Cyclosporine for Adult Onset Still's Disease Flare with Hepatic Dysfunction

We report on a 27 year-old man with adult onset Still’s disease (AOSD) who had a flare after two years of management with methotrexate (MTX) and prednisolone. The clinical manifestations included hepatitis, jaundice, fever and atypical skin rash. Because of hepatitic dysfucntion, cyclosporine was prescribed instead of MTX. After therapy with cyclosporine, the patient recovered with improved liver enzymes and clinical features.

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