B-Cell Depletion Reduces the Maturation of Cerebral Cavernous Malformations in Murine Models
暂无分享,去创建一个
R. Shenkar | I. Awad | A. Louvi | M. Gunel | Ying Cao | D. Marchuk | R. Girard | H. Zeineddine | M. Fam | Changbin Shi | Thomas Moore | R. Lightle | C. Gallione | C. Austin | Lingjiao Zhang | A. Rorrer | Meijing Wu
[1] R. Shenkar,et al. Vascular Permeability in Cerebral Cavernous Malformations , 2015, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[2] W. Min,et al. EXCEPTIONAL AGGRESSIVENESS OF CEREBRAL CAVERNOUS MALFORMATION DISEASE ASSOCIATED WITH PDCD10 MUTATIONS , 2014, Genetics in Medicine.
[3] C. McCulloch,et al. Polymorphisms in Inflammatory and Immune Response Genes Associated with Cerebral Cavernous Malformation Type 1 Severity , 2014, Cerebrovascular Diseases.
[4] C. Abreu-Goodger,et al. The miR-155–PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation , 2014, The Journal of experimental medicine.
[5] K. Frei,et al. Bleeding propensity of cavernous malformations: impact of tight junction alterations on the occurrence of overt hematoma. , 2014, Journal of neurosurgery.
[6] R. Shenkar,et al. Immune complex formation and in situ B-cell clonal expansion in human cerebral cavernous malformations , 2014, Journal of Neuroimmunology.
[7] Jon Thacker,et al. Evaluation of Iron Content in Human Cerebral Cavernous Malformation Using Quantitative Susceptibility Mapping , 2014, Investigative radiology.
[8] G. Johnson,et al. Cerebral cavernous malformation is a vascular disease associated with activated RhoA signaling , 2013, Biological chemistry.
[9] C. Scully,et al. Biologics in oral medicine: ulcerative disorders. , 2013, Oral diseases.
[10] S. Lazic,et al. A call for transparent reporting to optimize the predictive value of preclinical research , 2012, Nature.
[11] F. Deisenhammer,et al. Alemtuzumab more effective than interferon β-1a at 5-year follow-up of CAMMS223 clinical trial , 2012, Neurology.
[12] H. Sullivan,et al. Alemtuzumab more effective than interferon β-1a at 5-year follow-up of CAMMS223 Clinical Trial , 2012, Neurology.
[13] C. Warlow,et al. Untreated clinical course of cerebral cavernous malformations: a prospective, population-based cohort study , 2012, The Lancet Neurology.
[14] R. Shenkar,et al. Fasudil Decreases Lesion Burden in a Murine Model of Cerebral Cavernous Malformation Disease , 2012, Stroke.
[15] B. Thompson,et al. Natural history and imaging prevalence of cavernous malformations in children and young adults. , 2012, Journal of neurosurgery. Pediatrics.
[16] W. Min,et al. Loss of cerebral cavernous malformation 3 (Ccm3) in neuroglia leads to CCM and vascular pathology , 2011, Proceedings of the National Academy of Sciences.
[17] R. Kucherlapati,et al. A novel mouse model of cerebral cavernous malformations based on the two-hit mutation hypothesis recapitulates the human disease. , 2011, Human molecular genetics.
[18] R. Shenkar,et al. Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity , 2010, The Journal of experimental medicine.
[19] E. Tournier-Lasserve,et al. Recent insights into cerebral cavernous malformations: the molecular genetics of CCM , 2010, The FEBS journal.
[20] N. Sciaky,et al. Rho Kinase Inhibition Rescues the Endothelial Cell Cerebral Cavernous Malformation Phenotype* , 2010, The Journal of Biological Chemistry.
[21] J. Singh,et al. Abatacept for Rheumatoid Arthritis: A Cochrane Systematic Review , 2010, The Journal of Rheumatology.
[22] M. Smyth,et al. Type I natural killer T cells suppress tumors caused by p53 loss in mice. , 2009, Blood.
