Meta analysis: HPV and p16 pattern determines survival in patients with HNSCC and identifies potential new biologic subtype

[1]  R. Douglas,et al.  Human papillomavirus and oropharyngeal squamous cell carcinoma: a New Zealand cohort study , 2018, ANZ journal of surgery.

[2]  M. Delgado-Rodríguez,et al.  Systematic review and meta-analysis. , 2017, Medicina intensiva.

[3]  Erin McKean,et al.  Integration of high‐risk human papillomavirus into cellular cancer‐related genes in head and neck cancer cell lines , 2017, Head & neck.

[4]  Xiaodong Zhang,et al.  Human papillomavirus status and the relative biological effectiveness of proton radiotherapy in head and neck cancer cells , 2017, Head & neck.

[5]  Yoshiyuki Watanabe,et al.  Identification of human papillomavirus (HPV) 16 DNA integration and the ensuing patterns of methylation in HPV‐associated head and neck squamous cell carcinoma cell lines , 2017, International journal of cancer.

[6]  A. Aboussekhra,et al.  p16INK4A enhances the transcriptional and the apoptotic functions of p53 through DNA‐dependent interaction , 2017, Molecular carcinogenesis.

[7]  M. von Knebel Doeberitz,et al.  Diagnostic accuracy of p16INK4a immunohistochemistry in oropharyngeal squamous cell carcinomas: A systematic review and meta‐analysis , 2017, International journal of cancer.

[8]  Brian O'Sullivan,et al.  Head and neck cancers—major changes in the American Joint Committee on cancer eighth edition cancer staging manual , 2017, CA: a cancer journal for clinicians.

[9]  A. Jemal,et al.  Cancer statistics, 2017 , 2017, CA: a cancer journal for clinicians.

[10]  A. Olshan,et al.  Effect of HPV on head and neck cancer patient survival, by region and tumor site: A comparison of 1362 cases across three continents. , 2016, Oral oncology.

[11]  Xiao-Jun Ma,et al.  Diagnosis of HPV driven oropharyngeal cancers: Comparing p16 based algorithms with the RNAscope HPV-test. , 2016, Oral oncology.

[12]  A. Olshan,et al.  Prognostic significance of non-HPV16 genotypes in oropharyngeal squamous cell carcinoma. , 2016, Oral oncology.

[13]  C. von Buchwald,et al.  Novel nomograms for survival and progression in HPV+ and HPV- oropharyngeal cancer: a population-based study of 1,542 consecutive patients , 2016, Oncotarget.

[14]  M. Hummel,et al.  Prevalence and associated survival of high-risk HPV-related adenoid cystic carcinoma of the salivary glands. , 2016, International journal of oncology.

[15]  W. Quint,et al.  p16 overexpression in high-grade neuroendocrine carcinomas of the head and neck: potential diagnostic pitfall with HPV-related carcinomas , 2016, Virchows Archiv.

[16]  G. Descamps,et al.  Classical risk factors, but not HPV status, predict survival after chemoradiotherapy in advanced head and neck cancer patients , 2016, Journal of Cancer Research and Clinical Oncology.

[17]  C. Alexiou,et al.  Immunohistochemical Evaluation of E6/E7 HPV Oncoproteins Staining in Cervical Cancer. , 2016, Anticancer research.

[18]  Q. Wei,et al.  Squamous cell carcinoma of the oral cavity often overexpresses p16 but is rarely driven by human papillomavirus. , 2016, Oral oncology.

[19]  Kay J. Park,et al.  A Detailed Immunohistochemical Analysis of a Large Series of Cervical and Vaginal Gastric-type Adenocarcinomas , 2016, The American journal of surgical pathology.

[20]  V. Giri,et al.  High prevalence of discordant human papillomavirus and p16 oropharyngeal squamous cell carcinomas in an African American cohort , 2016, Head & neck.

[21]  M. Pawlita,et al.  From HPV-positive towards HPV-driven oropharyngeal squamous cell carcinomas. , 2016, Cancer treatment reviews.

[22]  M. Lenarz,et al.  Meta-analysis of survival in patients with HNSCC discriminates risk depending on combined HPV and p16 status , 2016, European Archives of Oto-Rhino-Laryngology.

[23]  C. Fujimoto,et al.  Prognostic value of p16 expression irrespective of human papillomavirus status in patients with oropharyngeal carcinoma. , 2015, Japanese journal of clinical oncology.

