论文信息 - Determination of the Absolute Configuration of (+)-Xestoaminol C [(2S, 3R)-2-Amino-3-tetradecanol], a Metabolite of Fiji Sponge, Xestospongia sp., by the Synthesis of Its… - 字舞流文

Determination of the Absolute Configuration of (+)-Xestoaminol C [(2S, 3R)-2-Amino-3-tetradecanol], a Metabolite of Fiji Sponge, Xestospongia sp., by the Synthesis of Its…

The N,O-diacetyl derivative of (+)-xestoaminol C (2-amino-3-tetradecanol, 1), an inhibitor of reverse transcriptase isolated from Xestospongia sp., was synthesized from (S)-alanine, and its absolute configuration was determined as 2S, 3R.

K. Mori | M. Ichihashi

[1] M. Bols,et al. Garner's aldehyde , 2002 .

[2] M. Garson,et al. Antifungal alkyl amino alcohols from the tropical marine sponge Haliclona n. sp. , 2001, Journal of natural products.

[3] N. Langlois. Diastereospecific formal synthesis of (2R,3S)-2-amino-tetradeca-5,7-dien-3-ol isolated from Xestospongia sp. , 2001 .

[4] S. Naranjo,et al. Obscuraminols, new unsaturated amino alcohols from the tunicate Pseudodistoma obscurum: structure and absolute configuration , 2001 .

[5] K. Mori,et al. Synthesis of sphingosine relatives. Part 19.1 Synthesis ofpenaresidin A and B, azetidine alkaloids with actomyosinATPase-activating properties , 1997 .

[6] R. Sakai,et al. Crucigasterins, new polyunsaturated amino alcohols from the mediterranean tunicate Pseudodistoma crucigaster , 1993 .

[7] K. Mori,et al. Synthesis of Sphingosine Relatives, XII Synthesis and Absolute Configuration of the Two Epimeric Aliphatic Amino Alcohols [5E, 7E)-2-Amino-5,7-tetradecadien-3-ols] Isolated from a Sponge, Xestospongia sp. , 1992 .

[8] P. Crews,et al. Novel marine sponge amino acids, 10. Xestoaminols from Xestospongia sp. , 1990, Journal of natural products.

[9] P. Scheuer,et al. Two epimeric aliphatic amino alcohols from a sponge, Xestospongia sp , 1989 .