Assessment of technological options and economical feasibility for cyanophycin biopolymer and high-value amino acid production

[1]  J. Sanders,et al.  Biomass in the manufacture of industrial products—the use of proteins and amino acids , 2007, Applied Microbiology and Biotechnology.

[2]  A. Steinbüchel,et al.  Analysis of genome sequences for genes of cyanophycin metabolism: identifying putative cyanophycin metabolizing prokaryotes. , 2007, Macromolecular bioscience.

[3]  Hans Mooibroek,et al.  Bio-refinery as the bio-inspired process to bulk chemicals. , 2007, Macromolecular bioscience.

[4]  Alexander Steinbüchel,et al.  Optimization of cyanophycin production in recombinant strains of Pseudomonas putida and Ralstonia eutropha employing elementary mode analysis and statistical experimental design , 2006, Biotechnology and bioengineering.

[5]  A. Steinbüchel,et al.  Application of a KDPG-aldolase gene-dependent addiction system for enhanced production of cyanophycin in Ralstonia eutropha strain H16. , 2006, Metabolic engineering.

[6]  J. Sanders,et al.  Protamylasse, a Residual Compound of Industrial Starch Production, Provides a Suitable Medium for Large-Scale Cyanophycin Production , 2005, Applied and Environmental Microbiology.

[7]  U. Conrad Polymers from plants to develop biodegradable plastics. , 2005, Trends in plant science.

[8]  W. Lockau,et al.  Production of cyanophycin, a suitable source for the biodegradable polymer polyaspartate, in transgenic plants. , 2005, Plant biotechnology journal.

[9]  A. Steinbüchel,et al.  Physiological Conditions Conducive to High Cyanophycin Content in Biomass of Acinetobacter calcoaceticus Strain ADP1 , 2005, Applied and Environmental Microbiology.

[10]  A. Steinbüchel,et al.  Microbial degradation of poly(amino acid)s. , 2004, Biomacromolecules.

[11]  A. Steinbüchel,et al.  Isolation and characterization of gram-positive cyanophycin-degrading bacteria-kinetic studies on cyanophycin depolymerase activity in aerobic bacteria. , 2004, Biomacromolecules.

[12]  B. Witholt,et al.  Expression of poly-3-(R)-hydroxyalkanoate (PHA) polymerase and acyl-CoA-transacylase in plastids of transgenic potato leads to the synthesis of a hydrophobic polymer, presumably medium-chain-length PHAs , 2004, Planta.

[13]  B. Witholt,et al.  Evidence of medium-chain-length polyhydroxyoctanoate accumulation in transgenic potato lines expressing the Pseudomonas oleovorans Pha-C1 polymerase in the cytoplasm , 2003 .

[14]  Alexander Steinbüchel,et al.  Isolation of Cyanophycin-degrading Bacteria, Cloning and Characterization of an Extracellular Cyanophycinase Gene (cphE) from Pseudomonas anguilliseptica Strain BI , 2002, The Journal of Biological Chemistry.

[15]  A. Steinbüchel,et al.  Technical-Scale Production of Cyanophycin with Recombinant Strains of Escherichia coli , 2002, Applied and Environmental Microbiology.

[16]  W. Lockau,et al.  Cyanophycin Synthetase-Like Enzymes of Non-Cyanobacterial Eubacteria: Characterization of the Polymer Produced by a Recombinant Synthetase of Desulfitobacterium hafniense , 2002, Zeitschrift fur Naturforschung. C, Journal of biosciences.

[17]  Y. Poirier Polyhydroxyalknoate synthesis in plants as a tool for biotechnology and basic studies of lipid metabolism. , 2002, Progress in lipid research.

[18]  Alexander Steinbüchel,et al.  Evaluation of non-cyanobacterial genome sequences for occurrence of genes encoding proteins homologous to cyanophycin synthetase and cloning of an active cyanophycin synthetase from Acinetobacter sp. strain DSM 587 , 2002, Archives of Microbiology.

[19]  A. Steinbüchel,et al.  Molecular Characterization of a Thermostable Cyanophycin Synthetase from the Thermophilic Cyanobacterium Synechococcus sp. Strain MA19 and In Vitro Synthesis of Cyanophycin and Related Polyamides , 2002, Applied and Environmental Microbiology.