[24]  W. Weichert,et al.  Contribution of human papilloma virus to the incidence of squamous cell carcinoma of the head and neck in a European population with high smoking prevalence. , 2015, European journal of cancer.

[25]  S. Yin,et al.  Low prevalence of human papillomavirus in head and neck squamous cell carcinoma in Chinese patients , 2015, Journal of medical virology.

[26]  F. Wrba,et al.  Improved survival in HPV/p16-positive oropharyngeal cancer patients treated with postoperative radiotherapy , 2015, Strahlentherapie und Onkologie.

[27]  M. Prystowsky,et al.  Combined P16 and human papillomavirus testing predicts head and neck cancer survival , 2014, International journal of cancer.

[28]  M. Kloor,et al.  No evidence of oncogenic KRAS mutations in squamous cell carcinomas of the anogenital tract and head and neck region independent of human papillomavirus and p16(INK4a) status. , 2014, Human pathology.

[29]  S. Sanjosé,et al.  HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis. , 2014, The Lancet. Oncology.

[30]  P. Harari,et al.  p16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma. , 2014, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[31]  A. Kaufmann,et al.  Prognostic Significance of Overexpressed p16INK4a in Patients with Cervical Cancer: A Meta-Analysis , 2014, PloS one.

[32]  R. Miceli,et al.  Treatment-related outcome of oropharyngeal cancer patients differentiated by HPV dictated risk profile: a tertiary cancer centre series analysis. , 2014, Annals of oncology : official journal of the European Society for Medical Oncology.

[33]  P. Vielh,et al.  Human papillomavirus prevalence and prognostic implication in oropharyngeal squamous cell carcinomas , 2014, Head & neck.

[34]  P. Snijders,et al.  Time trends in the prevalence of HPV in oropharyngeal squamous cell carcinomas in northern Spain (1990–2009) , 2014, International journal of cancer.

[35]  A. Jemal,et al.  Cancer statistics, 2014 , 2014, CA: a cancer journal for clinicians.

[36]  P. Ramani,et al.  Risk stratification of early stage oral tongue cancers based on HPV status and p16 immunoexpression. , 2014, Asian Pacific journal of cancer prevention : APJCP.

[37]  M. Rietbergen,et al.  Human papillomavirus detection and comorbidity: critical issues in selection of patients with oropharyngeal cancer for treatment De-escalation trials. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.

[38]  P. Argani,et al.  A subset of malignant phyllodes tumors harbors alterations in the Rb/p16 pathway. , 2013, Human pathology.

[39]  G. Divine,et al.  HPV and methylation indicators in paired tumor and saliva in HNSCC , 2013 .

[40]  S. Zou,et al.  [Relationship between HPV-DNA status and p16 protein expression in oropharyngeal squamous cell carcinoma and their clinical significance]. , 2013, Zhonghua zhong liu za zhi [Chinese journal of oncology].

[41]  R. Müller,et al.  Prognostic impact of human papillomavirus status, survivin, and epidermal growth factor receptor expression on survival in patients treated with radiochemotherapy for very advanced nonresectable oropharyngeal cancer , 2013, Head & neck.

[42]  H. Mehanna,et al.  Prognostic biomarkers of survival in oropharyngeal squamous cell carcinoma: Systematic review and meta‐analysis , 2013, Head & neck.

[43]  Yun Feng,et al.  Angiotensin-converting enzyme 2 attenuates the metastasis of non-small cell lung cancer through inhibition of epithelial-mesenchymal transition. , 2013, Oncology reports.

[44]  T. Grob,et al.  HNSCC cell lines positive for HPV and p16 possess higher cellular radiosensitivity due to an impaired DSB repair capacity. , 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[45]  M. Hummel,et al.  ALDH1-positive cancer stem-like cells are enriched in nodal metastases of oropharyngeal squamous cell carcinoma independent of HPV status. , 2013, Oncology reports.

[46]  R. Newcombe,et al.  ' s response to reviews Title : Human Papillomavirus-associated oropharyngeal cancer : an observational study of diagnosis , prevalence and prognosis in a UK population , 2013 .

[47]  G. Niedobitek,et al.  Detection of HPV infection in head and neck squamous cell carcinoma: a practical proposal , 2013, Virchows Archiv.

[48]  Kyung-Ja Cho,et al.  p16 immunohistochemistry alone is a better prognosticator in tonsil cancer than human papillomavirus in situ hybridization with or without p16 immunohistochemistry , 2013, Acta oto-laryngologica.

