Glial Expression of the β-Amyloid Precursor Protein (APP) in Global Ischemia

[1]  G. Kreutzberg,et al.  Glial β‐amyloid precursor protein: expression in the dentate gyrus after entorhinal cortex lesion , 1994, Neuroreport.

[2]  R. Banati,et al.  Glial beta-amyloid precursor protein: expression in the dentate gyrus after entorhinal cortex lesion. , 1994 .

[3]  K. Beyreuther,et al.  Amyloid-like properties of peptides flanking the epitope of amyloid precursor protein-specific monoclonal antibody 22C11. , 1993, The Journal of biological chemistry.

[4]  G. Kreutzberg,et al.  Early and rapid de novo synthesis of Alzheimer βA4‐Amyloid precursor protein (APP) in activated microglia , 1993, Glia.

[5]  M. Lazdunski,et al.  K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[6]  J. Haines,et al.  Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. , 1993, Science.

[7]  J. D. L. Torre,et al.  Can disturbed brain microcirculation cause Alzheimer’s disease? , 1993 .

[8]  D. Stephenson,et al.  Decrease in amyloid precursor protein precedes hippocampal degeneration in rat brain following transient global ischemia , 1993, Brain Research.

[9]  P. Matsudaira,et al.  Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[10]  G. Kreutzberg,et al.  Detection of lysosomal cysteine proteinases in microglia: Flow cytometric measurement and histochemical localization of cathepsin B and L , 1993, Glia.

[11]  R. Kalaria,et al.  Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain. , 1993, Neuroreport.

[12]  D. Selkoe,et al.  Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production , 1992, Nature.

[13]  U. Schreiter-Gasser,et al.  Alzheimer beta A4-amyloid protein precursor in immunocompetent cells. , 1992, The Journal of biological chemistry.

[14]  J. Kimura,et al.  Regional accumulation of amyloid β A4 protein precursor in the gerbil brain following transient cerebral ischemia , 1992, Neuroscience Letters.

[15]  J. Weber,et al.  Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. , 1992, Science.

[16]  D. Stephenson,et al.  Amyloid precursor protein accumulates in regions of neurodegeneration following focal cerebral ischemia in the rat , 1992, Brain Research.

[17]  J. Palacios,et al.  Beta-amyloid precursor protein localization in the Golgi apparatus in neurons and oligodendrocytes. An immunocytochemical structural and ultrastructural study in normal and axotomized neurons. , 1992, Brain research. Molecular brain research.

[18]  G. Kreutzberg,et al.  Cytotoxicity of microglia , 1992, Journal of Neuroimmunology.

[19]  K. Frei,et al.  APP RNA splicing is not affected by differentiation of neurons and glia in culture , 1992, FEBS letters.

[20]  G. Kreutzberg,et al.  Spinal cord microglia in experimental allergic neuritis. Evidence for fast and remote activation. , 1992, Laboratory investigation; a journal of technical methods and pathology.

[21]  U. Schreiter-Gasser,et al.  Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells. , 1992, The Journal of biological chemistry.

[22]  K. Hossmann,et al.  Immunocytochemical Study of an Early Microglial Activation in Ischemia , 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[23]  Peter Davies,et al.  Identification of normal and pathological aging in prospectively studied nondemented elderly humans , 1992, Neurobiology of Aging.

[24]  D. Graham,et al.  βA4 amyloid protein deposition in brain after head trauma , 1991, The Lancet.

[25]  D. Selkoe,et al.  Processing of beta-amyloid precursor protein in microglia and astrocytes favors an internal localization over constitutive secretion , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[26]  H. Y. Chen,et al.  Differential APP gene expression in rat cerebral cortex, meninges, and primary astroglial, microglial and neuronal cultures , 1991, FEBS letters.

[27]  S. Hirai,et al.  Expression of APP in the early stage of brain damage , 1991, Brain Research.

[28]  J. Ulrich,et al.  Alzheimer's Disease: A Description of the Structural Lesions , 1991, Brain pathology.

[29]  C. Masters,et al.  Amyloid Precursor Protein (APP) and ΒZA4 Amyloid in the Etiology of Alzheimer's Disease: Precursor‐Product Relationships in the Derangement of Neuronal Function , 1991, Brain pathology.

[30]  G. Kreutzberg,et al.  Respiratory burst activity in brain macrophages: a flow cytometric study on cultured rat microglia , 1991, Neuropathology and applied neurobiology.

[31]  R. Tanzi,et al.  Selective induction of Kunitz-type protease inhibitor domain-containing amyloid precursor protein mRNA after persistent focal ischemia in rat cerebral cortex , 1991, Neuroscience Letters.

[32]  K. Hossmann,et al.  Immunohistochemical study of glial reaction and serum-protein extravasation in relation to neuronal damage in rat hippocampus after ischemia , 1990, Neuroscience.

[33]  B. Crain,et al.  Selective neocortical and thalamic cell death in the gerbil after transient ischemia , 1990, Neuroscience.

[34]  C. Petito,et al.  The Two Patterns of Reactive Astrocytosis in Postischemic Rat Brain , 1990, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[35]  M. Graeber,et al.  Microglia: Immune Network in the CNS , 1990, Brain pathology.

[36]  C. Finch,et al.  Relation of neuronal APP-751/APP-695 mRNA ratio and neuritic plaque density in Alzheimer's disease. , 1990, Science.

[37]  T. Tabira,et al.  Developmental and differential expression of beta amyloid protein precursor mRNAs in mouse brain. , 1990, Biochemical and biophysical research communications.

[38]  J. Kimura,et al.  Tissue-specific expression of three types of β-protein precursor mRNA: Enhancement of protease inhibitor-harboring types in Alzheimer's disease brain , 1989 .

[39]  J. Wegiel,et al.  Ultrastructural Studies of the Cells Forming Amyloid Fibers in Classical Plaques , 1989, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[40]  Robert B. Nelson,et al.  Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage , 1989, Neuron.

[41]  W. Paschen,et al.  A modified four-vessel occlusion model for inducing incomplete forebrain ischemia in rats. , 1989, Stroke.

[42]  Andreas Weidemann,et al.  Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein , 1989, Cell.

[43]  P. Mcgeer,et al.  Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR , 1987, Neuroscience Letters.

[44]  G. Kreutzberg,et al.  Lectin binding by resting and reactive microglia , 1987, Journal of neurocytology.

[45]  J. Brierley,et al.  A New Model of Bilateral Hemispheric Ischemia in the Unanesthetized Rat , 1979, Stroke.

[46]  A. Alzheimer.  über eigenartige Krankheitsfälle des späteren Alters , 1911 .