An improved automated method for the measurement of thermal thresholds. 1. Normal subjects.

Clinical tests of thermal sensation are poorly quantified and not strictly modality specific. Previous automated thermal testing systems have had limited usefulness with high intra-and inter-individual variability. This paper describes an automated thermal system (Glasgow system) which is an extensive modification of previous techniques to answer these criticisms. It comprises a microprocessor-driven Peltier element and utilises the forced choice method of psychophysical analysis to determine the thresholds to thermal stimulation. In a control group of 106 healthy subjects the mean heat threshold for the wrist was found to be 0.23 degree C (SD = 0.06 degree C) and the mean cold threshold 0.15 degree C (SD = 0.05 degree C). Repeated determinations showed a maximum of 5% intra-individual variation in comparison to previously reported values of up to 150%.

[1]  P. P. Lele,et al.  Relationship between cutaneous thermal thresholds, skin temperature and cross‐sectional area of the stimulus , 1954, The Journal of physiology.

[2]  P. P. Lele,et al.  The relationship between heat transfer, skin temperature and cutaneous sensibility , 1954, The Journal of physiology.

[3]  E. Hendler,et al.  Infrared and microwave effects on skin heating and temperature sensation. , 1960, IRE transactions on medical electronics.

[4]  D. Kenshalo.  Improved method for the psychophysical study of the temperature sense , 1963 .

[5]  G. B. Wetherill,et al.  Sequential estimation of quantal response curves: A new method of estimation , 1966 .

[6]  D. Kenshalo,et al.  Temporal Course of Thermal Adaptation , 1966, Science.

[7]  H. F. Poppendiek,et al.  Thermal conductivity measurements and predictions for biological fluids and tissues , 1967 .

[8]  D. Kenshalo,et al.  Warm and cool thresholds as a function of rate of stimulus temperature change , 1968 .

[9]  D. Kenshalo,et al.  Psychophysical studies of temperature sensitivity. , 1970, Contributions to sensory physiology.

[10]  R. Sekuler,et al.  Sensitive, objective procedure for evaluating response to light touch , 1973, Neurology.

[11]  L E Marks,et al.  Regional sensitivity and spatial summation in the warmth sense. , 1974, Physiology & behavior.

[12]  I. Darian‐Smith,et al.  A contact stimulator for the study of cutaneous thermal sensibility. , 1974, Journal of applied physiology.

[13]  K. Offord,et al.  Description of “Minnesota Thermal Disks” and normal values of cutaneous thermal discrimination in man , 1974, Neurology.

[14]  D. Kenshalo,et al.  A device to measure cutaneous temperature sensitivity in humans and subhuman species. , 1975, Journal of applied physiology.

[15]  P. Hazemann,et al.  Handbook of Electroencephalography and Clinical Neurophysiology , 1975 .

[16]  H. Fruhstorfer,et al.  Method for quantitative estimation of thermal thresholds in patients. , 1976, Journal of neurology, neurosurgery, and psychiatry.

[17]  J D Greenspan,et al.  The effects of rate of temperature change and adapting temperature on thermal sensitivity. , 1977, Sensory processes.

[18]  R. Duclaux.  [Cutaneous thermoreceptors]. , 1977, Journal de physiologie.

[19]  M. L. Cohen,et al.  Measurement of the thermal properties of human skin. A review. , 1977, The Journal of investigative dermatology.

[20]  Thermal properties of human skin related to nondestructive measurement of epidermal thickness. , 1977, The Journal of investigative dermatology.

[21]  P. Dyck,et al.  Introduction of automated systems to evaluate touch‐pressure, vibration, and thermal cutaneous sensation in man , 1978, Annals of neurology.

[22]  R T Verrillo,et al.  Sensory functions in chronic neuralgia. , 1979, Journal of neurology, neurosurgery, and psychiatry.

[23]  D. Kenshalo.  Sensory Functions of the Skin of Humans , 2011, Springer US.

[24]  A. Vallbo,et al.  Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. , 1979, Physiological reviews.

[25]  H. Hensel,et al.  The Neural Basis of the Sensory Quality of Warmth , 1979 .

[26]  L. Wahren,et al.  Variability of sensory threshold determination in clinical use , 1981, Journal of the Neurological Sciences.

[27]  D. Ottoson,et al.  Somatosensory Mechanisms , 1984, Wenner-Gren Center International Symposium Series.