mutant mice Lymphoid apoptosis and myeloid hyperplasia in CCAAT displacement protein

[1]  N. Moon,et al.  CCAAT Displacement Activity Involves CUT Repeats 1 and 2, Not the CUT Homeodomain* , 2000, The Journal of Biological Chemistry.

[2]  B. Jacobsen,et al.  YY1 Binds Five cis-Elements and Trans-activates the Myeloid Cell-restricted gp91 phox Promoter* , 1999, The Journal of Biological Chemistry.

[3]  S. Scherer,et al.  Delineation of multiple deleted regions in 7q in myeloid disorders , 1999, Genes, chromosomes & cancer.

[4]  G. Kollias,et al.  Effects of hTNFα expression in T cells on haematopoiesis in transgenic mice , 1999 .

[5]  E. Neufeld,et al.  Transcriptional Repression of the Cystic Fibrosis Transmembrane Conductance Regulator Gene, Mediated by CCAAT Displacement Protein/cut Homolog, Is Associated with Histone Deacetylation* , 1999, The Journal of Biological Chemistry.

[6]  P. Watson,et al.  Refined mapping of the region of loss of heterozygosity on the long arm of chromosome 7 in human breast cancer defines the location of a second tumor suppressor gene at 7q22 in the region of the CUTL1 gene , 1999, Oncogene.

[7]  R. Scheuermann,et al.  Cux/CDP Homeoprotein Is a Component of NF-μNR and Represses the Immunoglobulin Heavy Chain Intronic Enhancer by Antagonizing the Bright Transcription Activator , 1999, Molecular and Cellular Biology.

[8]  X Zhang,et al.  Bcr-Abl efficiently induces a myeloproliferative disease and production of excess interleukin-3 and granulocyte-macrophage colony-stimulating factor in mice: a novel model for chronic myelogenous leukemia. , 1998, Blood.

[9]  Jianzhu Chen,et al.  A Nuclear Matrix Attachment Region Upstream of the T Cell Receptor β Gene Enhancer Binds Cux/CDP and SATB1 and Modulates Enhancer-dependent Reporter Gene Expression but Not Endogenous Gene Expression* , 1998, The Journal of Biological Chemistry.

[10]  K. Calame,et al.  Evidence that Immunoglobulin VH-DJ Recombination Does Not Require Germ Line Transcription of the Recombining Variable Gene Segment , 1998, Molecular and Cellular Biology.

[11]  E. Neufeld,et al.  Hair defects and pup loss in mice with targeted deletion of the first cut repeat domain of the Cux/CDP homeoprotein gene. , 1998, Developmental biology.

[12]  N. Lawson,et al.  Isolation and characterization of the cDNA for mouse neutrophil collagenase: demonstration of shared negative regulatory pathways for neutrophil secondary granule protein gene expression. , 1998, Blood.

[13]  P. Nowell,et al.  Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[14]  E. Neufeld,et al.  CCAAT displacement protein (CDP/cut) recognizes a silencer element within the lactoferrin gene promoter. , 1997, Blood.

[15]  R. Kobayashi,et al.  Interaction of the Nuclear Matrix-associated Region (MAR)-Binding Proteins, SATB1 and CDP/Cux, with a MAR Element (L2a) in an Upstream Regulatory Region of the Mouse CD8a Gene* , 1997, The Journal of Biological Chemistry.

[16]  U. Surti,et al.  Two discrete regions of deletion at 7q in uterine leiomyomas , 1997, Genes, chromosomes & cancer.

[17]  S. Scherer,et al.  Loss of heterozygosity and reduced expression of the CUTL1 gene in uterine leiomyomas , 1997, Oncogene.

[18]  C. Tribioli,et al.  Acute leukemia with promyelocytic features in PML/RARα transgenic mice , 1997 .

[19]  S. Scherer,et al.  Molecular cytogenetic delineation of deletions and translocations involving chromosome band 7q22 in myeloid leukemias. , 1997, Blood.

[20]  S. Phillips,et al.  The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy , 1996, Molecular and cellular biology.

[21]  W. Luo,et al.  CCAAT Displacement Protein Competes with Multiple Transcriptional Activators for Binding to Four Sites in the Proximal gp91phox Promoter* , 1996, The Journal of Biological Chemistry.

