William C. Hahn

发表

Abstract SY35-01: Systematic approaches to identify cancer dependencies

William C. Hahn, 2018 .

Simultaneous and exact interval estimates for the contrast of two groups based on an extremely high dimensional variable: application to mass spec data

Cheng Li, Dohyun Kim, William C. Hahn, 2007, Bioinform..

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

Todd R. Golub, Aviad Tsherniak, Joshua M. Dempster, 2018, bioRxiv.

Abstract 4867: Comparative analysis of RNA sequencing methods for characterization of cancer transcriptomics

Samuel S. Hunter, William C. Hahn, Matthew Meyerson, 2015 .

Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

Leopold Parts, Todd R. Golub, John G. Doench, 2019, Nature Communications.

Abstract 4286: Improved FFPE DNA extraction for next generation sequencing using adaptive focused acoustics technology

Ling Lin, William C. Hahn, Matthew Meyerson, 2014 .

Abstract B44: Emerging targets from Cancer Dependency Map v0.1

Todd R. Golub, Aviad Tsherniak, David E. Root, 2017 .

Abstract PR02: Towards a Cancer Dependency Map

Todd R. Golub, Aviad Tsherniak, David E. Root, 2017 .

Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

Keith L. Ligon, Sandro Santagata, Mark A. Rubin, 2009, PloS one.

Analysis of the 10q11 Cancer Risk Locus Implicates MSMB and NCOA4 in Human Prostate Tumorigenesis

Matthew L. Freedman, Stephen J. Chanock, Meir J. Stampfer, 2010, PLoS genetics.

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

Jill P. Mesirov, Dong Gao, Stuart L. Schreiber, 2017, Nature.

Cancer Vulnerabilities Unveiled by Genomic Loss

Jill P. Mesirov, Joseph Rosenbluh, Aviad Tsherniak, 2012, Cell.

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM

Yonghong Xiao, Joseph Rosenbluh, Ian F. Dunn, 2010, Proceedings of the National Academy of Sciences.

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

Pablo Tamayo, Ian F. Dunn, Shuji Ogino, 2008, Nature.

Enumeration of the Simian Virus 40 Early Region Elements Necessary for Human Cell Transformation

Robert A. Weinberg, David M. Sabatini, William C. Hahn, 2002, Molecular and Cellular Biology.

PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

Todd R. Golub, Rameen Beroukhim, Yashaswi Shrestha, 2011, Oncogene.

An activated ErbB3/NRG1 autocrine loop supports in vivo proliferation in ovarian cancer cells.

Birgit Schoeberl, Andrew L. Kung, David M. Livingston, 2010, Cancer cell.

Integrative Genomic Approaches Identify IKBKE as a Breast Cancer Oncogene

Eric S. Lander, Marc Vidal, Ian F. Dunn, 2007, Cell.

Identification of the androgen-induced transcriptional program of human prostate cancer revealed by causal analysis

Phillip G. Febbo, William C. Hahn, K. O. Elliston, 2005 .

Whole exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

Aviv Regev, Kristian Cibulskis, Todd R. Golub, 2014, Nature Biotechnology.

KRAS and YAP1 Converge to Regulate EMT and Tumor Survival

Joseph Rosenbluh, Arjun Bhutkar, William C. Hahn, 2014, Cell.

COT/MAP3K8 drives resistance to RAF inhibition through MAP kinase pathway reactivation

Marc Vidal, Reinhard Dummer, William C. Hahn, 2010, Nature.

A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies

Donna Neuberg, Benjamin L. Ebert, Scott A. Armstrong, 2019, Science.

Towards systematic functional characterization of cancer genomes

William C. Hahn, Jesse S. Boehm, W. Hahn, 2011, Nature Reviews Genetics.

PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas.

Yonghong Xiao, Lynda Chin, Jian Hu, 2010, Cancer cell.

Creation of human tumour cells with defined genetic elements

Robert A. Weinberg, William C. Hahn, Roderick L. Beijersbergen, 1999, Nature.

AACR Cancer Progress Report 2015

Nina Bhardwaj, Ronald P. DeMatteo, William C. Hahn, 2015, Clinical Cancer Research.

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

Jill P. Mesirov, Joseph Rosenbluh, Aviad Tsherniak, 2012, Cell.

Targeted Tumor-Penetrating siRNA Nanocomplexes for Credentialing the Ovarian Cancer Oncogene ID4

Jill P. Mesirov, Justin H Lo, Erkki Ruoslahti, 2012, Science Translational Medicine.

An integrative analysis reveals functional targets of GATA6 transcriptional regulation in gastric cancer

X. Shirley Liu, Hyunjin Shin, Shuji Ogino, 2013, Oncogene.

Organoid Modeling of the Tumor Immune Microenvironment

Chiara Sabatti, Grace X. Y. Zheng, Joseph C. Liao, 2018, Cell.

CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

Sridhar Ramaswamy, Eric S. Lander, Ian F. Dunn, 2010, PloS one.

Telomerase contributes to tumorigenesis by a telomere length-independent mechanism

Robert A. Weinberg, William C. Hahn, Mark Fleming, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Synthetic Lethal Interaction between Oncogenic KRAS Dependency and STK33 Suppression in Human Cancer Cells

Sridhar Ramaswamy, D. Gary Gilliland, Pablo Tamayo, 2009, Cell.

The Bromodomain Protein Brd4 Insulates Chromatin from DNA Damage Signaling

Anne E Carpenter, Anne E. Carpenter, James E. Bradner, 2013, Nature.

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

Joseph R. Nevins, William C. Hahn, P. Todd Stukenberg, 2004, Nature Cell Biology.

Transforming Big Data into Cancer-Relevant Insight: An Initial, Multi-Tier Approach to Assess Reproducibility and Relevance

Ken Chen, Chris Sander, Olivier Gevaert, 2016, Molecular Cancer Research.

Feedback Circuit among INK4 Tumor Suppressors Constrains Human Glioblastoma Development

Webster K. Cavenee, Yonghong Xiao, Michael R. Stratton, 2008, Cancer cell.