[23] R. Shenkar,et al. Immune response in human cerebral cavernous malformations. , 2009, Stroke.
[24] G. Steinberg,et al. Biallelic somatic and germline mutations in cerebral cavernous malformations (CCMs): evidence for a two-hit mechanism of CCM pathogenesis. , 2009, Human molecular genetics.
[25] Christopher A. Jones,et al. The Cerebral Cavernous Malformation signaling pathway promotes vascular integrity via Rho GTPases , 2009, Nature Medicine.
[26] Min Chen,et al. Complement Activation Is Involved in Renal Damage in Human Antineutrophil Cytoplasmic Autoantibody Associated Pauci-Immune Vasculitis , 2009, Journal of Clinical Immunology.
[27] L. Morrison,et al. Hemorrhage From Cavernous Malformations of the Brain: Definition and Reporting Standards , 2008, Stroke.
[28] R. Shenkar,et al. Oligoclonal immune response in cerebral cavernous malformations. Laboratory investigation. , 2007, Journal of neurosurgery.
[29] D. Danilenko,et al. Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade. , 2007, Blood.
[30] R. Pope,et al. Drug Insight: abatacept for the treatment of rheumatoid arthritis , 2006, Nature Clinical Practice Rheumatology.
[31] A. Paetau,et al. Complement activation associates with saccular cerebral artery aneurysm wall degeneration and rupture. , 2006, Neurosurgery.
[32] S. Sa,et al. A soluble BAFF antagonist, BR3-Fc, decreases peripheral blood B cells and lymphoid tissue marginal zone and follicular B cells in cynomolgus monkeys. , 2006, The American journal of pathology.
[33] P. Ridker,et al. Anti-Inflammatory Effects of Statins: Clinical Evidence and Basic Mechanisms , 2005, Nature Reviews Drug Discovery.
[34] R. Gascoyne,et al. Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[35] J. Bluestone,et al. An Important Role of CD80/CD86-CTLA-4 Signaling during Photocarcinogenesis in Mice1 , 2005, The Journal of Immunology.
[36] Helmut Mack,et al. Rho kinase, a promising drug target for neurological disorders , 2005, Nature Reviews Drug Discovery.
[37] D. Louis,et al. Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations. , 2004, The American journal of pathology.
[38] P. Schneider,et al. BAFF AND APRIL: a tutorial on B cell survival. , 2003, Annual review of immunology.
[39] R. Vile. Faculty Opinions recommendation of IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. , 2001 .
[40] R. Schreiber,et al. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity , 2001, Nature.
[41] J. Trapani,et al. Perforin-Mediated Cytotoxicity Is Critical for Surveillance of Spontaneous Lymphoma , 2000, The Journal of experimental medicine.
[42] I. Awad,et al. Ultrastructural pathological features of cerebrovascular malformations: a preliminary report. , 2000, Neurosurgery.
[43] R. Clatterbuck,et al. The natural history of cavernous malformations. , 1999, Neurosurgery clinics of North America.
[44] R. Schreiber,et al. Demonstration of an interferon γ-dependent tumor surveillance system in immunocompetent mice , 1998 .
[45] R. Schreiber,et al. Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[46] D. Kondziolka,et al. The natural history of cerebral cavernous malformations. , 1995, Journal of neurosurgery.
[47] I. Awad,et al. Intracranial cavernous malformations: lesion behavior and management strategies. , 1995, Neurosurgery.
[48] R F Spetzler,et al. The natural history of familial cavernous malformations: results of an ongoing study. , 1994, Journal of neurosurgery.
[49] John R. Robinson,et al. Pathological heterogeneity of angiographically occult vascular malformations of the brain. , 1993, Neurosurgery.
[50] H. Steiger,et al. Clinicopathological relations of cerebral cavernous angiomas: observations in eleven cases. , 1987, Neurosurgery.
[51] M. Hadley,et al. The MRI appearance of cavernous malformations (angiomas). , 1987, Journal of neurosurgery.