[20]  A. Steinbüchel,et al.  Heterologous expression of cyanophycin synthetase and cyanophycin synthesis in the industrial relevant bacteria Corynebacterium glutamicum and Ralstonia eutropha and in Pseudomonas putida. , 2001, Biomacromolecules.

[21]  A. Steinbüchel,et al.  Occurrence, functions and biosynthesis of polyamides in microorganisms and biotechnological production , 2001, Naturwissenschaften.

[22]  A. Steinbüchel,et al.  Molecular characterization of the cyanophycin synthetase from Synechocystis sp. strain PCC6308 , 2000, Archives of Microbiology.

[23]  K. Baier,et al.  Biosynthesis of the cyanobacterial reserve polymer multi-L-arginyl-poly-L-aspartic acid (cyanophycin): mechanism of the cyanophycin synthetase reaction studied with synthetic primers. , 2000, European journal of biochemistry.

[24]  A. Steinbüchel,et al.  Purification and characterization of cyanophycin and cyanophycin synthetase from the thermophilic Synechococcus sp. MA19. , 1999, FEMS microbiology letters.

[25]  W. Lockau,et al.  Molecular characterization of cyanophycin synthetase, the enzyme catalyzing the biosynthesis of the cyanobacterial reserve material multi-L-arginyl-poly-L-aspartate (cyanophycin). , 1998, European journal of biochemistry.

[26]  G. Hannig,et al.  Strategies for optimizing heterologous protein expression in Escherichia coli. , 1998, Trends in biotechnology.

[27]  M. Schwamborn Chemical synthesis of polyaspartates: a biodegradable alternative to currently used polycar☐ylate homo- and copolymers , 1998 .

[28]  W. Joentgen,et al.  Chemical synthesis of polyaspartates. a biodegradable alternative to currently used polycarboxylate homo- and copolymers , 1998 .

[29]  D. Campbell,et al.  Effect of the nitrogen source on phycobiliprotein synthesis and cell reserves in a chromatically adapting filamentous cyanobacterium. , 1996, Microbiology.

[30]  S. Lee,et al.  High cell-density culture of Escherichia coli. , 1996, Trends in biotechnology.

[31]  Y. Poirier,et al.  Polyhydroxybutyrate, a Biodegradable Thermoplastic, Produced in Transgenic Plants , 1992, Science.

[32]  Geoffrey D. Smith,et al.  Transient accumulations of cyanophycin in Anabaena cylindrica and Synechocystis 6308 , 1990 .

[33]  R. Simon,et al.  THE NORMAL AND INDUCED OCCURRENCE OF CYANOPHYCIN INCLUSION BODIES IN SEVERAL BLUE‐GREEN ALGAE 1 , 1982 .

[34]  R. Simon,et al.  The normal and induced occurrence of cyanophycin inclusion bodies in several blue-green algae [Anabaena cylindrica, Beggiatoa alba, Beggiatoa leptomitiformis, Vitreoscilla beggiatoides]. , 1982 .

[35]  P. Weathers,et al.  Structure and composition of cyanophycin granules in the cyanobacterium Aphanocapsa 6308 , 1980, Journal of bacteriology.

[36]  R. Simon The biosynthesis of multi-L-arginyl-poly(L-aspartic acid) in the filamentous cyanobacterium Anabaena cylindrica. , 1976, Biochimica et biophysica acta.

[37]  P. Weathers,et al.  Determination of the structure of the novel polypeptide containing aspartic acid and arginine which is found in Cyanobacteria. , 1976, Biochimica et biophysica acta.

[38]  R. Simon Measurement of the Cyanophycin Granule Polypeptide Contained in the Blue-Green Alga Anabaena cylindrica , 1973, Journal of bacteriology.

[39]  R. Simon Cyanophycin Granules from the Blue-Green Alga Anabaena cylindrica: A Reserve Material Consisting of Copolymers of Aspartic Acid and Arginine. , 1971, Proceedings of the National Academy of Sciences of the United States of America.