Paavo Honkakoski

Molecular Dynamics Simulations for Human CAR Inverse Agonists

Johanna Jyrkkärinne, Jenni Küblbeck, Juha Pulkkinen, 2012, J. Chem. Inf. Model..

Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity.

Paavo Honkakoski, Kati-Sisko Vellonen, A. Urtti, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

High variability of nitrosamine metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of N‐nitrosodimethylamine and N‐nitrosodiethylamine in mice and humans

Paavo Honkakoski, H. Bartsch, M. Lang, 1993, Molecular carcinogenesis.

Insights into ligand-elicited activation of human constitutive androstane receptor based on novel agonists and three-dimensional quantitative structure-activity relationship.

Johanna Jyrkkärinne, Jenni Küblbeck, Paavo Honkakoski, 2008, Journal of medicinal chemistry.

An update on the constitutive androstane receptor (CAR)

Johanna Jyrkkärinne, Jenni Küblbeck, Paavo Honkakoski, 2013, Drug metabolism and drug interactions.

Regulation of Human Pluripotent Stem Cell-Derived Hepatic Cell Phenotype by Three-Dimensional Hydrogel Models.

Jenni Küblbeck, Paavo Honkakoski, Arto Urtti, 2016, Tissue engineering. Part A.

Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor.

Johanna Jyrkkärinne, Jenni Küblbeck, Paavo Honkakoski, 2008, Biochemical pharmacology.

Inhibition and induction of human cytochrome P450 enzymes: current status

Paavo Honkakoski, Hannu Raunio, Olavi Pelkonen, 2008, Archives of Toxicology.

The Repressed Nuclear Receptor CAR Responds to Phenobarbital in Activating the Human CYP2B6 Gene*

Paavo Honkakoski, Takeshi Kawamoto, T. Kawamoto, 1999, The Journal of Biological Chemistry.

Effects of triaryl phosphates on mouse and human nuclear receptors.

Paavo Honkakoski, Jouko Vepsäläinen, J. Palvimo, 2004, Biochemical pharmacology.

Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system.

Jing Zhang, Jenni Küblbeck, Paavo Honkakoski, 2012, Biomaterials.