Magnetic Resonance Spectroscopy Diagnosis of Neurological Diseases

Introduction MRS basic physics of MR the clinical significance of metabolites an introduction to clinical cases clinical cases degenerative disease - Alzheimer disease, dementia, Huntington's disease, Parkinson's disease systemic diseases - liver disease, diabetes mellitus osmolar abnormalities trauma - SIADH, hyper-osmolar state, diffuse axonal injury, hypoxic injury global hypoxia -vascular diseases, stroke, infarcts and non vascular focal hypoxia focal lesions - ectopic grey matter, HIV related lesions, tumours and tuberculoma multiple sclerosis and other inflammatory disease paediatrics - abnormal development, Reyes syndrome, inborn errors of metabolism xenobiotics - ethanol, propylene, glycol, mannitol MRS patterns and referral guidelines.