Induction of innate immune memory: the role of cellular metabolism.

[1]  M. Netea,et al.  Long‐term reprogramming of the innate immune system , 2018, Journal of leukocyte biology.

[2]  Edward T Chouchani,et al.  Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 , 2018, Nature.

[3]  Maxim N. Artyomov,et al.  Irg1 expression in myeloid cells prevents immunopathology during M. tuberculosis infection , 2018, The Journal of experimental medicine.

[4]  Maxim N. Artyomov,et al.  Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis , 2018, Nature.

[5]  M. Staufenbiel,et al.  Innate immune memory in the brain shapes neurological disease hallmarks , 2018, Nature.

[6]  L. Joosten,et al.  The Potential Role of Trained Immunity in Autoimmune and Autoinflammatory Disorders , 2018, Front. Immunol..

[7]  H. Young,et al.  Early TCR Signaling Induces Rapid Aerobic Glycolysis Enabling Distinct Acute T Cell Effector Functions , 2018, Cell reports.

[8]  L. O’Neill,et al.  A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation , 2018, Front. Immunol..

[9]  R. Horst,et al.  Metabolic Induction of Trained Immunity through the Mevalonate Pathway , 2018, Cell.

[10]  Irah L. King,et al.  BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis , 2018, Cell.

[11]  M. Oosting,et al.  Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming , 2018, Cell.

[12]  L. Joosten,et al.  Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity , 2018, Cell.

[13]  R. Xavier,et al.  BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. , 2018, Cell host & microbe.

[14]  E. McNeill,et al.  Metabolic Regulation of Adipose Tissue Macrophage Function in Obesity and Diabetes , 2017, Antioxidants & redox signaling.

[15]  R. Souza,et al.  Elevated d-2-hydroxyglutarate during colitis drives progression to colorectal cancer , 2018, Proceedings of the National Academy of Sciences.

[16]  M. Netea,et al.  Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses , 2018, Diabetologia.

[17]  Xian Wang,et al.  HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages , 2017, Mediators of inflammation.

[18]  Richard A. Notebaart,et al.  Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis , 2017, PLoS pathogens.

[19]  O. Rom,et al.  Atherogenicity of amino acids in the lipid-laden macrophage model system in vitro and in atherosclerotic mice: a key role for triglyceride metabolism. , 2017, The Journal of nutritional biochemistry.

[20]  D. Viemann,et al.  S100-alarmin-induced innate immune programming protects newborn infants from sepsis , 2017, Nature Immunology.

[21]  L. Joosten,et al.  Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway , 2017, Proceedings of the National Academy of Sciences.

[22]  L. Joosten,et al.  Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes , 2016, Nature Microbiology.

[23]  Richard A. Notebaart,et al.  Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. , 2016, Cell metabolism.

[24]  Vivien A. C. Schoonenberg,et al.  β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance , 2016, Cell.

[25]  A. D. de Vos,et al.  Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages. , 2016, Cell reports.

[26]  J. Rathmell,et al.  A guide to immunometabolism for immunologists , 2016, Nature Reviews Immunology.

[27]  E. Latz,et al.  Long-term activation of the innate immune system in atherosclerosis. , 2016, Seminars in immunology.

[28]  R. Mostoslavsky,et al.  Interplay between Metabolism and Epigenetics: A Nuclear Adaptation to Environmental Changes. , 2016, Molecular cell.

[29]  L. Joosten,et al.  Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis , 2016, Nature Immunology.

[30]  M. Ares,et al.  Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression , 2016, Nature Communications.

[31]  E. Pearce,et al.  Immunometabolism governs dendritic cell and macrophage function , 2016, The Journal of experimental medicine.

[32]  Robert A. Amezquita,et al.  IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity , 2015, Cell.

[33]  R. Xavier,et al.  Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity , 2014, Science.

[34]  R. Xavier,et al.  mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity , 2014, Science.

[35]  L. Joosten,et al.  Oxidized Low-Density Lipoprotein Induces Long-Term Proinflammatory Cytokine Production and Foam Cell Formation via Epigenetic Reprogramming of Monocytes , 2014, Arteriosclerosis, thrombosis, and vascular biology.

[36]  S. Nessler,et al.  Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection , 2014, Journal of Neuroinflammation.

[37]  R. Marmorstein,et al.  Structure and mechanism of non‐histone protein acetyltransferase enzymes , 2013, The FEBS journal.

[38]  M. Hersberger,et al.  Fatty acid–induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis , 2013, Nature Immunology.

[39]  Christine E. Becker,et al.  CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation , 2013, Nature Immunology.

[40]  M. Netea,et al.  Dectin-1 plays a redundant role in the immunomodulatory activities of β-glucan-rich ligands in vivo , 2013, Microbes and infection.

[41]  Liang Zheng,et al.  Succinate is an inflammatory signal that induces IL-1β through HIF-1α , 2013, Nature.

[42]  Hui Yang,et al.  Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. , 2012, Genes & development.

[43]  Takashi Tsukamoto,et al.  Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. , 2012, Cell metabolism.

[44]  M. Netea,et al.  Trained immunity: a memory for innate host defense. , 2011, Cell host & microbe.

[45]  Bin Wang,et al.  Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. , 2011, Cancer cell.

[46]  Justin R. Cross,et al.  ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation , 2009, Science.

[47]  E. Pivovarova,et al.  Lipid synthesis in macrophages during inflammation in vivo: Effect of agonists of peroxisome proliferator activated receptors α and γ and of retinoid X receptors , 2008, Biochemistry (Moscow).

[48]  L. McHeyzer-Williams,et al.  Antigen-specific memory B cell development. , 2005, Annual review of immunology.

[49]  J. Loscalzo Adverse effects of supplemental L-arginine in atherosclerosis: consequences of methylation stress in a complex catabolism? , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[50]  J. Remington,et al.  Effects of muramyl dipeptide treatment on resistance to infection with Toxoplasma gondii in mice , 1981, Infection and immunity.