Shengdar Q Tsai

发表

Open-source guideseq software for analysis of GUIDE-seq data

Martin J. Aryee, Martin J Aryee, J Keith Joung, 2016, Nature Biotechnology.

Illuminating the genome-wide activity of genome editors for safe and effective therapeutics

Shengdar Q Tsai, S. Tsai, Yong Cheng, 2018, Genome Biology.

Correction of the Crb1rd8 allele and retinal phenotype in C57BL/6N mice via TALEN-mediated homology-directed repair.

J Keith Joung, Shengdar Q Tsai, Patsy M Nishina, 2014, Investigative ophthalmology & visual science.

Highly efficient therapeutic gene editing of human hematopoietic stem cells

Chunyan Ren, Luca Pinello, Luca Biasco, 2019, Nature Medicine.

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity

David R. Liu, Jeffry D Sander, J Keith Joung, 2015, Nature Methods.

Engineering customized TALE nucleases (TALENs) and TALE transcription factors by fast ligation-based automatable solid-phase high-throughput (FLASH) assembly.

Jonathan E Foley, Jeffry D Sander, J Keith Joung, 2013, Current protocols in molecular biology.

Defining CRISPR–Cas9 genome-wide nuclease activities with CIRCLE-seq

Martin J. Aryee, Martin J Aryee, J Keith Joung, 2018, Nature Protocols.

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

Jeffry D Sander, J Keith Joung, Jeffry D. Sander, 2013, Nature Biotechnology.

Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors

Jiao Ma, James A. Gagnon, Alan Saghatelian, 2014, Science.

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells

Martin J. Aryee, Martin J Aryee, Zachary R McCaw, 2016, Nature Biotechnology.

Genome Editing: A Tool For Research and Therapy: Towards a functional understanding of variants for molecular diagnostics using genome editing

J Keith Joung, Shengdar Q Tsai, J. Joung, 2014, Nature Medicine.

FLAsH assembly of TALeNs for high-throughput genome editing

Jeffry D Sander, J Keith Joung, Jeffry D. Sander, 2022 .

Corrigendum: CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets

Martin J Aryee, J Keith Joung, Shengdar Q Tsai, 2018, Nature Methods.