Signal transduction and actin filament organization.

[1]  S. Zigmond,et al.  Actin filament barbed-end capping activity in neutrophil lysates: the role of capping protein-beta 2. , 1995, Molecular biology of the cell.

[2]  S. Zigmond,et al.  Actin Polymerization Induced by GTPγS in Permeabilized Neutrophils Is Induced and Maintained by Free Barbed Ends (*) , 1995, The Journal of Biological Chemistry.

[3]  J. Benovic,et al.  The β-Adrenergic Receptor Kinase (GRK2) Is Regulated by Phospholipids (*) , 1995, The Journal of Biological Chemistry.

[4]  J. Oliver,et al.  Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by Fc epsilon R1 cross-linking. , 1995, Molecular biology of the cell.

[5]  J. Theriot,et al.  Asymmetric distribution of the Listeria monocytogenes ActA protein is required and sufficient to direct actin‐based motility , 1995, Molecular microbiology.

[6]  Jonathan A. Cooper,et al.  Rho family members: Activators of MAP kinase cascades , 1995, Cell.

[7]  P. Janmey,et al.  Thrombin receptor ligation and activated rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets , 1995, Cell.

[8]  T. Tanaka,et al.  Activation Induces Dephosphorylation of Cofilin and Its Translocation to Plasma Membranes in Neutrophil-like Differentiated HL-60 Cells (*) , 1995, The Journal of Biological Chemistry.

[9]  A. Bretscher,et al.  Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site. , 1995, Molecular biology of the cell.

[10]  L. Cantley,et al.  Rho Family GTPases Bind to Phosphoinositide Kinases (*) , 1995, The Journal of Biological Chemistry.

[11]  J. Bamburg,et al.  Reactivation of Phosphorylated Actin Depolymerizing Factor and Identification of the Regulatory Site (*) , 1995, The Journal of Biological Chemistry.

[12]  J. Parsons,et al.  Interaction of Focal Adhesion Kinase with Cytoskeletal Protein Talin (*) , 1995, The Journal of Biological Chemistry.

[13]  G. Bokoch,et al.  Regulation of human leukocyte p21-activated kinases through G protein--coupled receptors. , 1995, Science.

[14]  S. Haskill,et al.  Integrin-mediated Tyrosine Phosphorylation and Cytokine Message Induction in Monocytic Cells , 1995, The Journal of Biological Chemistry.

[15]  Sheila M. Thomas,et al.  Specific and redundant roles of Src and Fyn in organizing the cytoskeleton , 1995, Nature.

[16]  M. Karin,et al.  Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs , 1995, Cell.

[17]  P. Crespo,et al.  The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway , 1995, Cell.

[18]  F. McCormick,et al.  Rac mediates growth factor-induced arachidonic acid release , 1995, Cell.

[19]  L. Brass,et al.  Pleckstrin Inhibits Phosphoinositide Hydrolysis Initiated by G-protein-coupled and Growth Factor Receptors. A ROLE FOR PLECKSTRIN'S PH DOMAINS (*) , 1995, The Journal of Biological Chemistry.

[20]  W. Moolenaar,et al.  Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger (*) , 1995, The Journal of Biological Chemistry.

[21]  John G. Collard,et al.  A role for Rac in Tiaml-induced membrane ruffling and invasion , 1995, Nature.

[22]  E. Prigmore,et al.  A 68-kDa Kinase and NADPH Oxidase Component p67 Are Targets for Cdc42Hs and Rac1 in Neutrophils (*) , 1995, The Journal of Biological Chemistry.

[23]  S. Abramson,et al.  Translocation of p21rac2 from cytosol to plasma membrane is neither necessary nor sufficient for neutrophil NADPH oxidase activity , 1995, The Journal of Biological Chemistry.

[24]  J. Ding,et al.  Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils , 1995, The Journal of Biological Chemistry.

[25]  A. Toker,et al.  Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation , 1995, The Journal of Biological Chemistry.

[26]  M. Olson,et al.  Direct Involvement of the Small GTP-binding Protein Rho in lbc Oncogene Function (*) , 1995, The Journal of Biological Chemistry.

[27]  K. Titani,et al.  Identification of Two 17-kDa Rat Parotid Gland Phosphoproteins, Subjects for Dephosphorylation upon β-Adrenergic Stimulation, as Destrin- and Cofilin-like Proteins (*) , 1995, The Journal of Biological Chemistry.

[28]  C. Nobes,et al.  Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia , 1995, Cell.

