Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers
暂无分享,去创建一个
D. Scholtens | C. Horbinski | M. Drumm | Makda Zewde | D. Unruh | A. Tran | Adam Buss | A. Buss
[1] C. James,et al. Methylation-dependent Tissue Factor Suppression Contributes to the Reduced Malignancy of IDH1-mutant Gliomas , 2018, Clinical Cancer Research.
[2] G. Pfeifer. Defining Driver DNA Methylation Changes in Human Cancer , 2018, International journal of molecular sciences.
[3] M. Mikuła,et al. IDH1/2 Mutations Predict Shorter Survival in Chondrosarcoma , 2018, Journal of Cancer.
[4] C. Perou,et al. The association between copy number aberration, DNA methylation and gene expression in tumor samples , 2018, Nucleic acids research.
[5] Pedro P. Rocha,et al. Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2. , 2017, Cell reports.
[6] C. Marosi,et al. Correlation of immune phenotype with IDH mutation in diffuse glioma , 2017, Neuro-oncology.
[7] A. M. Houghton,et al. Mutant IDH1 regulates the tumor-associated immune system in gliomas , 2017, Genes & development.
[8] J. Costello,et al. Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas , 2017, The Journal of clinical investigation.
[9] Peter W. Laird,et al. Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes , 2016, Nucleic acids research.
[10] D. Kondziolka,et al. Mutant IDH1 and thrombosis in gliomas , 2016, Acta Neuropathologica.
[11] A. Jeltsch,et al. Allosteric control of mammalian DNA methyltransferases – a new regulatory paradigm , 2016, Nucleic acids research.
[12] Gary D. Bader,et al. AutoAnnotate: A Cytoscape app for summarizing networks with semantic annotations , 2016, F1000Research.
[13] G. Reifenberger,et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary , 2016, Acta Neuropathologica.
[14] J. Engh,et al. IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression. , 2016, Neuro-oncology.
[15] Gianluca Bontempi,et al. TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data , 2015, Nucleic acids research.
[16] [World Health Organization classification of tumours of the central nervous system: a summary]. , 2016, Zhonghua bing li xue za zhi = Chinese journal of pathology.
[17] Gianluca Bontempi,et al. TCGA Workflow: Analyze cancer genomics and epigenomics data using Bioconductor packages. , 2016, F1000Research.
[18] Gwendolyn M. Jang,et al. Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. , 2015, Cell host & microbe.
[19] Darrell,et al. Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma. , 2015, The oncologist.
[20] K. Ross,et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer , 2014, Nature.
[21] D. Brat,et al. PDGFRA Amplification is Common in Pediatric and Adult High‐Grade Astrocytomas and Identifies a Poor Prognostic Group in IDH1 Mutant Glioblastoma , 2013, Brain pathology.
[22] M. Ross,et al. Meta-analysis of IDH-mutant cancers identifies EBF1 as an interaction partner for TET2 , 2013, Nature Communications.
[23] C. Horbinski. What do we know about IDH1/2 mutations so far, and how do we use it? , 2013, Acta Neuropathologica.
[24] Derek Y. Chiang,et al. Mutations in Isocitrate Dehydrogenase 1 and 2 Occur Frequently in Intrahepatic Cholangiocarcinomas and Share Hypermethylation Targets with Glioblastomas , 2012, Oncogene.
[25] G. Reifenberger,et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics , 2012, Nature.
[26] A. Viale,et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype , 2012, Nature.
[27] S. Berger,et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation , 2012, Nature.
[28] Y. Benjamini,et al. Summarizing and correcting the GC content bias in high-throughput sequencing , 2012, Nucleic acids research.
[29] Zhujun Wang,et al. Prognostic significance of IDH1 mutations in acute myeloid leukemia: a meta-analysis. , 2012, American journal of blood research.
[30] Jeffrey W. Clark,et al. Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping. , 2012, The oncologist.
[31] K. Gunderson,et al. High density DNA methylation array with single CpG site resolution. , 2011, Genomics.
[32] A. Grigoriadis,et al. IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours , 2011, The Journal of pathology.
[33] Helga Thorvaldsdóttir,et al. Molecular signatures database (MSigDB) 3.0 , 2011, Bioinform..
[34] T. Shibata,et al. Mutant IDH1 confers an in vivo growth in a melanoma cell line with BRAF mutation. , 2011, The American journal of pathology.
[35] Reid F. Thompson,et al. Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis , 2011, PLoS genetics.
[36] Hai Yan,et al. 2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP+-Dependent Isocitrate Dehydrogenase Mutations , 2011, PloS one.
[37] J. Licht,et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. , 2010, Cancer cell.
[38] Gary D Bader,et al. Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation , 2010, PloS one.
[39] R. McLendon,et al. IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain. , 2010, Biochemical and biophysical research communications.
[40] R. Wilson,et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. , 2010, Cancer cell.
[41] Jih-Luh Tang,et al. Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation. , 2010, Blood.
[42] Mark D. Robinson,et al. edgeR: a Bioconductor package for differential expression analysis of digital gene expression data , 2009, Bioinform..
[43] R. McLendon,et al. IDH1 and IDH2 mutations in gliomas. , 2009, The New England journal of medicine.
[44] L. Liau,et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate , 2009, Nature.
[45] Ken Chen,et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. , 2009, The New England journal of medicine.
[46] P. Kleihues,et al. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. , 2009, The American journal of pathology.
[47] J. Visvader,et al. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions , 2008, Nature Reviews Cancer.
[48] D. Busam,et al. An Integrated Genomic Analysis of Human Glioblastoma Multiforme , 2008, Science.
[49] B. Scheithauer,et al. The 2007 WHO classification of tumours of the central nervous system , 2007, Acta Neuropathologica.
[50] Peter A. Jones,et al. The Epigenomics of Cancer , 2007, Cell.
[51] G. Parmigiani,et al. The Consensus Coding Sequences of Human Breast and Colorectal Cancers , 2006, Science.
[52] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[53] L. Herzenberg,et al. DNA methylation prevents the amplification of TROP1, a tumor-associated cell surface antigen gene. , 1994, Proceedings of the National Academy of Sciences of the United States of America.