Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing

[1]  F. Geissmann,et al.  Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors , 2014, Nature.

[2]  R. Simone,et al.  Microglial polarization and plasticity: Evidence from organotypic hippocampal slice cultures , 2013, Glia.

[3]  D. Powell,et al.  Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock , 2013, Science.

[4]  H. Boddeke,et al.  Histone deacetylase inhibitors suppress immune activation in primary mouse microglia , 2013, Journal of neuroscience research.

[5]  K. Ishii,et al.  Retinal cell type‐specific prevention of ischemia‐induced damages by LPS‐TLR4 signaling through microglia , 2013, Journal of neurochemistry.

[6]  P. Wade,et al.  Epigenetics and the adaptive immune response. , 2013, Molecular aspects of medicine.

[7]  J. Filosa,et al.  A quantitative spatiotemporal analysis of microglia morphology during ischemic stroke and reperfusion , 2013, Journal of Neuroinflammation.

[8]  C. Cunningham Microglia and neurodegeneration: The role of systemic inflammation , 2013, Glia.

[9]  Liwu Li,et al.  Molecular Mechanism Responsible for the Priming of Macrophage Activation* , 2012, The Journal of Biological Chemistry.

[10]  H. Kettenmann,et al.  Toll‐like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia , 2012, Glia.

[11]  H. Neumann,et al.  Janus-faced microglia: beneficial and detrimental consequences of microglial phagocytosis , 2012, Front. Cell. Neurosci..

[12]  F. Mormann,et al.  Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors , 2012, Journal of Neurology, Neurosurgery & Psychiatry.

[13]  H. Redmond,et al.  The emerging role of microRNA in regulation of endotoxin tolerance , 2012, Journal of leukocyte biology.

[14]  Shu‐Yi Lin,et al.  Prenatal lipopolysaccharide exposure increases anxiety-like behaviors and enhances stress-induced corticosterone responses in adult rats , 2012, Brain, Behavior, and Immunity.

[15]  S. Bilbo,et al.  Microglia and Memory: Modulation by Early-Life Infection , 2011, The Journal of Neuroscience.

[16]  C. McCall,et al.  MicroRNA‐146a regulates both transcription silencing and translation disruption of TNF‐α during TLR4‐induced gene reprogramming , 2011, Journal of leukocyte biology.

[17]  E. Chan,et al.  MicroRNA in TLR signaling and endotoxin tolerance , 2011, Cellular and Molecular Immunology.

[18]  W. Brück,et al.  CD14 and TRIF govern distinct responsiveness and responses in mouse microglial TLR4 challenges by structural variants of LPS , 2011, Brain, Behavior, and Immunity.

[19]  H. Kettenmann,et al.  Physiology of microglia. , 2011, Physiological reviews.

[20]  F. Ginhoux,et al.  Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages , 2010, Science.

[21]  F. Pitossi,et al.  Prenatal inflammation impairs adult neurogenesis and memory related behavior through persistent hippocampal TGFβ1 downregulation , 2010, Brain, Behavior, and Immunity.

[22]  P. Meerlo,et al.  Coping with sleep deprivation: shifts in regional brain activity and learning strategy. , 2010, Sleep.

[23]  G. Enikolopov,et al.  Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. , 2010, Cell stem cell.

[24]  B. Turner,et al.  Undifferentiated Embryonic Cell Transcription Factor 1 Regulates ESC Chromatin Organization and Gene Expression , 2010, Stem cells.

[25]  Y. Gotoh,et al.  Epigenetic control of neural precursor cell fate during development , 2010, Nature Reviews Neuroscience.

[26]  C. McCall,et al.  MicroRNAs Distinguish Translational from Transcriptional Silencing during Endotoxin Tolerance* , 2010, The Journal of Biological Chemistry.

[27]  Guy C. Brown,et al.  Inflammatory Neurodegeneration and Mechanisms of Microglial Killing of Neurons , 2010, Molecular Neurobiology.

[28]  S. Biswas,et al.  Endotoxin tolerance: new mechanisms, molecules and clinical significance. , 2009, Trends in immunology.

[29]  Xiaoping Chen,et al.  The NF-κB Factor RelB and Histone H3 Lysine Methyltransferase G9a Directly Interact to Generate Epigenetic Silencing in Endotoxin Tolerance* , 2009, The Journal of Biological Chemistry.

[30]  Benjamin A. Garcia,et al.  Chromatin-Specific Remodeling by HMGB1 and Linker Histone H1 Silences Proinflammatory Genes during Endotoxin Tolerance , 2009, Molecular and Cellular Biology.

[31]  G. Hawkins,et al.  G9a and HP1 Couple Histone and DNA Methylation to TNFα Transcription Silencing during Endotoxin Tolerance* , 2008, Journal of Biological Chemistry.

[32]  Thomas D. Schmittgen,et al.  Analyzing real-time PCR data by the comparative CT method , 2008, Nature Protocols.

[33]  W. Yeh,et al.  LPS/TLR4 signal transduction pathway. , 2008, Cytokine.

[34]  F. Rossi,et al.  Local self-renewal can sustain CNS microglia maintenance and function throughout adult life , 2007, Nature Neuroscience.

[35]  W. Banks,et al.  Brain-immune communication pathways , 2007, Brain, Behavior, and Immunity.

[36]  Simmie L. Foster,et al.  Gene-specific control of inflammation by TLR-induced chromatin modifications , 2007, Nature.

[37]  Dustin E. Schones,et al.  High-Resolution Profiling of Histone Methylations in the Human Genome , 2007, Cell.

[38]  N. Rothwell,et al.  Caspase-1-dependent processing of pro-interleukin-1β is cytosolic and precedes cell death , 2007, Journal of Cell Science.

[39]  T. Kouzarides Chromatin Modifications and Their Function , 2007, Cell.

[40]  T. Klockgether,et al.  Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model , 2007, Experimental Neurology.

[41]  H. Kettenmann,et al.  The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia , 2006, Molecular and Cellular Neuroscience.

[42]  Jeppe Falsig,et al.  The dynamics of the LPS triggered inflammatory response of murine microglia under different culture and in vivo conditions , 2006, Journal of Neuroimmunology.

[43]  F. Helmchen,et al.  Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo , 2005, Science.

[44]  M. Minami,et al.  Endotoxin Preconditioning Prevents Cellular Inflammatory Response During Ischemic Neuroprotection in Mice , 2004, Stroke.

[45]  A. Nicolini,et al.  Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis , 2003, Journal of neurochemistry.

[46]  William C Hahn,et al.  Lentivirus-delivered stable gene silencing by RNAi in primary cells. , 2003, RNA.

[47]  N. Rothwell,et al.  Purinergic (P2X7) Receptor Activation of Microglia Induces Cell Death via an Interleukin-1-Independent Mechanism , 2002, Molecular and Cellular Neuroscience.

[48]  C. Boucsein,et al.  Electrophysiological properties of microglial cells in normal and pathologic rat brain slices , 2000, The European journal of neuroscience.

[49]  H. Kettenmann,et al.  Microglial activation by components of gram-positive and -negative bacteria: distinct and common routes to the induction of ion channels and cytokines. , 1999, Journal of neuropathology and experimental neurology.

[50]  P. J. van den Elsen,et al.  Simvastatin reduces CCL2 expression in monocyte-derived cells by induction of a repressive CCL2 chromatin state. , 2014, Human immunology.

[51]  S. Akira,et al.  TLR signaling. , 2006, Current topics in microbiology and immunology.