pathogenesispathophysiology: current concepts of
暂无分享,去创建一个
[1] James G Krueger,et al. Potential Role of the Chemokine Receptors CXCR3, CCR4, and the Integrin αEβ7 in the Pathogenesis of Psoriasis Vulgaris , 2001, Laboratory Investigation.
[2] M. Dhodapkar,et al. Increased Expression of Interleukin 23 p19 and p40 in Lesional Skin of Patients with Psoriasis Vulgaris , 2004, The Journal of experimental medicine.
[3] G. Hartmann,et al. Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases. , 2002, The Journal of investigative dermatology.
[4] P. Lenz,et al. IL-23 Production by Cosecretion of Endogenous p19 and Transgenic p40 in Keratin 14/p40 Transgenic Mice: Evidence for Enhanced Cutaneous Immunity , 2003, The Journal of Immunology.
[5] L. Kovarova,et al. Generation of antigen-loaded dendritic cells in a serum-free medium using different cytokine combinations. , 2003, Vaccine.
[6] H. Okamura,et al. IL-12 synergizes with IL-18 or IL-1β for IFN-γ production from human T cells , 2000 .
[7] R. Pine. Convergence of TNFα and IFNγ signalling pathways through synergistic induction of IRF-1/ISGF-2 is mediated by a composite GAS/κB promoter element , 1997 .
[8] Yong‐jun Liu,et al. Mouse and human dendritic cell subtypes , 2002, Nature Reviews Immunology.
[9] Jurg Ott,et al. A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis , 2003, Nature Genetics.
[10] T. Bieber,et al. Immunomorphological and ultrastructural characterization of Langerhans cells and a novel, inflammatory dendritic epidermal cell (IDEC) population in lesional skin of atopic eczema. , 1996, The Journal of investigative dermatology.
[11] D. Gladman,et al. CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis. , 2003, American journal of human genetics.
[12] S. Porcelli,et al. Overexpression of CD1d by Keratinocytes in Psoriasis and CD1d-Dependent IFN-γ Production by NK-T Cells1 , 2000, The Journal of Immunology.
[13] G. Yancopoulos,et al. Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. , 2003, Blood.
[14] M. Lebwohl,et al. A novel targeted T-cell modulator, efalizumab, for plaque psoriasis. , 2003, The New England journal of medicine.
[15] A. Menter,et al. Efalizumab for patients with moderate to severe plaque psoriasis: a randomized controlled trial. , 2003, JAMA.
[16] E. Weinman. New functions for the NHERF family of proteins. , 2001, The Journal of clinical investigation.
[17] U. Boehm,et al. Cellular responses to interferon-gamma. , 1997, Annual review of immunology.
[18] J. McGregor,et al. Epidermal dendritic cells in psoriasis possess a phenotype associated with antigen presentation: in situ expression of beta 2-integrins. , 1992, Journal of the American Academy of Dermatology.
[19] G. Krueger,et al. Development and use of alefacept to treat psoriasis. , 2003, Journal of the American Academy of Dermatology.
[20] C. Thompson,et al. Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets. , 1993, Journal of immunology.
[21] S. Shenolikar,et al. NHERF: targeting and trafficking membrane proteins. , 2001, American journal of physiology. Renal physiology.
[22] Yusuke Nakamura,et al. An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis , 2003, Nature Genetics.
[23] Albert Francis Blakeslee,et al. Department of Genetics , 1941 .
[24] M. Miyazaki,et al. Cutting Edge: Negative Regulation of Immune Synapse Formation by Anchoring Lipid Raft to Cytoskeleton Through Cbp-EBP50-ERM Assembly1 , 2002, The Journal of Immunology.
[25] A. Gottlieb,et al. Infliximab monotherapy provides rapid and sustained benefit for plaque-type psoriasis. , 2003, Journal of the American Academy of Dermatology.
[26] J. Kieffer,et al. Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells , 1997, Nature.
[27] T. Nomura,et al. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice , 2003, Nature.
[28] J Wagner,et al. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. , 2000, Immunity.
[29] R. Abraham,et al. Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3‐kinase inhibitors, wortmannin and LY294002. , 1996, The EMBO journal.
[30] J. Kieffer,et al. Inflammatory skin disease in K14/p40 transgenic mice: evidence for interleukin-12-like activities of p40. , 2001, The Journal of investigative dermatology.
[31] J. Krueger. The immunologic basis for the treatment of psoriasis with new biologic agents. , 2002, Journal of the American Academy of Dermatology.
[32] A. Bowcock,et al. The genetics of psoriasis, psoriatic arthritis and atopic dermatitis. , 2004, Human molecular genetics.
[33] L. Austin,et al. CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry. , 2000, Journal of autoimmunity.
[34] Wing Hung Wong,et al. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array. , 2003, Physiological genomics.
[35] Frank O. Nestle,et al. Spontaneous Development of Psoriasis in a New Animal Model Shows an Essential Role for Resident T Cells and Tumor Necrosis Factor-α , 2004, The Journal of experimental medicine.
[36] K. Urabe,et al. In situ Localization of CD83-Positive Dendritic Cells in Psoriatic Lesions , 2002, Dermatology.
[37] A. Bowcock,et al. Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q. , 1994, Science.
[38] F. Nestle,et al. Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines. , 1994, The Journal of clinical investigation.
[39] A. Gottlieb,et al. Etanercept as monotherapy in patients with psoriasis. , 2003, The New England journal of medicine.
[40] D. Gudbjartsson,et al. A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting. , 2003, American journal of human genetics.
[41] H. Tagami,et al. Comparison of the distribution and numbers of antigen-presenting cells among T-lymphocyte-mediated dermatoses , 2002, Archives of Dermatological Research.
[42] A. Roses,et al. Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map. , 2002, Genomics.
[43] Jens Holmberg,et al. Positional identification of Ncf1 as a gene that regulates arthritis severity in rats , 2003, Nature Genetics.
[44] R. Jonsson,et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans , 2002, Nature Genetics.
[45] A. Gottlieb,et al. TNF-alpha and apoptosis: implications for the pathogenesis and treatment of psoriasis. , 2002, Journal of drugs in dermatology : JDD.
[46] James G. Krueger,et al. Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis , 1995, Nature Genetics.
[47] James T. Elder,et al. Genetic epidemiology of psoriasis and psoriatic arthritis , 2005, Annals of the rheumatic diseases.
[48] P. Parren,et al. Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model. , 2003, The Journal of clinical investigation.