A variable resolution approach for improved acquisition of hyperpolarized 13C metabolic MRI

To ameliorate tradeoffs between a fixed spatial resolution and signal‐to‐noise ratio (SNR) for hyperpolarized 13C MRI.

[1]  Albert P. Chen,et al.  Lactate topography of the human brain using hyperpolarized 13C-MRI , 2020, NeuroImage.

[2]  Ed Reznik,et al.  Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1. , 2020, Cell metabolism.

[3]  Frank Riemer,et al.  Quantifying normal human brain metabolism using hyperpolarized [1–13C]pyruvate and magnetic resonance imaging , 2019, NeuroImage.

[4]  Shuyu Tang,et al.  Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies. , 2019, Journal of magnetic resonance.

[5]  Lucio Frydman,et al.  Enhanced hyperpolarized chemical shift imaging based on a priori segmented information , 2018, Magnetic resonance in medicine.

[6]  Rahul Aggarwal,et al.  Translation of Carbon‐13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients , 2018, Magnetic resonance in medicine.

[7]  Shuyu Tang,et al.  A regional bolus tracking and real‐time B1 calibration method for hyperpolarized 13C MRI , 2018, Magnetic resonance in medicine.

[8]  A. Venkatesan,et al.  Influence of parameter accuracy on pharmacokinetic analysis of hyperpolarized pyruvate , 2018, Magnetic resonance in medicine.

[9]  G. Jeong,et al.  Metabolic alterations in a rat model of hepatic ischaemia reperfusion injury: In vivo hyperpolarized 13C MRS and metabolic imaging , 2018, Liver international : official journal of the International Association for the Study of the Liver.

[10]  Charles H Cunningham,et al.  Dual‐Echo EPI sequence for integrated distortion correction in 3D time‐resolved hyperpolarized 13C MRI , 2018, Magnetic resonance in medicine.

[11]  Rahul Aggarwal,et al.  Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Androgen Ablation Therapy in Prostate Cancer. , 2017, European urology.

[12]  Dong-Hyun Kim,et al.  Flow‐suppressed hyperpolarized 13C chemical shift imaging using velocity‐optimized bipolar gradient in mouse liver tumors at 9.4 T , 2017, Magnetic resonance in medicine.

[13]  E. Warburton,et al.  PET imaging of the neurovascular interface in cerebrovascular disease , 2017, Nature Reviews Neurology.

[14]  John M Pauly,et al.  Spectrally selective three‐dimensional dynamic balanced steady‐state free precession for hyperpolarized C‐13 metabolic imaging with spectrally selective radiofrequency pulses , 2017, Magnetic resonance in medicine.

[15]  Caroline Guglielmetti,et al.  Hyperpolarized 13C MR metabolic imaging can detect neuroinflammation in vivo in a multiple sclerosis murine model , 2017, Proceedings of the National Academy of Sciences.

[16]  Damian J Tyler,et al.  Susceptibility‐induced distortion correction in hyperpolarized echo planar imaging , 2017, Magnetic resonance in medicine.

[17]  S. Kozerke,et al.  Hyperpolarized 13C urea myocardial first-pass perfusion imaging using velocity-selective excitation , 2017, Journal of Cardiovascular Magnetic Resonance.

[18]  John Kurhanewicz,et al.  Assessing Prostate Cancer Aggressiveness with Hyperpolarized Dual-Agent 3D Dynamic Imaging of Metabolism and Perfusion. , 2017, Cancer research.

[19]  Daniel B Vigneron,et al.  Development of a symmetric echo planar imaging framework for clinical translation of rapid dynamic hyperpolarized 13C imaging , 2017, Magnetic resonance in medicine.

[20]  Graham A. Wright,et al.  Hyperpolarized 13C Metabolic MRI of the Human Heart , 2016, Circulation research.

[21]  Jeremy W. Gordon,et al.  Optimizing Flip Angles for Metabolic Rate Estimation in Hyperpolarized Carbon-13 MRI , 2016, IEEE Transactions on Medical Imaging.

[22]  Kevin M. Johnson,et al.  Application of flow sensitive gradients for improved measures of metabolism using hyperpolarized 13c MRI , 2016, Magnetic resonance in medicine.

[23]  T. Jang,et al.  Volumetric spiral chemical shift imaging of hyperpolarized [2‐13c]pyruvate in a rat c6 glioma model , 2016, Magnetic resonance in medicine.

