Andrea Sottoriva

发表

Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

Katevan Chkhaidze, Timon Heide, Benjamin Werner, 2019, PLoS Comput. Biol..

The MOBSTER R package for tumour subclonal deconvolution from bulk DNA whole-genome sequencing data

Giulio Caravagna, Guido Sanguinetti, Trevor A. Graham, 2020, BMC Bioinformatics.

Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates

Andrea Sottoriva, Benjamin Werner, A. Sottoriva, 2018, bioRxiv.

Modeling Evolutionary Dynamics of Epigenetic Mutations in Hierarchically Organized Tumors

Simon Tavaré, Andrea Sottoriva, Louis Vermeulen, 2011, PLoS Comput. Biol..

Integrating Approximate Bayesian Computation with Complex Agent-Based Models for Cancer Research

Simon Tavaré, Andrea Sottoriva, S. Tavaré, 2010, COMPSTAT.

Model-based tumor subclonal reconstruction

Giulio Caravagna, Guido Sanguinetti, Marc J. Williams, 2019, bioRxiv.

Defining Stem Cell Dynamics in Models of Intestinal Tumor Initiation

Andrea Sottoriva, Simon Tavaré, Louis Vermeulen, 2013, Science.

Contributions to drug resistance in glioblastoma derived from malignant cells in the sub-ependymal zone.

Anestis Touloumis, Andrea Sottoriva, Simon Tavaré, 2015, Cancer research.

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories.

Arne Traulsen, Jacob G. Scott, Benjamin Werner, 2016, Cancer research.

The shaping and functional consequences of the microRNA landscape in breast cancer

Andrea Sottoriva, Yongjun Zhao, Martin Hirst, 2013, Nature.

Evolutionary dynamics of neoantigens in growing tumours

Alexander R. A. Anderson, Benjamin Werner, Marc J. Williams, 2019, bioRxiv.

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Andrea Sottoriva, Nina Tunariu, Paul Workman, 2018, Science.

Subclonal reconstruction of tumors using machine learning and population genetics

Giulio Caravagna, Guido Sanguinetti, Benjamin Werner, 2020, Nature Genetics.

Abstract 5016: The human sub-ependymal zone harbors glioblastoma precursors and represents a distinct therapeutic target.

Anestis Touloumis, John C. Marioni, Stephen J. Price, 2013 .

Single-molecule genomic data delineate patient-specific tumor profiles and cancer stem cell organization.

Andrea Sottoriva, Darryl Shibata, Simon Tavaré, 2013, Cancer research.

Between-Region Genetic Divergence Reflects the Mode and Tempo of Tumor Evolution

Andrea Sottoriva, Darryl Shibata, Trevor A Graham, 2017, Nature Genetics.

Analysis of tumour ecological balance reveals resource-dependent adaptive strategies of ovarian cancer

Andrea Sottoriva, Carlo C. Maley, Sidra Nawaz, 2019, EBioMedicine.

Measuring cancer evolution from the genome

Andrea Sottoriva, Trevor A Graham, T. Graham, 2017, The Journal of pathology.

Reply to ‘Neutral tumor evolution?’

Giulio Caravagna, Benjamin Werner, Marc J. Williams, 2018, Nature Genetics.

Exploiting evolutionary steering to induce collateral drug sensitivity in cancer

Giulio Caravagna, Benjamin Werner, Andrea Sottoriva, 2020, Nature Communications.

Microenvironmental niche divergence shapes BRCA1-dysregulated ovarian cancer morphological plasticity

Marco Punta, Cecilia Orbegoso, Andrea Sottoriva, 2018, Nature Communications.

Detecting repeated cancer evolution from multi-region tumor sequencing data

Giulio Caravagna, Guido Sanguinetti, Daniele Ramazzotti, 2018, Nature Methods.

Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine

Andrea Sottoriva, Matthew N Davies, M. Gerlinger, 2016, Trends in cancer.

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial.

Benjamin Werner, Andrea Sottoriva, Nina Tunariu, 2018, Cancer discovery.

The evolutionary landscape of colorectal tumorigenesis

Ville Mustonen, Andrea Sottoriva, Xiaowei Jiang, 2018, Nature Ecology & Evolution.

Detecting truly clonal alterations from multi-region profiling of tumours

Arne Traulsen, Benjamin Werner, Andrea Sottoriva, 2017, Scientific Reports.