MicroRNA-503 regulates hypoxia-induced cardiomyocytes apoptosis through PI3K/Akt pathway by targeting IGF-1R.

[1]  Xianbao Wang,et al.  Hesperetin post-treatment prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating PI3K/Akt signaling pathway. , 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[2]  Lubo Zhang,et al.  MicroRNA-210 suppresses glucocorticoid receptor expression in response to hypoxia in fetal rat cardiomyocytes , 2017, Oncotarget.

[3]  Lubo Zhang,et al.  MicroRNA-210 suppresses glucocorticoid receptor expression in response to hypoxia in fetal rat cardiomyocytes , 2017, Oncotarget.

[4]  Chunmei Liu,et al.  Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis. , 2016, International journal of molecular medicine.

[5]  Chao Yang,et al.  MiR-503 inhibits hepatocellular carcinoma cell growth via inhibition of insulin-like growth factor 1 receptor , 2016, OncoTargets and therapy.

[6]  Weinan Wang,et al.  Flavonoids Extraction from Propolis Attenuates Pathological Cardiac Hypertrophy through PI3K/AKT Signaling Pathway , 2016, Evidence-based complementary and alternative medicine : eCAM.

[7]  Xiaojun Cui,et al.  Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways , 2016, Bioscience reports.

[8]  Ming Shao,et al.  MicroRNA-503 represses epithelial–mesenchymal transition and inhibits metastasis of osteosarcoma by targeting c-myb , 2016, Tumor Biology.

[9]  H. Shan,et al.  MicroRNA‐503 promotes angiotensin II‐induced cardiac fibrosis by targeting Apelin‐13 , 2016, Journal of cellular and molecular medicine.

[10]  Fei Li,et al.  Association between dietary patterns and coronary heart disease: a meta-analysis of prospective cohort studies. , 2015, International journal of clinical and experimental medicine.

[11]  Mark A Pereira,et al.  Smoking and risk of coronary heart disease in younger, middle-aged, and older adults. , 2014, American journal of public health.

[12]  Jia Liu,et al.  The Protective Effect of MicroRNA-320 on Left Ventricular Remodeling after Myocardial Ischemia-Reperfusion Injury in the Rat Model , 2014, International journal of molecular sciences.

[13]  Jian Chen,et al.  Calycosin Suppresses Breast Cancer Cell Growth via ERβ-Dependent Regulation of IGF-1R, p38 MAPK and PI3K/Akt Pathways , 2014, PloS one.

[14]  J. Xu,et al.  miR-503 regulates the resistance of non-small cell lung cancer cells to cisplatin by targeting Bcl-2. , 2013, International journal of molecular medicine.

[15]  Haiyang Xie,et al.  MicroRNA-503 inhibits the G1/S transition by downregulating cyclin D3 and E2F3 in hepatocellular carcinoma , 2013, Journal of Translational Medicine.

[16]  Ji-Ming Ye,et al.  TanshinoneIIA and Cryptotanshinone Protect against Hypoxia-Induced Mitochondrial Apoptosis in H9c2 Cells , 2013, PloS one.

[17]  K. Webster Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen species. , 2012, Future cardiology.

[18]  T. Ochiya,et al.  [Intracellular and extracellular microRNAs in human cancer]. , 2012, Nihon rinsho. Japanese journal of clinical medicine.

[19]  Jian Wang,et al.  The function of miRNA in cardiac hypertrophy , 2012, Cellular and Molecular Life Sciences.

[20]  Yong Liu,et al.  Neuregulin-1 suppresses cardiomyocyte apoptosis by activating PI3K/Akt and inhibiting mitochondrial permeability transition pore , 2012, Molecular and Cellular Biochemistry.

[21]  Bo Yu,et al.  Picroside II protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis by activating the PI3K/Akt and CREB pathways. , 2012, International journal of molecular medicine.

[22]  Li Lin,et al.  Overexpression of microRNA-378 attenuates ischemia-induced apoptosis by inhibiting caspase-3 expression in cardiac myocytes , 2012, Apoptosis.

[23]  Thomas Thum,et al.  Review focus on the role of microRNA in cardiovascular biology and disease. , 2012, Cardiovascular research.

[24]  D. Torella,et al.  Physiological cardiac remodelling in response to endurance exercise training: cellular and molecular mechanisms , 2011, Heart.

[25]  X. Chen,et al.  Identification of MicroRNAs Involved in Hypoxia- and Serum Deprivation-Induced Apoptosis in Mesenchymal Stem Cells , 2011, International journal of biological sciences.

[26]  P. Peixoto,et al.  Is mPTP the gatekeeper for necrosis, apoptosis, or both? , 2011, Biochimica et biophysica acta.

[27]  G. Condorelli,et al.  Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia , 2011, Circulation.

[28]  Damien Kee,et al.  Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K. , 2010, Cancer cell.

[29]  R. Ritchie,et al.  Cardiac-Specific IGF-1 Receptor Transgenic Expression Protects Against Cardiac Fibrosis and Diastolic Dysfunction in a Mouse Model of Diabetic Cardiomyopathy , 2010, Diabetes.

[30]  D. Glavač,et al.  MicroRNA Microarray Expression Profiling in Human Myocardial Infarction , 2010, Disease markers.

[31]  Thomas Thum,et al.  MicroRNAs: novel regulators in cardiac development and disease. , 2008, Cardiovascular research.

[32]  C. Bearzi,et al.  Activation of Cardiac Progenitor Cells Reverses the Failing Heart Senescent Phenotype and Prolongs Lifespan , 2008, Circulation research.

[33]  E. Jacobs,et al.  Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia. , 2008, American journal of physiology. Heart and circulatory physiology.

[34]  L. Helman,et al.  Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism , 2007, Oncogene.

[35]  K. Kinnally,et al.  Is MAC the knife that cuts cytochrome c from mitochondria during apoptosis? , 2006, Cell Death and Differentiation.

[36]  D. Kang,et al.  Mitochondrial DNA Damage and Dysfunction Associated With Oxidative Stress in Failing Hearts After Myocardial Infarction , 2001, Circulation research.

[37]  A. Almasan,et al.  Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis. , 2015, Methods in molecular biology.

[38]  J. Cheng,et al.  Identification of miRNAs associated with tumorigenesis of retinoblastoma by miRNA microarray analysis , 2008, Child's Nervous System.

[39]  J. Erdmann,et al.  Genetics and heritability of coronary artery disease and myocardial infarction , 2006, Clinical Research in Cardiology.