Anna Waller

发表

Figure 5, Five analogues submitted to support probe SID 88095709 (CID 44640177)

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 15, Overlay of dose response curves for probe ML231 (SID 99300522, CID 3392161)

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 4, Summary of modifications for R2

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

TIGA: Target illumination GWAS analytics

Tudor I. Oprea, Lars Juhl Jensen, Anna Waller, 2020, bioRxiv.

Table 2, Continuation of SAR expansion on initial hit SID 85240370

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 5, Summary of modifications for R4

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 16, Validated hit and SAR strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 3, SAR summary for modification at R2

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Figure 6, Screening flow chart

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 5, TOR compound triage and flow chart

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Figure 6, Schematic of screen strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Provides New Insights into Integrin Conformation-sensitive Antibody Binding Real-time Analysis of Developmental Biology: Molecular Basis of Cell and

Cristian G. Bologa, Anna Waller, Liliana Halip, 2013 .

Figure 6, Hit scaffold and dose response curves illustrating selectivity for Cdc42

Cristian G. Bologa, Larry A. Sklar, J. Jacob Strouse, 2010 .

Table 3, Summary of modifications for R1

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

High‐Throughput Flow Cytometry

Tudor I. Oprea, Eric R. Prossnitz, Cristian G. Bologa, 2010 .

Figure 9, Focus of SAR expansion efforts based on primary efflux data

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

TIN-X: target importance and novelty explorer

Tudor I. Oprea, Cristian G. Bologa, Larry A. Sklar, 2017, Bioinform..

Figure 7, Validated hit resulting from the preliminary commercial SAR effort

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 1, SAR expansion on initial hit SID 85240370

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

An Overview of the Challenges in Designing, Integrating, and Delivering BARD

Tudor I. Oprea, Noel Southall, Stephan C Schürer, 2014, Journal of biomolecular screening.

Figure 8, Sequence alignment of human Rac1 and Cdc42

Tudor I. Oprea, Bruce S. Edwards, Larry A. Sklar, 2010 .

Figure 10, TORC1 bypass cell growth analysis on the probe ML231 and SID 96099781

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 2, Summary of modifications to R1

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Pharos: Collating protein information to shed light on the druggable genome

Rajarshi Guha, Tudor I. Oprea, Larry A. Sklar, 2016, Nucleic Acids Res..

TCRD and Pharos 2021: mining the human proteome for disease biology

Anton Simeonov, Tudor I. Oprea, Noel Southall, 2020, Nucleic Acids Res..

TIGA: Target illumination GWAS analytics

Christophe G. Lambert, Tudor I. Oprea, Lars Juhl Jensen, 2020, bioRxiv.

Profiling a Selective Probe for RTG Branch of Yeast TORC1 Signaling Pathway

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe

Tudor I. Oprea, Larry A. Sklar, Chad E. Schroeder, 2013, The Journal of Biological Chemistry.

An investigation of liquid carryover and sample residual for a high-throughput flow cytometer sample delivery system.

Anna Waller, Bruce S Edwards, Larry A Sklar, 2004, Analytical chemistry.

Real-time Analysis of Ternary Complex on Particles

Terry D. Foutz, Anna Waller, Larry A Sklar, 2004, Journal of Biological Chemistry.

Three small molecule pan activator families of Ras-related GTPases

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2010 .

A small molecule pan-inhibitor of Ras-superfamily GTPases with high efficacy towards Rab7

Cristian G. Bologa, Larry A. Sklar, Chad E. Schroeder, 2013 .

Detection of Intracellular Granularity Induction in Prostate Cancer Cell Lines by Small Molecules Using the HyperCyt® High-Throughput Flow Cytometry System

Tudor I. Oprea, Anna Waller, Bruce S Edwards, 2009, Journal of biomolecular screening.

Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples

Anna Waller, Susan M. Young, Mark B. Carter, 2011, Nature Protocols.

Unexplored therapeutic opportunities in the human genome

Anton Simeonov, Christian von Mering, Tudor I. Oprea, 2018, Nature Reviews Drug Discovery.

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia

Larry A. Sklar, Stuart L. Schreiber, Anna Waller, 2016, Cell.

A Potent and Selective Inhibitor of Cdc42 GTPase

Cristian G. Bologa, Larry A. Sklar, Chad E. Schroeder, 2010 .

Unexplored therapeutic opportunities in the human genome

Anton Simeonov, Christian von Mering, Tudor I. Oprea, 2018, Nature Reviews Drug Discovery.

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.

Terry D. Foutz, Tuanli Yao, Jennifer E. Golden, 2012, ACS chemical biology.