David A. Hafler

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Chapter 3 - Uncovering the Genetic Architecture of Multiple Sclerosis

Philip L. De Jager, David A. Hafler, D. Hafler, 2010 .

From Big Data to Precision Medicine

Alan R. Moody, Tim Hulsen, David A. Hafler, 2019, Front. Med..

CRRAO Advanced Institute of Mathematics, Statistics and Computer Science (AIMSCS)

Jill P. Mesirov, Geoffrey J. McLachlan, Sharon X. Lee, 2013 .

Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

Clare Baecher-Allan, David A. Hafler, Howard L. Weiner, 2004, The Journal of experimental medicine.

MHC Class II Expression Identifies Functionally Distinct Human Regulatory T Cells1

Clare Baecher-Allan, David A. Hafler, C. Baecher-Allan, 2006, The Journal of Immunology.

A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis

Margaret A. Pericak-Vance, Stephen L. Hauser, Jorge R. Oksenberg, 2010, Genes and Immunity.

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

Steven H. Kleinstein, George Church, David Pitt, 2014, Science Translational Medicine.

Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls.

Sandra D'Alfonso, Hanne F. Harbo, Bernhard Hemmer, 2013, American journal of human genetics.

Allelic Variation of MHC Structure Alters Peptide Ligands to Induce Atypical Partial Agonistic CD8+ T Cell Function

David A. Hafler, Katarzyna Bourcier, D. Hafler, 2003, The Journal of experimental medicine.

TGF-β Induces IL-9 Production from Human Th17 Cells

Samia J. Khoury, Clare Baecher-Allan, David A. Hafler, 2010, The Journal of Immunology.

Polyfunctional responses by human T cells result from sequential release of cytokines

Douglas A. Lauffenburger, Neda Bagheri, J. Christopher Love, 2011, Proceedings of the National Academy of Sciences.

Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses

Raphael Gottardo, Jacob Frelinger, Yuri Kotliarov, 2017, Science Immunology.

Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci

Margaret A. Pericak-Vance, Stephen L. Hauser, Jorge R. Oksenberg, 2009, Human molecular genetics.

Genome-Wide Assessment for Genetic Variants Associated with Ventricular Dysfunction after Primary Coronary Artery Bypass Graft Surgery

Dan M. Roden, Christine E. Seidman, Kuang-Yu Liu, 2011, PloS one.

A knowledge-driven interaction analysis reveals potential neurodegenerative mechanism of multiple sclerosis susceptibility

Ludwig Kappos, Stephen L. Hauser, Marylyn D. Ritchie, 2010, Genes and Immunity.

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

Manolis Kellis, Aviv Regev, Nir Hacohen, 2014, Science.

Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data

Steven H. Kleinstein, Gur Yaari, Mohamed Uduman, 2013, Front. Immunol..

F.21Characterization of the Myelin Specific Autoantibodies in Acute Disseminated Encephalomyelitis

Laura Lovato, David A. Hafler, D. Hafler, 2010 .

Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases

Stephen L. Hauser, Jorge R. Oksenberg, Gilean McVean, 2009, Proceedings of the National Academy of Sciences.

The role of the CD58 locus in multiple sclerosis

Margaret A. Pericak-Vance, Stephen L. Hauser, Jorge R. Oksenberg, 2009, Proceedings of the National Academy of Sciences.

Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

Daphne Koller, Aviv Regev, Nir Hacohen, 2014, Science.

Allelic variant in CTLA4 alters T cell phosphorylation patterns

Linda S. Wicker, David A. Hafler, David E. Anderson, 2007, Proceedings of the National Academy of Sciences.

Refining genetic associations in multiple sclerosis

Hanne F. Harbo, Margaret A. Pericak-Vance, Stephen L. Hauser, 2008, The Lancet Neurology.

Suppressor T Cells in Human Diseases

Clare Baecher-Allan, David A. Hafler, C. Baecher-Allan, 2004, The Journal of experimental medicine.

Inhibition of Human CD4+CD25+high Regulatory T Cell Function1

Clare Baecher-Allan, David A. Hafler, C. Baecher-Allan, 2002, The Journal of Immunology.

Pervasive Sharing of Genetic Effects in Autoimmune Disease

Kasper Lage, Gonçalo R. Abecasis, John A. Todd, 2011, PLoS genetics.