Mark B. Carter

发表

Figure 5, Five analogues submitted to support probe SID 88095709 (CID 44640177)

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 4, Screening and Hit advancement flowchart

Tudor I. Oprea, Bruce S. Edwards, Larry A. Sklar, 2013 .

Figure 15, Overlay of dose response curves for probe ML231 (SID 99300522, CID 3392161)

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 4, Summary of modifications for R2

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 2, Continuation of SAR expansion on initial hit SID 85240370

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 5, Summary of modifications for R4

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 16, Validated hit and SAR strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 3, SAR summary for modification at R2

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Figure 6, Screening flow chart

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 5, TOR compound triage and flow chart

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Figure 6, Schematic of screen strategy

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 3, Summary of modifications for R1

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 9, Focus of SAR expansion efforts based on primary efflux data

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 7, Validated hit resulting from the preliminary commercial SAR effort

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Table 1, SAR expansion on initial hit SID 85240370

Dan C. Fara, Tudor I. Oprea, Cristian G. Bologa, 2013 .

Figure 10, TORC1 bypass cell growth analysis on the probe ML231 and SID 96099781

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Table 2, Summary of modifications to R1

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry.

Susan M. Young, Mark B. Carter, T. Oprea, 2011, Assay and drug development technologies.

The Targeted Delivery of Multicomponent Cargos to Cancer Cells via Nanoporous Particle-Supported Lipid Bilayers

Mark B. Carter, Cheryl L. Willman, C. Jeffrey Brinker, 2011, Nature materials.

Cell-specific delivery of diverse cargos by bacteriophage MS2 virus-like particles.

Mark B. Carter, Genevieve K Phillips, C Jeffrey Brinker, 2011, ACS nano.

Cell-Speci fi cDelivery of Diverse Cargos byBacteriophageMS 2 Virus-likeParticles

Mark B. Carter, Eric C. Carnes, C. Brinker, 2011 .

Profiling a Selective Probe for RTG Branch of Yeast TORC1 Signaling Pathway

Tudor I. Oprea, Cristian G. Bologa, Bruce S. Edwards, 2013 .

Erratum: The targeted delivery of multicomponent cargos to cancer cells by nanoporous particle-supported lipid bilayers (Nature Materials (2011) 10 (389-397))

Mark B. Carter, Cheryl L. Willman, C. Jeffrey Brinker, 2011 .

Selective Bcl-2 Inhibitor Probes

Tudor I. Oprea, Bruce S. Edwards, Larry A. Sklar, 2013 .

Activation of Rho Family GTPases by Small Molecules

Tudor I. Oprea, Terry D. Foutz, Susan M. Young, 2018, ACS chemical biology.

Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters.

Tudor I. Oprea, Susan M. Young, Mark B. Carter, 2013, Analytical biochemistry.

High Throughput Screen for Inhibitors of Rac1 GTPase by Flow Cytometry

Mark B. Carter, David C Murray, Zhaoping Liu, 2017, Multidimensional Flow Cytometry Techniques for Novel Highly Informative Assays.

FRET detection of lymphocyte function–associated antigen-1 conformational extension

Tudor I. Oprea, Mark B. Carter, T. Oprea, 2015, Molecular biology of the cell.

The proteomics of quiescent and nonquiescent cell differentiation in yeast stationary-phase cultures

Susan M. Young, Mark B. Carter, George S. Davidson, 2011, Molecular biology of the cell.

A Pan-GTPase Inhibitor as a Molecular Probe

Jennifer E. Golden, Mark B. Carter, O. Ursu, 2015, PloS one.

Consequences of the loss of p53, RB1, and PTEN: relationship to gefitinib resistance in endometrial cancer.

Mark B. Carter, K. Leslie, L. Albitar, 2007, Gynecologic oncology.

Simultaneous in vitro molecular screening of protein-peptide interactions by flow cytometry, using six Bcl-2 family proteins as examples

Anna Waller, Susan M. Young, Mark B. Carter, 2011, Nature Protocols.

A Selective ATP-Binding Cassette Subfamily G Member 2 Efflux Inhibitor Revealed via High-Throughput Flow Cytometry

Tudor I. Oprea, Terry D. Foutz, Brooks E. Maki, 2013, Journal of biomolecular screening.

Cell-specific delivery by bacteriophage Single-molecule trapping Biofunctional quantum dots

Mark B. Carter, Eric C. Carnes, C. Brinker, 2011 .

Identification of a small molecule yeast TORC 1 inhibitor with a flow cytometry-based multiplex screen

Terry D. Foutz, Jennifer E. Golden, Susan M. Young, 2012 .

Flow cytometry for drug discovery, receptor pharmacology and high-throughput screening.

Mark B. Carter, Bruce S Edwards, Larry A Sklar, 2007, Current opinion in pharmacology.

Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen–Fluorogen Activating Protein Binding Pair

Mark B. Carter, A. Waggoner, J. Jarvik, 2016, Journal of biomolecular screening.

Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia

Mark B. Carter, Dominique R. Perez, S. Winter, 2016, Oncotarget.

ATP-Binding Cassette Sub-Family G Member 2

Hadya M. Njus, Terry D. Foutz, Brooks E. Maki, 2013 .

Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe

Tudor I. Oprea, Larry A. Sklar, Chad E. Schroeder, 2013, The Journal of Biological Chemistry.

Inhibitor and Its Use as a Molecular Probe Characterization of a Cdc 42 Protein Cell

Tudor I. Oprea, Chad E. Schroeder, Jennifer E. Golden, 2013 .

Identification of Isoxsuprine Hydrochloride as a Neuroprotectant in Ischemic Stroke through Cell-Based High-Throughput Screening

Mark B. Carter, Jeffrey F. Thompson, B. Edwards, 2014, PloS one.

Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry.

Terry D. Foutz, Tuanli Yao, Jennifer E. Golden, 2012, ACS chemical biology.

Cluster cytometry for high‐capacity bioanalysis

Steven W Graves, Mark B. Carter, Bruce S Edwards, 2012, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

High throughput flow cytometry based yeast two‐hybrid array approach for large‐scale analysis of protein‐protein interactions

Mark B. Carter, B. Edwards, L. Sklar, 2012, Cytometry. Part A : the journal of the International Society for Analytical Cytology.