[24]  Matthew D. Robson,et al.  Cardiac perfusion imaging using hyperpolarized 13c urea using flow sensitizing gradients , 2015, Magnetic resonance in medicine.

[25]  Peter Bachert,et al.  Partial volume correction for in vivo 23Na-MRI data of the human brain , 2015, NeuroImage.

[26]  P. Larson,et al.  Noninvasive In Vivo Imaging of Diabetes-Induced Renal Oxidative Stress and Response to Therapy Using Hyperpolarized 13C Dehydroascorbate Magnetic Resonance , 2014, Diabetes.

[27]  J. Maddahi,et al.  Cardiac PET perfusion tracers: current status and future directions. , 2014, Seminars in nuclear medicine.

[28]  G Wilson Miller,et al.  Regional mapping of gas uptake by blood and tissue in the human lung using hyperpolarized xenon‐129 MRI , 2014, Journal of magnetic resonance imaging : JMRI.

[29]  Y. Yen,et al.  Effects of isoflurane anesthesia on hyperpolarized 13C metabolic measurements in rat brain , 2013, Magnetic resonance in medicine.

[30]  Adam B Kerr,et al.  Optimal variable flip angle schemes for dynamic acquisition of exchanging hyperpolarized substrates. , 2013, Journal of magnetic resonance.

[31]  P. Larson,et al.  Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1-13C]Pyruvate , 2013, Science Translational Medicine.

[32]  Ricardo Otazo,et al.  MR spectroscopic imaging: Principles and recent advances , 2013, Journal of magnetic resonance imaging : JMRI.

[33]  Florian Wiesinger,et al.  Saturation‐recovery metabolic‐exchange rate imaging with hyperpolarized [1‐13C] pyruvate using spectral‐spatial excitation , 2013, Magnetic resonance in medicine.

[34]  P. Larson,et al.  Rapid sequential injections of hyperpolarized [1-¹³C]pyruvate in vivo using a sub-kelvin, multi-sample DNP polarizer. , 2013, Magnetic resonance imaging.

[35]  A. Alavi,et al.  PET/MR imaging: technical aspects and potential clinical applications. , 2013, Radiology.

[36]  Mark W. Woolrich,et al.  RubiX: Combining Spatial Resolutions for Bayesian Inference of Crossing Fibers in Diffusion MRI , 2013, IEEE Transactions on Medical Imaging.

[37]  Klaus Scheffler,et al.  Fast metabolite mapping in the pig heart after injection of hyperpolarized 13C‐pyruvate with low‐flip angle balanced steady‐state free precession imaging , 2012, Magnetic resonance in medicine.

[38]  Peder E. Z. Larson,et al.  Generating Super Stimulated-Echoes in MRI and Their Application to Hyperpolarized C-13 Diffusion Metabolic Imaging , 2012, IEEE Transactions on Medical Imaging.

[39]  W. Moses Fundamental Limits of Spatial Resolution in PET. , 2011, Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment.

[40]  Graham A Wright,et al.  Rapid multislice imaging of hyperpolarized 13C pyruvate and bicarbonate in the heart , 2010, Magnetic resonance in medicine.

[41]  John Kurhanewicz,et al.  Multi-compound polarization by DNP allows simultaneous assessment of multiple enzymatic activities in vivo. , 2010, Journal of magnetic resonance.

[42]  Albert P. Chen,et al.  Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading. , 2008, Cancer research.

[43]  Michael Lustig,et al.  Pulse sequence for dynamic volumetric imaging of hyperpolarized metabolic products. , 2008, Journal of magnetic resonance.

[44]  J. Ardenkjær-Larsen,et al.  Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[45]  P. Boesiger,et al.  Advances in sensitivity encoding with arbitrary k‐space trajectories , 2001, Magnetic resonance in medicine.

[46]  T J Brady,et al.  Cardiac susceptibility artifacts arising from the heart‐lung interface , 2001, Magnetic resonance in medicine.

[47]  E R McVeigh,et al.  In vivo measurement of T*2 and field inhomogeneity maps in the human heart at 1.5 T , 1998, Magnetic resonance in medicine.

[48]  W. Edelstein,et al.  The intrinsic signal‐to‐noise ratio in NMR imaging , 1986, Magnetic resonance in medicine.

[49]  A. Macovski,et al.  Selection of a convolution function for Fourier inversion using gridding [computerised tomography application]. , 1991, IEEE transactions on medical imaging.