[29]  P. Hawkins,et al.  PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase , 1995, Current Biology.

[30]  L. Lim,et al.  The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts , 1995, Molecular and cellular biology.

[31]  U. Walter,et al.  The proline‐rich focal adhesion and microfilament protein VASP is a ligand for profilins. , 1995, The EMBO journal.

[32]  U. Walter,et al.  A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin‐based cytoskeleton of mammalian cells. , 1995, The EMBO journal.

[33]  F. McCormick,et al.  An essential role for Rac in Ras transformation , 1995, Nature.

[34]  I. Gout,et al.  Sequestration of a G-protein βγ Subunit or ADP-ribosylation of Rho Can Inhibit Thrombin-induced Activation of Platelet Phosphoinositide 3-Kinases (*) , 1995, The Journal of Biological Chemistry.

[35]  V. Kaartinen,et al.  Increased neutrophil respiratory burst in bcr-null mutants , 1995, Cell.

[36]  P. Mangeat,et al.  Ezrin NH2-terminal domain inhibits the cell extension activity of the COOH-terminal domain , 1995, The Journal of cell biology.

[37]  K. Pestonjamasp,et al.  Moesin, ezrin, and p205 are actin-binding proteins associated with neutrophil plasma membranes. , 1995, Molecular biology of the cell.

[38]  E. Prossnitz,et al.  Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase. , 1995, Journal of immunology.

[39]  I. Boronenkov,et al.  The Sequence of Phosphatidylinositol-4-phosphate 5-Kinase Defines a Novel Family of Lipid Kinases (*) , 1995, The Journal of Biological Chemistry.

[40]  Tony Pawson,et al.  Protein modules and signalling networks , 1995, Nature.

[41]  Kenneth M. Yamada,et al.  Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function , 1995, Science.

[42]  D. Drubin,et al.  Regulation of cortical actin cytoskeleton assembly during polarized cell growth in budding yeast , 1995, The Journal of cell biology.

[43]  A. Hall,et al.  A novel type of myosin implicated in signalling by rho family GTPases. , 1995, EMBO Journal.

[44]  P. Comoglio,et al.  Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells , 1995, Molecular and cellular biology.

[45]  S. Craig,et al.  F-actin binding site masked by the intramolecular association of vinculin head and tail domains , 1995, Nature.

[46]  G M Bokoch,et al.  Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. , 1994, The Journal of biological chemistry.

[47]  A. Hall,et al.  GAPs for rho-related GTPases. , 1994, Trends in genetics : TIG.

[48]  R. Herrera,et al.  Expression of α1‐chimaerin (rac‐1 GAP) alters the cytoskeletal and adhesive properties of fibroblasts , 1994, Journal of cellular biochemistry.

[49]  L. Cantley,et al.  Cloning and characterization of a human phosphatidylinositol 4-kinase. , 1994, The Journal of biological chemistry.

[50]  S. Narumiya,et al.  Botulinum C3 exoenzyme blocks the tyrosine phosphorylation of p125FAK and paxillin induced by bombesin and endothelin , 1994, FEBS letters.

[51]  R. Kahn,et al.  Effects of acid phospholipids on nucleotide exchange properties of ADP-ribosylation factor 1. Evidence for specific interaction with phosphatidylinositol 4,5-bisphosphate. , 1994, The Journal of biological chemistry.

[52]  L. Chong,et al.  The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells , 1994, Cell.

[53]  Louis E Reichardt,et al.  Vinculin-deficient PC12 cell lines extend unstable lamellipodia and filopodia and have a reduced rate of neurite outgrowth , 1994, The Journal of cell biology.

[54]  K. Sada,et al.  Involvement of protein-tyrosine kinase p72syk in collagen-induced signal transduction in platelets. , 1994, European journal of biochemistry.

[55]  M. Kinch,et al.  Integrin-mediated cell adhesion activates mitogen-activated protein kinases. , 1994, The Journal of biological chemistry.

[56]  J. Brugge,et al.  Adhesive signaling in platelets. , 1994, Current opinion in cell biology.

[57]  David Hang.  Refusing the ovarian time bomb: three viewpoints and a reply , 1994 .

[58]  P. Hajduk,et al.  Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate , 1994, Nature.

[59]  A. Vaheri,et al.  Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein family , 1994, The Journal of cell biology.

[60]  R. Haslam,et al.  Dephosphorylation of cofilin in stimulated platelets: roles for a GTP-binding protein and Ca2+. , 1994, The Biochemical journal.

