Spencer S. Ericksen

发表

Practical Model Selection for Prospective Virtual Screening

Anthony Gitter, Shengchao Liu, Moayad Alnammi, 2018, bioRxiv.

DBSI: DNA-binding site identifier

Julie C. Mitchell, Spencer S. Ericksen, Xiaolei Zhu, 2013, Nucleic acids research.

Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers

Sean P. Palecek, Spencer S. Ericksen, S. Palecek, 2022, Cancers.

A marine microbiome antifungal targets urgent-threat drug-resistant fungi

Spencer S. Ericksen, Doug R. Braun, Jian Peng, 2020, Science.

Multivariate chemogenomic screening prioritizes new macrofilaricidal leads

Spencer S. Ericksen, John D. Chan, Nicolas J. Wheeler, 2022, bioRxiv.

Transmembrane Segment Five Serines of the D4 Dopamine Receptor Uniquely Influence the Interactions of Dopamine, Norepinephrine, and Ro10-4548

Spencer S. Ericksen, J. Schetz, D. Cummings, 2010, Journal of Pharmacology and Experimental Therapeutics.

Microsoft Word-71781792-file00

Spencer S. Ericksen, J. Schetz, D. Cummings, 2010 .

Tandem couture: Cys-loop receptor concatamer insights and caveats.

Spencer S. Ericksen, A. J. Boileau, 2007, Molecular neurobiology.

Regiospecificity of Human Cytochrome P450 1A1-Mediated Oxidations: The Role of Steric Effects

Spencer S. Ericksen, G. Szklarz, 2005, Journal of biomolecular structure & dynamics.

Oxidative stress via inhibition of the mitochondrial electron transport and Nrf-2-mediated anti-oxidative response regulate the cytotoxic activity of plumbagin

Spencer S. Ericksen, M. Patankar, M. Skala, 2018, Scientific Reports.

Structural Determinants for High-Affinity Zolpidem Binding to GABA-A receptors

Spencer S. Ericksen, Feyza Sancar, C. Czajkowski, 2007, Molecular Pharmacology.

Tandem couture

Spencer S. Ericksen, A. J. Boileau, 2007, Molecular Neurobiology.

Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity

Spencer S Ericksen, Spencer S. Ericksen, J. Schetz, 2009, Journal of neurochemistry.

Structural Basis of Dopamine Receptor Activation

Spencer S. Ericksen, H. Weinstein, I. Moreira, 2010 .

Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid.

Spencer S. Ericksen, I. Roots, G. Szklarz, 2004, Biochemical pharmacology.

Characterization of substrate binding to cytochrome P450 1A1 using molecular modeling and kinetic analyses: case of residue 382.

Spencer S Ericksen, Spencer S. Ericksen, C. W. Fisher, 2003, Drug metabolism and disposition: the biological fate of chemicals.

Preferred Binding Orientations of Phenacetin in CYP1A1 and CYP1A2 Are Associated with Isoform-Selective Metabolism

Spencer S. Ericksen, G. Szklarz, Youbin Tu, 2012, Drug Metabolism and Disposition.

Data‐driven models for protein interaction and design

Julie C. Mitchell, Julie C Mitchell, Spencer S Ericksen, 2013, Proteins.

Associated with Isoform-selective Metabolism

Spencer S. Ericksen, G. Szklarz, Youbin Tu, 2012 .

Preferred Binding Orientations of Phenacetin in CYP 1 A 1 and 1 A 2 are Associated with Isoform-selective Metabolism

Spencer S. Ericksen, S. Ericksen, R. Deshmukh, 2012 .

The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism.

Spencer S Ericksen, Spencer S. Ericksen, C. W. Fisher, 2004, Archives of biochemistry and biophysics.

In Silico Modeling and Scoring of PROTAC-Mediated Ternary Complex Poses.

Spencer S. Ericksen, Xueqing Nie, Weiping Tang, 2021, Journal of medicinal chemistry.

Machine Learning Consensus Scoring Improves Performance Across Targets in Structure-Based Virtual Screening

Huikun Zhang, F Michael Hoffmann, Scott A Wildman, 2017, J. Chem. Inf. Model..

Bayes optimal informer sets for early‐stage drug discovery

Spencer S. Ericksen, M. Newton, A. Gitter, 2020, Biometrics.

Predicting kinase inhibitors using bioactivity matrix derived informer sets

Stephen J. Wright, Julie C. Mitchell, Anthony Gitter, 2019, bioRxiv.

Ligand Selectivity of D2 Dopamine Receptors Is Modulated by Changes in Local Dynamics Produced by Sodium Binding

Harel Weinstein, Spencer S Ericksen, Spencer S. Ericksen, 2009, Journal of Pharmacology and Experimental Therapeutics.

DBSI server: DNA binding site identifier

Julie C. Mitchell, Xiaolei Zhu, Shravan Sukumar, 2016, Bioinform..