Somatic mutations affect key pathways in lung adenocarcinoma
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Brian H. Dunford-Shore | T. Fennell | K. Cibulskis | S. Gabriel | E. Lander | R. Fulton | G. Weinstock | E. Mardis | R. Gibbs | G. Getz | M. Meyerson | L. Fulton | J. Baldwin | M. Zody | H. Varmus | M. Morgan | S. Scherer | A. Sabo | O. Hall | Yiming Zhu | Yanru Ren | Jiqiang Yao | A. Hawes | S. Jhangiani | M. Gonzalez-Garay | A. Milosavljevic | D. Wheeler | C. Sougnez | L. Ziaugra | R. Onofrio | L. Ding | M. McLellan | D. Larson | Xiaoqi Shi | R. Abbott | Ken Chen | D. Koboldt | M. Wendl | R. Meyer | Yuzhu Tang | Ling Lin | John R. Osborne | T. Miner | C. Pohl | C. Haipek | Heather K. Schmidt | T. Vickery | D. Dooling | W. Winckler | M. Lawrence | B. Weir | M. Ladanyi | P. Good | B. Ozenberger | Qunyuan Zhang | Xiaojun Zhao | M. Spitz | G. Tonon | D. Beer | T. Giordano | M. Orringer | H. Greulich | Hua Shen | L. Lewis | T. Mathew | Kerstin Clerc | G. Metcalf | Brian Y. Ng | G. Fewell | A. Kraja | S. Crosby | Sacha N Sander | J. Robinson | L. Chirieac | A. Dutt | M. Hanna | Roman K. Thomas | J. Roth | I. Wistuba | A. Chang | M. Watson | S. Broderick | A. Yoshizawa | W. Travis | W. Pao | M. Province | Ginger A. Fewell | B. Johnson | Christopher Sawyer | R. Wilson | D. Muzny
[1] M. Meyerson,et al. Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients , 2008, British Journal of Cancer.
[2] W. Gerald,et al. Lung Adenocarcinoma: Modification of the 2004 WHO Mixed Subtype to Include the Major Histologic Subtype Suggests Correlations Between Papillary and Micropapillary Adenocarcinoma Subtypes, EGFR Mutations and Gene Expression Analysis , 2008, The American journal of surgical pathology.
[3] Antonio Marchetti,et al. Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung , 2008, Human mutation.
[4] Daniel F. Gudbjartsson,et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease , 2008, Nature.
[5] S. Heath,et al. A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25 , 2008, Nature.
[6] Derek Y. Chiang,et al. Characterizing the cancer genome in lung adenocarcinoma , 2007, Nature.
[7] A. Sparks,et al. The Genomic Landscapes of Human Breast and Colorectal Cancers , 2007, Science.
[8] M. Mohammadi,et al. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. , 2007, Molecular cell.
[9] Tomoki Yokoyama,et al. Nras and Kras mutation in Japanese lung cancer patients: Genotyping analysis using LightCycler. , 2007, Oncology reports.
[10] Spyro Mousses,et al. A transforming mutation in the pleckstrin homology domain of AKT1 in cancer , 2007, Nature.
[11] D. Gutmann,et al. Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes. , 2007, Cancer research.
[12] R. Wilson,et al. Mutational Analysis of EGFR and Related Signaling Pathway Genes in Lung Adenocarcinomas Identifies a Novel Somatic Kinase Domain Mutation in FGFR4 , 2007, PloS one.
[13] V. McKusick. Mendelian Inheritance in Man and Its Online Version, OMIM , 2007, The American Journal of Human Genetics.
[14] E. Birney,et al. Patterns of somatic mutation in human cancer genomes , 2007, Nature.
[15] Janakiraman Subramanian,et al. Lung cancer in never smokers: a review. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] G. Parmigiani,et al. The Consensus Coding Sequences of Human Breast and Colorectal Cancers , 2006, Science.