[61]  N. Sato,et al.  Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family members , 1994, The Journal of cell biology.

[62]  D. Kandzari,et al.  Growth factor receptors, phospholipases, phospholipid kinases and actin reorganization. , 1994, Seminars in cell biology.

[63]  P. Janmey,et al.  Interactions of tensin with actin and identification of its three distinct actin-binding domains , 1994, The Journal of cell biology.

[64]  A. Ridley,et al.  Signal transduction pathways regulating Rho‐mediated stress fibre formation: requirement for a tyrosine kinase. , 1994, The EMBO journal.

[65]  John G. Collard,et al.  Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins , 1994, Cell.

[66]  A. Ridley.  Membrane ruffling and signal transduction , 1994, BioEssays : news and reviews in molecular, cellular and developmental biology.

[67]  T. Sasaki,et al.  rac p21 is involved in insulin-induced membrane ruffling and rho p21 is involved in hepatocyte growth factor- and 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced membrane ruffling in KB cells , 1994, Molecular and cellular biology.

[68]  J. Apgar.  Polymerization of actin in RBL-2H3 cells can be triggered through either the IgE receptor or the adenosine receptor but different signaling pathways are used. , 1994, Molecular biology of the cell.

[69]  C. Nobes,et al.  Regulation and function of the Rho subfamily of small GTPases. , 1994, Current opinion in genetics & development.

[70]  C. Heldin,et al.  Membrane ruffling and chemotaxis transduced by the PDGF beta-receptor require the binding site for phosphatidylinositol 3' kinase. , 1994, Oncogene.

[71]  L. Lim,et al.  A brain serine/threonine protein kinase activated by Cdc42 and Rac1 , 1994, Nature.

[72]  Marie-France Carlier,et al.  How profilin promotes actin filament assembly in the presence of thymosin β4 , 1993, Cell.

[73]  C. Marshall,et al.  rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo. , 1993, The EMBO journal.

[74]  S. Falkow,et al.  Salmonella typhimurium induces membrane ruffling by a growth factor-receptor-independent mechanism. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[75]  L. Tertoolen,et al.  Epidermal growth factor—induced actin remodeling is regulated by 5-lipoxygenase and cyclooxygenase products , 1993, Cell.

[76]  T. E. Morgan,et al.  Isolation and characterization of a regulated form of actin depolymerizing factor , 1993, The Journal of cell biology.

[77]  M. Schwartz,et al.  Adhesion to fibronectin stimulates inositol lipid synthesis and enhances PDGF-induced inositol lipid breakdown , 1993, The Journal of cell biology.

[78]  A. Hall,et al.  Signal transduction through small GTPases—A tale of two GAPs , 1992, Cell.

[79]  S. Zigmond,et al.  Chemoattractant-stimulated polymorphonuclear leukocytes contain two populations of actin filaments that differ in their spatial distributions and relative stabilities , 1990, The Journal of cell biology.

[80]  S. Tsukita,et al.  A new 82-kD barbed end-capping protein (radixin) localized in the cell- to-cell adherens junction: purification and characterization , 1989, The Journal of cell biology.

[81]  A. Bretscher.  Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factor , 1989, The Journal of cell biology.

[82]  M. Schwartz,et al.  How actin binds and assembles onto plasma membranes from Dictyostelium discoideum , 1988, The Journal of cell biology.

[83]  Hui-qiao Sun,et al.  Actin monomer binding proteins. , 1995, Current opinion in cell biology.

[84]  M. Symons.  The Rac and Rho pathways as a source of drug targets for Ras-mediated malignancies. , 1995, Current opinion in biotechnology.

[85]  P. Hawkins,et al.  Activation of the small GTP-binding proteins rho and rac by growth factor receptors. , 1995, Journal of cell science.

[86]  D. McClay,et al.  Characterization of moesin in the sea urchin Lytechinus variegatus: redistribution to the plasma membrane following fertilization is inhibited by cytochalasin B. , 1995, Journal of cell science.

[87]  J. Apgar,et al.  Activation of protein kinase C in rat basophilic leukemia cells stimulates increased production of phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate: correlation with actin polymerization. , 1995, Molecular biology of the cell.

[88]  P. Janmey,et al.  Phosphoinositides and calcium as regulators of cellular actin assembly and disassembly. , 1994, Annual review of physiology.

[89]  A. Hall,et al.  Small GTP-binding proteins and the regulation of the actin cytoskeleton. , 1994, Annual review of cell biology.