Sodium-hydrogen exchange inhibition attenuates in vivo porcine myocardial stunning.

[1]  A. Pries,et al.  Cariporide (HOE 642) Attenuates Leukocyte Activation in Ischemia and Reperfusion , 2001, Anesthesia and analgesia.

[2]  S. Schaefer,et al.  Na(+)/H(+) exchange subtype 1 inhibition reduces endothelial dysfunction in vessels from stunned myocardium. , 2001, American journal of physiology. Heart and circulatory physiology.

[3]  R. Gazmuri,et al.  Successful Ventricular Defibrillation by the Selective Sodium-Hydrogen Exchanger Isoform-1 Inhibitor Cariporide , 2001, Circulation.

[4]  F. Rega,et al.  Na(+)/H(+)-exchange inhibition and aprotinin administration: promising tools for myocardial protection during minimally invasive CABG. , 2001, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[5]  R. Mentzer,et al.  Beneficial effects of adenosine A(2a) agonist CGS-21680 in infarcted and stunned porcine myocardium. , 2001, American journal of physiology. Heart and circulatory physiology.

[6]  Yongge Liu,et al.  Mitochondrial ATP-sensitive K+ channels play a role in cardioprotection by Na+-H+ exchange inhibition against ischemia/reperfusion injury. , 2001, Journal of the American College of Cardiology.

[7]  A. Busch,et al.  NHE1-inhibitor cariporide prevents the transient reperfusion-induced shortening of the monophasic action potential after coronary ischemia in pigs , 2001, Basic Research in Cardiology.

[8]  H. White,et al.  Inhibition of the Sodium-Hydrogen Exchanger With Cariporide to Prevent Myocardial Infarction in High-Risk Ischemic Situations: Main Results of the GUARDIAN Trial , 2000, Circulation.

[9]  D. Allen,et al.  Activity of the Na(+)/H(+) exchanger is critical to reperfusion damage and preconditioning in the isolated rat heart. , 2000, Cardiovascular research.

[10]  R. Bohle,et al.  Na+/H+ Exchange Inhibitor Cariporide Attenuates Cell Injury Predominantly During Ischemia and Not at Onset of Reperfusion in Porcine Hearts With Low Residual Blood Flow , 2000, Circulation.

[11]  G. Gross,et al.  Na(+)/H(+) exchange inhibition-induced cardioprotection in dogs: effects on neutrophils versus cardiomyocytes. , 2000, American journal of physiology. Heart and circulatory physiology.

[12]  S. Harding,et al.  Sarcolemmal Na+/H+ exchanger activity and expression in human ventricular myocardium. , 2000, Journal of the American College of Cardiology.

[13]  S. Neubauer,et al.  Na(+)/H(+) exchange inhibition with HOE642 improves postischemic recovery due to attenuation of Ca(2+) overload and prolonged acidosis on reperfusion. , 2000, Circulation.

[14]  H. Otani,et al.  Effects Of The Na+/H+ Exchange Inhibitor Cariporide (HOE 642) On Cardiac Function And Cardiomyocyte Cell Death In Rat Ischaemic–Reperfused Heart , 2000, Clinical and experimental pharmacology & physiology.

[15]  J. Soler‐Soler,et al.  Protective Effect of HOE642, a Selective Blocker of Na+‐H+ Exchange, Against the Development of Rigor Contracture in Rat Ventricular Myocytes , 2000, Experimental physiology.

[16]  U. Decking,et al.  Blocking Na(+)-H+ exchange by cariporide reduces Na(+)-overload in ischemia and is cardioprotective. , 1999, Journal of molecular and cellular cardiology.

[17]  B. Eigel,et al.  Contribution of the Na+channel and Na+/H+exchanger to the anoxic rise of [Na+] in ventricular myocytes. , 1999, American journal of physiology. Heart and circulatory physiology.

[18]  M. Blaustein,et al.  Sodium/calcium exchange: its physiological implications. , 1999, Physiological reviews.

[19]  M. Karmazyn.  The Role of the Myocardial Sodium‐Hydrogen Exchanger in Mediating Ischemic and Reperfusion Injury: From Amiloride to Cariporide a , 1999, Annals of the New York Academy of Sciences.

[20]  Y. Ladilov,et al.  Cardioprotective effects of KB-R7943: a novel inhibitor of the reverse mode of Na+/Ca2+exchanger. , 1999, American journal of physiology. Heart and circulatory physiology.

[21]  R. Vaughan-Jones,et al.  Characterization of intracellular pH regulation in the guinea‐pig ventricular myocyte , 1999, The Journal of physiology.

[22]  R. Mentzer,et al.  Ischemic preconditioning does not acutely improve load-insensitive parameters of contractility in in vivo stunned porcine myocardium. , 1999, The Journal of thoracic and cardiovascular surgery.

[23]  S. Schaefer,et al.  Na-H exchange inhibition with cariporide limits functional impairment caused by repetitive ischemia. , 1998, Journal of cardiovascular pharmacology.

[24]  B. Ghaleh,et al.  Lack of effects of the Na+/H+ exchanger inhibitor, cariporide against myocardial stunning in exercise‐induced ischemia in dogs , 1998, Fundamental & clinical pharmacology.

[25]  W. Linz,et al.  Dose-dependent reduction of myocardial infarct mass in rabbits by the NHE-1 inhibitor cariporide (HOE 642). , 1998, Clinical and experimental hypertension.

[26]  C. Schade-Brittinger,et al.  Time-dependent protection by Na+/H+ exchange inhibition in a regionally ischemic, reperfused porcine heart preparation with low residual blood flow. , 1998, Journal of molecular and cellular cardiology.

[27]  M. Galiñanes,et al.  Na+/H+ exchanger inhibitor HOE-642 improves cardioplegic myocardial preservation under both normothermic and hypothermic conditions. , 1997, Circulation.

[28]  R. Bohle,et al.  Time delay of cell death by Na+/H+-exchange inhibition in regionally ischemic, reperfused porcine hearts. , 1997, Journal of cardiovascular pharmacology.

[29]  R. Vaughan-Jones,et al.  Interaction between Na+ and H+ ions on Na-H exchange in sheep cardiac Purkinje fibers. , 1997, Journal of molecular and cellular cardiology.

[30]  M. Karmazyn,et al.  Effect of sodium-hydrogen exchange inhibition on functional and metabolic impairment produced by oxidative stress in the isolated rat heart. , 1997, Canadian journal of physiology and pharmacology.

[31]  H. Lang,et al.  Effects of the Na+/H+-exchange inhibitor Hoe 642 on intracellular pH, calcium and sodium in isolated rat ventricular myocytes , 1996, Pflügers Archiv.

[32]  T. Ehring,et al.  Stunned myocardium and the attenuation of stunning by calcium antagonists. , 1995, The American journal of cardiology.

[33]  W. Linz,et al.  Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion. , 1995, Cardiovascular research.

[34]  R. Bolli.  Role of neutrophils in myocardial stunning after brief ischaemia: the end of a six year old controversy (1987-1993) , 1993, Cardiovascular research.

[35]  D. Nicoll,et al.  Sodium-calcium exchange. , 1992, Current opinion in cell biology.

[36]  D. Glower,et al.  Quantification of regional myocardial dysfunction after acute ischemic injury. , 1988, The American journal of physiology.

[37]  A. Tauber,et al.  Proton secretion by the sodium/hydrogen ion antiporter in the human neutrophil. , 1986, The Journal of clinical investigation.