No evidence for germline mutations of the LKB1/STK11 gene in familial pancreatic carcinoma.

[1]  R. Houlston,et al.  Further observations on LKB1/STK11 status and cancer risk in Peutz–Jeghers syndrome , 2003, British Journal of Cancer.

[2]  E. Montgomery,et al.  Loss of Stk11/Lkb1 Expression in Pancreatic and Biliary Neoplasms , 2003, Modern Pathology.

[3]  D. Bartsch Familial pancreatic cancer , 2003, The British journal of surgery.

[4]  K. Hemminki,et al.  Familial and second primary pancreatic cancers: A nationwide epidemiologic study from Sweden , 2003, International journal of cancer.

[5]  A. Ziegler,et al.  BRCA2 germline mutations in familial pancreatic carcinoma. , 2003, Journal of the National Cancer Institute.

[6]  Matthias Rothmund,et al.  CDKN2A Germline Mutations in Familial Pancreatic Cancer , 2002, Annals of surgery.

[7]  R. DePinho,et al.  Pancreatic cancer biology and genetics , 2002, Nature Reviews Cancer.

[8]  T. Beaty,et al.  Evidence for a major gene influencing risk of pancreatic cancer , 2002, Genetic epidemiology.

[9]  Kathleen M Murphy,et al.  Evaluation of candidate genes MAP2K4, MADH4, ACVR1B, and BRCA2 in familial pancreatic cancer: deleterious BRCA2 mutations in 17%. , 2002, Cancer research.

[10]  A. Ziegler,et al.  German National Case Collection of Familial Pancreatic Cancer – Clinical-Genetic Analysis of the First 21 Families , 2002, Oncology Research and Treatment.

[11]  A. Ziegler,et al.  Update of Familial Pancreatic Cancer in Germany , 2001, Pancreatology.

[12]  G. Thomas,et al.  Peutz-Jeghers families unlinked toSTK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma , 2001, Journal of medical genetics.

[13]  R. Hruban,et al.  Prevention of Pancreatic Cancer and Strategies for Management of Familial Pancreatic Cancer , 2001, Digestive Diseases.

[14]  J. Cameron,et al.  Increased risk of incident pancreatic cancer among first-degree relatives of patients with familial pancreatic cancer. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

[15]  S. Goodman,et al.  Very high risk of cancer in familial Peutz-Jeghers syndrome. , 2000, Gastroenterology.

[16]  G. Schackert,et al.  Frequent Loss of Heterozygosity at the 19p13.3 Locus Without LKB1/STK11 Mutations in Human Carcinoma Metastases to the Brain , 2000, Journal of Neuro-Oncology.

[17]  D. Whitcomb,et al.  Genetic testing. Counseling, laboratory, and regulatory issues and the EUROPAC protocol for ethical research in multicenter studies of inherited pancreatic diseases. , 2000, The Medical clinics of North America.

[18]  R. Hruban,et al.  Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. , 1999, The American journal of pathology.

[19]  A. Hemminki The molecular basis and clinical aspects of Peutz-Jeghers syndrome , 1999, Cellular and Molecular Life Sciences CMLS.

[20]  P. Guldberg,et al.  Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma , 1999, Oncogene.

[21]  L. Aaltonen,et al.  LKB1 somatic mutations in sporadic tumors. , 1999, The American journal of pathology.

[22]  L. Aaltonen,et al.  Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors. , 1998, Cancer research.

[23]  M. Stratton,et al.  A serine/threonine kinase gene defective in Peutz–Jeghers syndrome , 1998, Nature.

[24]  E. Dimagno,et al.  Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group. , 1997, Journal of the National Cancer Institute.

[25]  L. Tryggvadottir,et al.  Neoplastic diseases in families of breast cancer patients. , 1994, Journal of medical genetics.

[26]  C. Boland,et al.  Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. , 1993, Gastroenterology.

[27]  F. Giardiello,et al.  The risk of upper gastrointestinal cancer in familial adenomatous polyposis. , 1992, Gastroenterology.

[28]  H. Lynch,et al.  Pancreatic Cancer and the Familial Atypical Multiple Mole Melanoma (FAMMM) Syndrome , 1991, Pancreas.

[29]  R. Fitzgibbons,et al.  Familial pancreatic cancer (Part 1): Genetic pathology review. , 1989, The Nebraska medical journal.

[30]  A J Krush,et al.  Increased risk of cancer in the Peutz-Jeghers syndrome. , 1987, The New England journal of medicine.

[31]  D. Krewski,et al.  Epidemiology of pancreatic cancer: an overview. , 2003, Cancer detection and prevention.

[32]  Alicia Samuels,et al.  Cancer Statistics, 2003 , 2003, CA: a cancer journal for clinicians.

[33]  S. Kern,et al.  Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma–pancreatic carcinoma–prone families , 2002, Cancer.

[34]  R. Hruban,et al.  Progress in cancer genetics: lessons from pancreatic cancer. , 1999, Annals of oncology : official journal of the European Society for Medical Oncology.

[35]  L. Aaltonen,et al.  Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer. , 1999, Human molecular genetics.

[36]  R. Hruban,et al.  Familial pancreatic cancer. , 1999, Annals of oncology : official journal of the European Society for Medical Oncology.

[37]  J. Nezu,et al.  Peutz-Jeghers syndrome is caused by mutations in a novel serine threoninekinase , 1998, Nature Genetics.

[38]  C. Moskaluk,et al.  Novel germline p16INK4 allele (Asp145Cys) in a family with multiple pancreatic carcinomas , 1998 .

[39]  C. Moskaluk,et al.  Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online. , 1998, Human mutation.