Control of Peroxisome Proliferator-Activated Receptor γ2 Stability and Activity by SUMOylation

[1]  R. Deshaies,et al.  Diverse roles for ubiquitin-dependent proteolysis in transcriptional activation , 2003, Nature Cell Biology.

[2]  E. Milgrom,et al.  Sumoylation of the Progesterone Receptor and of the Steroid Receptor Coactivator SRC-1* , 2003, The Journal of Biological Chemistry.

[3]  J. Iñiguez-Lluhí,et al.  A Synergy Control Motif within the Attenuator Domain of CCAAT/Enhancer-binding Protein α Inhibits Transcriptional Synergy through Its PIASy-enhanced Modification by SUMO-1 or SUMO-3* , 2003, The Journal of Biological Chemistry.

[4]  M. Nakao,et al.  The Aryl Hydrocarbon Receptor Nuclear Transporter Is Modulated by the SUMO-1 Conjugation System* , 2002, The Journal of Biological Chemistry.

[5]  O. Jänne,et al.  Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor. , 2002, The Biochemical journal.

[6]  Peter F. Johnson,et al.  Transcriptional Activity of CCAAT/Enhancer-binding Proteins Is Controlled by a Conserved Inhibitory Domain That Is a Target for Sumoylation* , 2002, The Journal of Biological Chemistry.

[7]  K. Horwitz,et al.  The Inhibitory Function in Human Progesterone Receptor N Termini Binds SUMO-1 Protein to Regulate Autoinhibition and Transrepression* , 2002, The Journal of Biological Chemistry.

[8]  D. Michel,et al.  Potentiation of glucocorticoid receptor transcriptional activity by sumoylation. , 2002, Endocrinology.

[9]  D. DeFranco,et al.  Proteasomal Inhibition Enhances Glucocorticoid Receptor Transactivation and Alters Its Subnuclear Trafficking , 2002, Molecular and Cellular Biology.

[10]  J. Stephens,et al.  Interferon-γ-mediated Activation and Ubiquitin-Proteasome-dependent Degradation of PPARγ in Adipocytes* , 2002, The Journal of Biological Chemistry.

[11]  Y. Mo,et al.  Nucleolar Delocalization of Human Topoisomerase I in Response to Topotecan Correlates with Sumoylation of the Protein* , 2002, The Journal of Biological Chemistry.

[12]  B. Spiegelman,et al.  PPARγ: a Nuclear Regulator of Metabolism, Differentiation, and Cell Growth* , 2001, The Journal of Biological Chemistry.

[13]  M. Hochstrasser.  SP-RING for SUMO New Functions Bloom for a Ubiquitin-like Protein , 2001, Cell.

[14]  Z. Nawaz,et al.  Importance of the regulation of nuclear receptor degradation. , 2001, Frontiers in bioscience : a journal and virtual library.

[15]  R. Hay,et al.  SUMO-1 Conjugation in Vivo Requires Both a Consensus Modification Motif and Nuclear Targeting* , 2001, The Journal of Biological Chemistry.

[16]  S. Jentsch,et al.  Ubiquitin and proteasomes: Sumo, ubiquitin's mysterious cousin , 2001, Nature Reviews Molecular Cell Biology.

[17]  J. Palvimo,et al.  Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[18]  J. Iñiguez-Lluhí,et al.  A Common Motif within the Negative Regulatory Regions of Multiple Factors Inhibits Their Transcriptional Synergy , 2000, Molecular and Cellular Biology.

[19]  B. Spiegelman,et al.  Degradation of the Peroxisome Proliferator-activated Receptor γ Is Linked to Ligand-dependent Activation* , 2000, The Journal of Biological Chemistry.

[20]  J. Auwerx,et al.  PPARγ3 mRNA: a distinct PPARγ mRNA subtype transcribed from an independent promoter , 1998 .

[21]  T. Willson,et al.  Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ , 1998, Nature.

[22]  J. Flier,et al.  Ligand-independent activation domain in the N terminus of peroxisome proliferator-activated receptor gamma (PPARgamma). Differential activity of PPARgamma1 and -2 isoforms and influence of insulin. , 1997, The Journal of biological chemistry.

[23]  J. Auwerx,et al.  The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene* , 1997, The Journal of Biological Chemistry.

[24]  E. Kalkhoven,et al.  AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors , 1997, Molecular and cellular biology.

[25]  B. Spiegelman,et al.  15-Deoxy-Δ 12,14-Prostaglandin J 2 is a ligand for the adipocyte determination factor PPARγ , 1995, Cell.

[26]  B. Spiegelman,et al.  mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer. , 1994, Genes & development.

[27]  U. K. Laemmli,et al.  Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4 , 1970, Nature.

[28]  B. Spiegelman,et al.  Molecular regulation of adipogenesis. , 2000, Annual review of cell and developmental biology.

[29]  F. Melchior,et al.  SUMO--nonclassical ubiquitin. , 2000, Annual review of cell and developmental biology.