Focus Issue: Signaling Across Membranes

This week’s issues of Science and Science’s STKE focus on movement of molecules and information across cellular membranes. Science highlights the mechanisms by which proteins, ions, and DNA cross the membranes of eukaryotic and prokaryotic cells. STKE addresses how information is transmitted across cell membranes to allow cells to communicate with each other and to respond to signals in their environments.

[1]  R. MacKinnon,et al.  Principles of Selective Ion Transport in Channels and Pumps , 2005, Science.

[2]  K. Mikoshiba,et al.  Novel Compartment Implicated in Calcium Signaling—Is It an "Induced Coupling Domain"? , 2005, Science's STKE.

[3]  W. Catterall,et al.  The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis , 2004, Science's STKE.

[4]  Jie Zheng,et al.  Patch-Clamp Fluorometry Recording of Conformational Rearrangements of Ion Channels , 2003, Science's STKE.

[5]  E. M. Adler,et al.  Focus Issue: Tuning in to the Ion Channel , 2004, Science's STKE.

[6]  R. Vandenberg,et al.  How and Why Are Channels in Transporters? , 2005, Science's STKE.

[7]  R. Schwinger,et al.  Calcium and the Failing Heart: Phospholamban, Good Guy or Bad Guy? , 2003, Science's STKE.

[8]  M. Diversé-Pierluissi.  Regulation of Ion Channels by G Proteins , 2005, Science's STKE.

[9]  J. Tam,et al.  Dissecting Intracellular Signaling Pathways with Membrane-Permeable Peptides , 2000, Science's STKE.

[10]  J. Groves.  Learning the Chemical Language of Cell-Surface Interactions , 2005, Science's STKE.

[11]  D. Felsenfeld,et al.  Regulation of Complexes by Cytoskeletal Elements: Integrins Serve as Force Transducers Linking Mechanical Stimuli and Biochemical Signals , 2005, Science's STKE.

[12]  A. Joliot.  Transduction Peptides Within Naturally Occurring Proteins , 2005, Science's STKE.

[13]  M. Purbhoo,et al.  Long-Distance Calls Between Cells Connected by Tunneling Nanotubules , 2005, Science's STKE.