Changes of laboratory variables with time in cirrhosis: Prognostic and therapeutic significance

The time change of laboratory variables in cirrhosis was studied by analysis of data from 488 patients with cirrhosis included in a controlled clinical trial of long‐term prednisone vs. placebo.

[1]  E. Christensen,et al.  Clinical relevance of restrictive morphological criteria for the diagnosis of cirrhosis in liver biopsies. , 2008, Liver.

[2]  L. Elveback,et al.  Clinical, biochemical, and histological remission of severe chronic active liver disease: a controlled study of treatments and early prognosis. , 1972, Gastroenterology.

[3]  W. Burnett.  An Assessment of the Value of Serum Cholinesterase as a Liver Function Test and in the Diagnosis of Jaundice , 1960, Gut.

[4]  S. Sherlock,et al.  Effect of corticosteroid therapy on bromsulphthalein excretion in active chronic hepatitis. , 1968, Gut.

[5]  A. Hunt,et al.  Serum Albumin, Pseudocholinesterase, and Transaminases in the Assessment of Liver Function Before and After Venous Shunt Operations * , 1960, Gut.

[6]  Satterthwaite Fe.  An approximate distribution of estimates of variance components. , 1946 .

[7]  C. Blackburn,et al.  Active chronic hepatitis. , 1970, The American journal of medicine.

[8]  A. Fauci,et al.  Glucocorticosteroid therapy: mechanisms of action and clinical considerations. , 1976, Annals of internal medicine.

[9]  M. Friedman,et al.  EFFECTS OF CORTISONE ON LIPID AND CHOLESTEROL METABOLISM IN THE RABBIT AND RAT. , 1965, The American journal of physiology.

[10]  A. Fauci,et al.  Comparison of agents producing a neutrophilic leukocytosis in man. Hydrocortisone, prednisone, endotoxin, and etiocholanolone. , 1975, The Journal of clinical investigation.

[11]  H. Wulff,et al.  Rational diagnosis and treatment. , 1986, The Journal of medicine and philosophy.

[12]  S. Sherlock,et al.  Controlled prospective trial of corticosteroid therapy in active chronic hepatitis. , 1971, The Quarterly journal of medicine.

[13]  D. Adlersberg,et al.  Development of hypercholesteremia during cortisone and ACTH therapy. , 1950, Journal of the American Medical Association.

[14]  H. Strauss,et al.  Effects of Corticosteroids on Coagulation of the Blood , 1962, Nature.

[15]  H. Conn.  Steroid treatment of alcoholic hepatitis , 1978 .

[16]  E. Christensen,et al.  Main causes of death in cirrhosis. , 1983, Scandinavian journal of gastroenterology.

[17]  C. Craddock.  Corticosteroid-induced lymphopenia, immunosuppression, and body defense. , 1978, Annals of internal medicine.

[18]  P. Andersen,et al.  A therapeutic index that predicts the individual effects of prednisone in patients with cirrhosis. , 1985, Gastroenterology.

[19]  D. David,et al.  Adrenal glucocorticoids after twenty years. A review of their clinically relevant consequences. , 1970, Journal of chronic diseases.

[20]  N Tygstrup,et al.  Prognostic Factors in Cirrhosis Identified by Cox's Regression Model , 2007, Hepatology.

[21]  H. Conn.  Steroid treatment of alcoholic hepatitis. The yeas and the nays. , 1978, Gastroenterology.

[22]  H. E. Weimer,et al.  Effects of corticosteroid administration on the serum electrophoretic patterns of patients with pulmonary tuberculosis. , 1961, Journal of Laboratory and Clinical Medicine.

[23]  S. S. Schreiber,et al.  Albumin synthesis. 1. , 1972, The New England journal of medicine.

[24]  E. Christensen,et al.  Prognostic Value of Child‐Turcotte Criteria in Medically Treated Cirrhosis , 1984, Hepatology.

[25]  R. Aach.  Corticosteroids and bilirubin metabolism. , 1969, Gastroenterology.

[26]  R. Stern,et al.  Controlled trial of prednisone and azathioprine in active chronic hepatitis. , 1973, Lancet.

[27]  L. Powell,et al.  Corticosteroids in liver disease: possible mechanisms of action, pharmacology, and rational use. , 1979, Gut.