[49]  G. Divine,et al.  Significance of p16 in Site-specific HPV Positive and HPV Negative Head and Neck Squamous Cell Carcinoma. , 2012, Cancer and clinical oncology.

[50]  P. Harari,et al.  Development and Characterization of HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinoma Tumorgrafts , 2012, Clinical Cancer Research.

[51]  Yuh-Seog Jung,et al.  Human papillomavirus in oropharyngeal squamous cell carcinomas in korea: Use of G1 cycle markers as new prognosticators , 2012, Head & neck.

[52]  M. Pawlita,et al.  Viral RNA patterns and high viral load reliably define oropharynx carcinomas with active HPV16 involvement. , 2012, Cancer research.

[53]  B. Christensen,et al.  Biomarkers of HPV in head and neck squamous cell carcinoma. , 2012, Cancer research.

[54]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[55]  K. Purdie,et al.  Clinically significant human papilloma virus in squamous cell carcinoma of the head and neck in UK practice. , 2012, Clinical oncology (Royal College of Radiologists (Great Britain)).

[56]  J.,et al.  The New England Journal of Medicine , 2012 .

[57]  Esther Kim,et al.  Human papillomavirus and rising oropharyngeal cancer incidence in the United States. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[58]  R. Gibbs,et al.  Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1 , 2011, Science.

[59]  K. Cooper,et al.  Discrimination of ‘Driver’ and ‘Passenger’ HPV in Tonsillar Carcinomas by the Polymerase Chain Reaction, Chromogenic In Situ Hybridization, and p16INK4a Immunohistochemistry , 2011, Head and neck pathology.

[60]  A. Mazo,et al.  p16Ink4a overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors , 2011, Oncogene.

[61]  K. Münger,et al.  Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming , 2011, Proceedings of the National Academy of Sciences.

[62]  W. Rittgen,et al.  p16INK4a overexpression predicts translational active human papillomavirus infection in tonsillar cancer , 2010, International journal of cancer.

[63]  J. Lee,et al.  Human papillomavirus‐active head and neck cancer and ethnic health disparities , 2010, The Laryngoscope.

[64]  K. Ang,et al.  Human papillomavirus and survival of patients with oropharyngeal cancer. , 2010, The New England journal of medicine.

[65]  D. Rickman,et al.  Biological and clinical relevance of transcriptionally active human papillomavirus (HPV) infection in oropharynx squamous cell carcinoma , 2010, International journal of cancer.

[66]  Albert C. Koong,et al.  The relationship between human papillomavirus status and other molecular prognostic markers in head and neck squamous cell carcinomas. , 2009, International journal of radiation oncology, biology, physics.

[67]  K. Knudsen,et al.  Tailoring to RB: tumour suppressor status and therapeutic response , 2008, Nature Reviews Cancer.

[68]  L. Turek,et al.  P16INK4a expression, human papillomavirus, and survival in head and neck cancer. , 2008, Oral oncology.

[69]  F. Schmidt Meta-Analysis , 2008 .

[70]  Carole Fakhry,et al.  Case-control study of human papillomavirus and oropharyngeal cancer. , 2007, The New England journal of medicine.

[71]  R. Ferris,et al.  Antitumor activity of human papillomavirus type 16 E7-specific T cells against virally infected squamous cell carcinoma of the head and neck. , 2005, Cancer research.

[72]  S. Franceschi,et al.  Human Papillomavirus Types in Head and Neck Squamous Cell Carcinomas Worldwide: A Systematic Review , 2005, Cancer Epidemiology Biomarkers & Prevention.

[73]  H. Dienes,et al.  Expression of p16 protein is associated with human papillomavirus status in tonsillar carcinomas and has implications on survival. , 2005, Advances in oto-rhino-laryngology.

[74]  L. Andersson,et al.  Impact of Fixative on Recovery of mRNA From Paraffin-Embedded Tissue , 2004, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

[75]  H. Dienes,et al.  Expression of p16 protein identifies a distinct entity of tonsillar carcinomas associated with human papillomavirus. , 2003, The American journal of pathology.

[76]  F. Bosch,et al.  Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control , 2002, Oncogene.

[77]  D. Sidransky,et al.  Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. , 2000, Journal of the National Cancer Institute.

[78]  S. Tavtigian,et al.  Complex structure and regulation of the P16 (MTS1) locus. , 1995, Cancer research.

[79]  Kopf und Halschirurgie Deutsche Gesellschaft für Hals-Nasen-Ohrenheilkunde European archives of oto-rhino-laryngology , 1990 .

[80]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.