Practice Patterns and Clinical Outcomes After Hybrid Coronary Revascularization in the United States: An Analysis From the Society of Thoracic Surgeons Adult Cardiac Database

Background— Hybrid coronary revascularization (HCR) involves a combination of surgical and percutaneous techniques, which in selected patients may present an alternative to conventional coronary artery bypass grafting (CABG). Methods and Results— Patients were included who underwent HCR (staged/concurrent) or isolated CABG in the Society of Thoracic Surgeons Adult Cardiac Surgery Database (July 2011 to March 2013). HCR represented 0.48% (n=950; staged=809, concurrent=141) of the total CABG volume (n=198 622) during the study period, and was performed in one-third of participating centers (n=361). Patients who underwent HCR had higher cardiovascular risk profiles in comparison with patients undergoing CABG. In comparison with CABG, median sternotomy (98.5% for CABG, 61.1% for staged HCR, and 52.5% for concurrent HCR), direct vision harvesting (98.9%, 66.0%, and 68.1%) and cardiopulmonary bypass (83.4%, 45%, and 36.9%) were less frequently used for staged and concurrent HCR, whereas robotic assistance (0.7%, 33.0%, and 30.5%) was more common. After adjustment, no differences were observed for the composite of in-hospital mortality and major morbidity (odds ratio, 0.93; 95% confidence interval, 0.75–1.16; P=0.53 for staged HCR, and odds ratio, 0.94; 95% confidence interval, 0.56–1.56; P=0.80 for concurrent HCR in comparison with CABG). There was no statistically significant association between operative mortality and either treatment group (odds ratio, 0.74; 95% confidence interval, 0.42–1.30; P=0.29 for staged HCR, and odds ratio, 2.26; 95% confidence interval, 0.99–5.17; P=0.053 for concurrent HCR in comparison with CABG). Conclusion— HCR, either as a staged or concurrent procedure, is performed in one-third of US hospitals and is reserved for a highly selected patient population. Although HCR may appear to be an equally safe alternative for CABG surgery, further randomized study is warranted.

[1]  M. Zembala,et al.  Hybrid revascularization for multivessel coronary artery disease. , 2014, JACC. Cardiovascular interventions.

[2]  Shengshou Hu,et al.  Effect of one-stop hybrid coronary revascularization on postoperative renal function and bleeding: a comparison study with off-pump coronary artery bypass grafting surgery. , 2014, The Journal of thoracic and cardiovascular surgery.

[3]  B. Kiaii,et al.  Single-stage hybrid coronary revascularization with long-term follow-up. , 2014, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[4]  R. D. de Winter,et al.  Standardizing definitions for hybrid coronary revascularization. , 2014, The Journal of thoracic and cardiovascular surgery.

[5]  T. Vassiliades,et al.  Clinical and angiographic results after hybrid coronary revascularization. , 2014, The Annals of thoracic surgery.

[6]  R. D. de Winter,et al.  Status quo of hybrid coronary revascularization for multi-vessel coronary artery disease. , 2013, The Annals of thoracic surgery.

[7]  Shengshou Hu,et al.  One-stop hybrid coronary revascularization versus coronary artery bypass grafting and percutaneous coronary intervention for the treatment of multivessel coronary artery disease: 3-year follow-up results from a single institution. , 2013, Journal of the American College of Cardiology.

[8]  G. Friedrich,et al.  Robotically Assisted Hybrid Coronary Revascularization: Does Sequence of Intervention Matter? , 2013, Innovations.

[9]  Mubashir A. Mumtaz,et al.  Comparative study of same sitting hybrid coronary artery revascularization versus off-pump coronary artery bypass in multivessel coronary artery disease. , 2012, Journal of interventional cardiology.

[10]  OttavioAlfieri,et al.  Hybrid Procedures Have Proven Clinical Utility and Are the Wave of the Future , 2012 .

[11]  O. Alfieri,et al.  Hybrid Procedures Have Proven Clinical Utility and Are the Wave of the Future , 2012, Circulation.

[12]  David X M Zhao,et al.  Do Hybrid Procedures Have Proven Clinical Utility and Are They the Wave of the Future?: Hybrid Procedures Have No Proven Clinical Utility and Are Not the Wave of the Future , 2012, Circulation.

[13]  T. Vassiliades,et al.  Hybrid coronary revascularization versus off-pump coronary artery bypass grafting for the treatment of multivessel coronary artery disease. , 2011, The Annals of thoracic surgery.

[14]  G. Lemesle,et al.  Hybrid revascularization, comprising coronary artery bypass graft with exclusive arterial conduits followed by early drug-eluting stent implantation, in multivessel coronary artery disease. , 2010, Archives of cardiovascular diseases.

[15]  Sean M. O'Brien,et al.  The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 1--coronary artery bypass grafting surgery. , 2009, The Annals of thoracic surgery.

[16]  B. Kiaii,et al.  Bivalirudin as an anticoagulant for simultaneous integrated coronary artery revascularization - a novel approach to an inherent concern. , 2009, The Canadian journal of cardiology.

[17]  John A McPherson,et al.  Routine intraoperative completion angiography after coronary artery bypass grafting and 1-stop hybrid revascularization results from a fully integrated hybrid catheterization laboratory/operating room. , 2009, Journal of the American College of Cardiology.

[18]  Richard Tran,et al.  Simultaneous hybrid coronary revascularization reduces postoperative morbidity compared with results from conventional off-pump coronary artery bypass. , 2008, The Journal of thoracic and cardiovascular surgery.

[19]  Christian Kolbitsch,et al.  Simultaneous Hybrid COronary Revascularization Using Totally Endoscopic Left Internal Mammary Artery Bypass Grafting and Placement of RapamycIN Eluting Stents in the SAme IntervenTIONal Session , 2007, Cardiology.

[20]  Peter Wilde,et al.  Integrated left small thoracotomy and angioplasty for multivessel coronary artery revascularisation , 1996, The Lancet.

[21]  Keiko Fukushima,et al.  Colour-flow imaging for detection of vesicoureteral reflux , 1996, The Lancet.