[22]  F. Alt,et al.  Gene-targeted deletion and replacement mutations of the T-cell receptor beta-chain enhancer: the role of enhancer elements in controlling V(D)J recombination accessibility. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[23]  F. Watrin,et al.  Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[24]  M. Wabl,et al.  A Quasi-Monoclonal Mouse , 1996, Science.

[25]  S. Scherer,et al.  Molecular definition of a narrow interval at 7q22.1 associated with myelodysplasia. , 1996, Blood.

[26]  J. Boultwood,et al.  Molecular characterization of the 7q deletion in myeloid disorders , 1996, British journal of haematology.

[27]  R. Scheuermann,et al.  Mutually exclusive interaction of a novel matrix attachment region binding protein and the NF-muNR enhancer repressor. Implications for regulation of immunoglobulin heavy chain expression. , 1995, The Journal of biological chemistry.

[28]  M. Lenardo,et al.  Requirement for TNF-alpha and IL-1 alpha in fetal thymocyte commitment and differentiation. , 1995, Science.

[29]  A. Nepveu,et al.  DNA-binding specificity of the cut repeats from the human cut-like protein , 1995, Molecular and cellular biology.

[30]  E. Wagner,et al.  Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5 BSAP , 1994, Cell.

[31]  E. Neufeld,et al.  Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[32]  S. Yoon,et al.  Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer. , 1994, The Journal of biological chemistry.

[33]  M. Krangel,et al.  Temporal and lineage-specific control of T cell receptor alpha/delta gene rearrangement by T cell receptor alpha and delta enhancers , 1994, The Journal of experimental medicine.

[34]  P. Ferrier,et al.  Sequences affecting the V(D)J recombinational activity of the IgH intronic enhancer in a transgenic substrate. , 1994, Nucleic acids research.

[35]  D. Dufort,et al.  Conserved cut repeats in the human cut homeodomain protein function as DNA binding domains. , 1994, The Journal of biological chemistry.

[36]  C. Goridis,et al.  The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. , 1993, Development.

[37]  B. Nadal-Ginard,et al.  Clox, a mammalian homeobox gene related to Drosophila cut, encodes DNA-binding regulatory proteins differentially expressed during development. , 1992, Development.

[38]  S. Orkin,et al.  Human CCAAT displacement protein is homologous to the Drosophila homeoprotein, cut , 1992, Nature Genetics.

[39]  V. Stewart,et al.  RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement , 1992, Cell.

[40]  D. Dorsett,et al.  Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancer. , 1991, Development.

[41]  S. Orkin,et al.  CCAAT displacement protein as a repressor of the myelomonocytic-specific gp91-phox gene promoter. , 1991, The Journal of biological chemistry.

[42]  Y. Jan,et al.  Transformation of sensory organ identity by ectopic expression of Cut in Drosophila. , 1991, Genes & development.

[43]  R. Scheuermann,et al.  A developmental-specific factor binds to suppressor sites flanking the immunoglobulin heavy-chain enhancer. , 1989, Genes & development.

[44]  M. Ogawa,et al.  B cell ontogeny in murine embryo studied by a culture system with the monolayer of a stromal cell clone, ST2: B cell progenitor develops first in the embryonal body rather than in the yolk sac. , 1988, The EMBO journal.

[45]  Y. Jan,et al.  Transformation of sensory organs by Mutations of the cut locus of D. melanogaster , 1987, Cell.

[46]  G. Superti-Furga,et al.  Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter , 1987, Cell.

[47]  D. Baltimore,et al.  Molecular basis of a mouse strain-specific anti-hapten response , 1983, Cell.

[48]  R. Scheuermann,et al.  MARs of antigen receptor and co-receptor genes. , 1999, Critical reviews in eukaryotic gene expression.

[49]  R. Scheuermann,et al.  Differential regulation of immunoglobulin gene transcription via nuclear matrix-associated regions. , 1999, Cold Spring Harbor symposia on quantitative biology.

[50]  C. Ware,et al.  Apoptosis mediated by the TNF‐related cytokine and receptor families , 1996, Journal of cellular biochemistry.

[51]  P. Vassalli,et al.  The pathophysiology of tumor necrosis factors. , 1992, Annual review of immunology.

[52]  I. Lefkovits.  Limiting Dilution Analysis , 1979 .