Jonathan J. Chen

发表

Virtual high-throughput screens identifying hPK-M2 inhibitors: Exploration of model extrapolation

Jonathan J. Chen, Lyndsey N. Schmucker, Donald P. Visco, 2019, Comput. Biol. Chem..

Developing an in silico pipeline for faster drug candidate discovery: Virtual high throughput screening with the Signature molecular descriptor using support vector machine models

Jonathan J. Chen, Donald P. Visco, D. Visco, 2017 .

Identifying novel factor XIIa inhibitors with PCA-GA-SVM developed vHTS models.

Jonathan J. Chen, D. P. Visco, D. Visco, 2017, European journal of medicinal chemistry.

Biophysical and biomolecular determination of cellular age in humans

Jonathan J. Chen, Rong Fan, Denis Wirtz, 2017, Nature Biomedical Engineering.

Interfacing Inorganic Nanowire Arrays and Living Cells for Cellular Function Analysis.

Jonathan J. Chen, Rong Fan, Jonathan J Chen, 2015, Small.

Single-cell protein secretomic signatures as potential correlates to tumor cell lineage evolution and cell–cell interaction

Jonathan J. Chen, Kara Brower, Rong Fan, 2013, Front. Oncol..

Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production

Jonathan J. Chen, M. Warr, E. Passegué, 2020, bioRxiv.

Identifying new clotting factor XIa inhibitors in virtual high‐throughput screens using PCA‐GA‐SVM models and signature

Jonathan J. Chen, Lyndsey N. Schmucker, Jonathan J Chen, 2018, Biotechnology progress.

Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

Jonathan J. Chen, Pei-Hsun Wu, Jerry S. H. Lee, 2017, Nature Communications.

High-throughput secretomic analysis of single cells to assess functional cellular heterogeneity.

Yu Wu, Jie Li, Jonathan J. Chen, 2013, Analytical chemistry.

JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.

Jonathan J. Chen, Franziska Michor, Omar Abdel-Wahab, 2015, Cancer discovery.

Pharmaceutical Machine Learning: Virtual High-Throughput Screens Identifying Promising and Economical Small Molecule Inhibitors of Complement Factor C1s

Jonathan J. Chen, Lyndsey N. Schmucker, Jonathan J Chen, 2018, Biomolecules.

Single-Cell Protein Secretion Detection and Profiling.

Jonathan J. Chen, Zhuo Chen, Rong Fan, 2019, Annual review of analytical chemistry.

Identifying de‐NEDDylation inhibitors: Virtual high‐throughput screens targeting SENP8

Jonathan J. Chen, Lyndsey N. Schmucker, Jonathan J Chen, 2019, Chemical biology & drug design.

Single-Cell Cytokine Profiling to Investigate Cellular Functional Diversity in Hematopoietic Malignancies.

Jonathan J. Chen, R. Fan, Minsuk Kwak, 2016, Methods in molecular biology.

A microchip platform for interrogating tumor-macrophage paracrine signaling at the single-cell level.

Jonathan J. Chen, Kara Brower, Rong Fan, 2014, Lab on a chip.

Pharmaceutical Machine Learning: Virtual High-Throughput Screens Identifying Promising and Economical Small Molecule Inhibitors of Complement Factor C1s

Jonathan J. Chen, Lyndsey N. Schmucker, D. Visco, 2018, Biomolecules.

JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response.

Jonathan J. Chen, J. Teruya-Feldstein, O. Abdel-Wahab, 2015, Cancer discovery.

Biophysical and biomolecular determination of cellular age in humans

Jonathan J. Chen, Pei-Hsun Wu, J. Phillip, 2017, Nature Biomedical Engineering.