016, Cell.

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes.

Roland Eils, Volker Hovestadt, Jan Koster, 2016, Cancer cell.

Molecular and Cellular Pathobiology MicroRNA Sequence and Expression Analysis in Breast Tumors by Deep Sequencing

Volker Hovestadt, Thomas Tuschl, Markus Hafner, 2011 .

Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes

Martin Sill, Volker Hovestadt, Stefan M. Pfister, 2019, Acta Neuropathologica.

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

Volker Hovestadt, Stefan M. Pfister, Paul A. Northcott, 2015, Nature Communications.

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

Volker Hovestadt, Stefan M. Pfister, Arie Perry, 2016, Acta Neuropathologica.

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

Martin Sill, Alexander Radbruch, Volker Hovestadt, 2014, Acta Neuropathologica.

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

Jennifer A. Doudna, Volker Hovestadt, Stefan M. Pfister, 2016, Oncotarget.