[17] J. Brahmer,et al. Adjuvant treatment in non-small cell lung cancer: Where are we now? , 2006, Journal of the National Comprehensive Cancer Network : JNCCN.
[18] Yun-Chul Hong,et al. Genetic polymorphisms of ataxia telangiectasia mutated affect lung cancer risk. , 2006, Human molecular genetics.
[19] M. Stratton,et al. COSMIC 2005 , 2006, British Journal of Cancer.
[20] Andrew D. Yates,et al. Somatic mutations of the protein kinase gene family in human lung cancer. , 2005, Cancer research.
[21] M. Meyerson,et al. Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. , 2005, Cancer research.
[22] P. Hainaut,et al. TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers. , 2005, Cancer research.
[23] Elisabeth Brambilla,et al. The 2004 World Health Organization classification of lung tumors. , 2005, Seminars in roentgenology.
[24] J. Ferlay,et al. Global Cancer Statistics, 2002 , 2005, CA: a cancer journal for clinicians.
[25] M. Meyerson,et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. , 2005, The New England journal of medicine.
[26] H. Varmus,et al. Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain , 2005, PLoS medicine.
[27] H. Varmus,et al. KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib , 2005, PLoS medicine.
[28] Andrew D. Yates,et al. Athletics: Momentous sprint at the 2156 Olympics? , 2004, Nature.
[29] R. Wilson,et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[30] David J. Chen,et al. Role of DNA-PK in the cellular response to DNA double-strand breaks. , 2004, DNA repair.
[31] S. Gabriel,et al. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy , 2004, Science.
[32] K. Chin,et al. Frequent Silencing of Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B) Expression by Genetic and Epigenetic Mechanisms in Esophageal Squamous Cell Carcinoma , 2004, Cancer Research.
[33] Patricia L. Harris,et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. , 2004, The New England journal of medicine.
[34] M. Kurrer,et al. APC mutations are infrequent but present in human lung cancer. , 2004, Cancer letters.
[35] Nicole Benoit,et al. p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study. , 2003, Journal of the National Cancer Institute.
[36] Christian A. Rees,et al. Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[37] David Sidransky,et al. Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung. , 2002, Cancer research.
[38] A. Nicholson,et al. Mutations of the BRAF gene in human cancer , 2002, Nature.
[39] J. Minna,et al. LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines. , 2000, Cancer research.
[40] T. Halazonetis,et al. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. , 2000, Genes & development.
[41] S. Hecht,et al. Tobacco smoke carcinogens and lung cancer. , 1999, Journal of the National Cancer Institute.
[42] R. Brezinschek,et al. Mutation analysis of the PTEN/MMAC1 gene in lung cancer , 1998, Oncogene.
[43] J. Barrett,et al. Homozygous deletions at chromosome 9p21 and mutation analysis of p16 and p15 in microdissected primary non-small cell lung cancers. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[44] T. Sellers,et al. Evidence for mendelian inheritance in the pathogenesis of lung cancer. , 1990, Journal of the National Cancer Institute.
[45] P. O'Connell,et al. A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations , 1990, Cell.
[46] J. Minna,et al. p53: a frequent target for genetic abnormalities in lung cancer. , 1989, Science.
[47] S. Rodenhuis,et al. Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung. , 1988, Cancer research.
[48] R. Weinberg,et al. Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[49] Yang Wei-we,et al. A Review on , 2008 .
[50] T. Sellers,et al. Environmental factors can confound identification of a major gene effect: Results from a segregation analysis of a simulated population of lung cancer families , 1998, Genetic epidemiology.
[51] K. Münger,et al. Oncoproteins encoded by the cancer-associated human papillomaviruses target the products of the retinoblastoma and p53 tumor suppressor genes. , 1991, Cold Spring Harbor symposia on quantitative biology.
[52] N. Dobbs,et al. Br. J. Cancer '." , 2022 .