MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosis
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Yan Liu | Yan Yang | Aiguo Liu | Lianbo Li | Q. Hu | H. Xiong | Xudong Wang | J. Xia | D. Gurbani | Junjie Sun | Li-li Ding
[1] P. Newsholme,et al. Cancer stem cell metabolism: a potential target for cancer therapy , 2016, Molecular Cancer.
[2] Alex Boussioutas,et al. Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients , 2016, Oncotarget.
[3] X. Chen,et al. Tumor-suppressive miR-218-5p inhibits cancer cell proliferation and migration via EGFR in non-small cell lung cancer , 2016, Oncotarget.
[4] Longyun Li,et al. Downregulation of microRNA-218 relieves neuropathic pain by regulating suppressor of cytokine signaling 3. , 2016, International journal of molecular medicine.
[5] A. Jemal,et al. Cancer statistics in China, 2015 , 2016, CA: a cancer journal for clinicians.
[6] J Carl Barrett,et al. EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291. , 2015, Lung cancer.
[7] C. Croce,et al. MicroRNA-224 promotes tumor progression in nonsmall cell lung cancer , 2015, Proceedings of the National Academy of Sciences.
[8] A. Jemal,et al. Global cancer statistics, 2012 , 2015, CA: a cancer journal for clinicians.
[9] Xiaowei Wang,et al. miRDB: an online resource for microRNA target prediction and functional annotations , 2014, Nucleic Acids Res..
[10] S. Jang,et al. Epigenetic silencing of microRNA-373 to epithelial-mesenchymal transition in non-small cell lung cancer through IRAK2 and LAMP1 axes. , 2014, Cancer letters.
[11] S. Lawler,et al. MicroRNAs in cancer: biomarkers, functions and therapy. , 2014, Trends in molecular medicine.
[12] P. Verde,et al. miR-340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer , 2014, Oncogene.
[13] H. Saji,et al. A worldwide trend of increasing primary adenocarcinoma of the lung , 2014, Surgery Today.
[14] T. Ochiya,et al. The role of microRNAs in the regulation of cancer stem cells , 2014, Front. Genet..
[15] Hui Zhou,et al. starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data , 2013, Nucleic Acids Res..
[16] J. Xiong,et al. Downregulation of miR‐16 promotes growth and motility by targeting HDGF in non‐small cell lung cancer cells , 2013, FEBS letters.
[17] Jianming Chen,et al. MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity. , 2013, Neuro-oncology.
[18] F. Slack,et al. miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. , 2012, Cancer research.
[19] Jiyun Yang,et al. MicroRNA-126 Inhibits Tumor Cell Growth and Its Expression Level Correlates with Poor Survival in Non-Small Cell Lung Cancer Patients , 2012, PloS one.
[20] E. Wang,et al. SOCS3 expression is inversely correlated with Pyk2 in non-small cell lung cancer and exogenous SOCS3 inhibits proliferation and invasion of A549 cells , 2012, Pathology.
[21] J. Visvader,et al. Aldehyde Dehydrogenase Activity Is a Biomarker of Primitive Normal Human Mammary Luminal Cells , 2012, Stem cells.
[22] Kazuya Kawahara,et al. miR-218 on the genomic loss region of chromosome 4p15.31 functions as a tumor suppressor in bladder cancer. , 2011, International journal of oncology.
[23] Jiayuh Lin,et al. LLL12 inhibits endogenous and exogenous interleukin-6-induced STAT3 phosphorylation in human pancreatic cancer cells. , 2011, Anticancer research.
[24] Z. Bacso,et al. miR‐126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5 , 2011, FEBS letters.
[25] S. Chiou,et al. Chemoresistance of lung cancer stemlike cells depends on activation of Hsp27 , 2011, Cancer.
[26] Cheng-Ta Yang,et al. Adenovirus-mediated SOCS3 gene transfer inhibits the growth and enhances the radiosensitivity of human non-small cell lung cancer cells. , 2010, Oncology reports.
[27] Huazong Zeng,et al. miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc , 2010, Journal of experimental & clinical cancer research : CR.
[28] Hui Zhou,et al. starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data , 2010, Nucleic Acids Res..
[29] E. Olson,et al. Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. , 2010, Cancer cell.
[30] Belinda E. Clarke,et al. MicroRNA-218 Is Deleted and Downregulated in Lung Squamous Cell Carcinoma , 2010, PloS one.
[31] Alexander Pertsemlidis,et al. MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs , 2010, Journal of experimental & clinical cancer research : CR.
[32] E. Dmitrovsky,et al. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors. , 2010, The Journal of clinical investigation.
[33] D. Fan,et al. MiR-218 Inhibits Invasion and Metastasis of Gastric Cancer by Targeting the Robo1 Receptor , 2010, PLoS genetics.
[34] Hansjuerg Alder,et al. miR-221&222 regulate TRAIL resistance and enhance tumorigenicity through PTEN and TIMP3 downregulation. , 2009, Cancer cell.
[35] C. Croce,et al. MicroRNAs in Cancer. , 2009, Annual review of medicine.
[36] F. Monzon,et al. Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells , 2008, Oncogene.
[37] Phillip A Sharp,et al. Suppression of non-small cell lung tumor development by the let-7 microRNA family , 2008, Proceedings of the National Academy of Sciences.
[38] Michael Kertesz,et al. The role of site accessibility in microRNA target recognition , 2007, Nature Genetics.
[39] T Takahashi,et al. Apoptosis induction by antisense oligonucleotides against miR-17-5p and miR-20a in lung cancers overexpressing miR-17-92 , 2007, Oncogene.
[40] C. Croce,et al. MicroRNA signatures in human cancers , 2006, Nature Reviews Cancer.
[41] Xinmin Cao,et al. Structure, function, and regulation of STAT proteins. , 2006, Molecular bioSystems.
[42] M. Meyerson,et al. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. , 2006, Cancer research.
[43] Stijn van Dongen,et al. miRBase: microRNA sequences, targets and gene nomenclature , 2005, Nucleic Acids Res..
[44] Y. Yatabe,et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. , 2005, Cancer research.
[45] K. Gunsalus,et al. Combinatorial microRNA target predictions , 2005, Nature Genetics.
[46] C. Burge,et al. Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.
[47] V. Ambros. The functions of animal microRNAs , 2004, Nature.
[48] Y. Yatabe,et al. Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival , 2004, Cancer Research.
[49] A. Jemal,et al. Cancer statistics, 2015 , 2015, CA: a cancer journal for clinicians.
[50] N. Sabri,et al. Role of STAT3 in lung cancer. , 2014, JAK-STAT.
[51] J. Shih,et al. ALDH-positive lung cancer stem cells confer resistance to epidermal growth factor receptor tyrosine kinase inhibitors. , 2013, Cancer letters.
[52] Wei Wu. MicroRNA and Cancer , 2011, Methods in Molecular Biology.
[53] A. Jemal,et al. Global Cancer Statistics , 2011 .
[54] Li Lin,et al. A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells. , 2010, Neoplasia.
[55] A. Jemal,et al. Global cancer statistics , 2011, CA: a cancer journal for clinicians.
[56] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.