Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms.
暂无分享,去创建一个
R. Kiessling | J. Hansson | I. Schultz | G. Masucci | A. Lundqvist | E. Wennerberg | S. Egyházi Brage | I. Poschke | Yago Pico de Coaña | Yumeng Mao
[1] N. Munshi,et al. Tumor-promoting immune-suppressive myeloid-derived suppressor cells in the multiple myeloma microenvironment in humans. , 2013, Blood.
[2] P. Kalinski,et al. Generation of myeloid-derived suppressor cells using prostaglandin E2 , 2012, Transplantation research.
[3] R. Kiessling,et al. On the armament and appearances of human myeloid-derived suppressor cells. , 2012, Clinical immunology.
[4] K. Odunsi,et al. PGE2-Driven Induction and Maintenance of Cancer-Associated Myeloid-Derived Suppressor Cells , 2012, Immunological investigations.
[5] S. Rosenberg,et al. Myeloid Cells Obtained from the Blood but Not from the Tumor Can Suppress T-cell Proliferation in Patients with Melanoma , 2012, Clinical Cancer Research.
[6] N. Jhala,et al. Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. , 2012, Cancer cell.
[7] D. Bar-Sagi,et al. Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia. , 2012, Cancer cell.
[8] R. Kiessling,et al. Myeloid-derived suppressor cells impair the quality of dendritic cell vaccines , 2012, Cancer Immunology, Immunotherapy.
[9] C. Drake,et al. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. , 2012, Current opinion in immunology.
[10] K. Odunsi,et al. PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment. , 2011, Cancer research.
[11] R. Edwards,et al. Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. , 2011, Blood.
[12] A. Rosato,et al. A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells. , 2011, Blood.
[13] A. Epstein,et al. Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines , 2011, Journal of Translational Medicine.
[14] P. Ascierto,et al. Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. , 2010, Seminars in oncology.
[15] A. Epstein,et al. Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells , 2010, The Journal of Immunology.
[16] S. Selvan,et al. Establishment of stable cell lines for personalized melanoma cell vaccine , 2010, Melanoma research.
[17] D. Mougiakakos,et al. Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign. , 2010, Cancer research.
[18] A. Dietz,et al. Normal human monocytes exposed to glioma cells acquire myeloid-derived suppressor cell-like properties. , 2010, Neuro-oncology.
[19] J. Ochoa,et al. Stat 6-Dependent Induction of Myeloid Derived Suppressor Cells After Physical Injury Regulates Nitric Oxide Response to Endotoxin , 2010, Annals of surgery.
[20] D. Mougiakakos,et al. Prognostic significance of tumor iNOS and COX-2 in stage III malignant cutaneous melanoma , 2009, Cancer Immunology, Immunotherapy.
[21] T. Padhya,et al. Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells1 , 2009, The Journal of Immunology.
[22] Yuan Zhang,et al. Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells , 2009, Cancer Immunology, Immunotherapy.
[23] P. Sinha,et al. Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer 1 , 2009, The Journal of Immunology.
[24] Srinivas Nagaraj,et al. Myeloid-derived suppressor cells as regulators of the immune system , 2009, Nature Reviews Immunology.
[25] Michelle Collazo,et al. Subsets of Myeloid-Derived Suppressor Cells in Tumor-Bearing Mice1 , 2008, The Journal of Immunology.
[26] V. Bronte,et al. Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells , 2008, Immunological reviews.
[27] P. De Baetselier,et al. Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. , 2008, Blood.
[28] C. O'brien,et al. Expression of COX-2 and Prognostic Outcome in Uveal Melanoma , 2008, Current eye research.
[29] L. Mariani,et al. Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[30] Wan-Wan Lin,et al. A cytokine-mediated link between innate immunity, inflammation, and cancer. , 2007, The Journal of clinical investigation.
[31] P. Sinha,et al. Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells. , 2007, Cancer research.
[32] O. Lesur,et al. GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals , 2007, Biogerontology.
[33] D. Gabrilovich,et al. Effect of tumor-derived cytokines and growth factors on differentiation and immune suppressive features of myeloid cells in cancer , 2006, Cancer and Metastasis Reviews.
[34] D. Stolz,et al. Modulation of Stat3 activation by the cytosolic phospholipase A2α and cyclooxygenase-2-controlled prostaglandin E2 signaling pathway. , 2006, The Journal of Biological Chemistry.
[35] Yuan Zhang,et al. CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells. , 2006, Cancer research.
[36] E. Hurt,et al. The role of IL-6 and STAT3 in inflammation and cancer. , 2005, European journal of cancer.
[37] Daniele M. Gilkes,et al. Activation of Dendritic Cells via Inhibition of Jak2/STAT3 Signaling1 , 2005, The Journal of Immunology.
[38] R. Kiessling,et al. Autocrine Secretion of Fas Ligand Shields Tumor Cells from Fas-Mediated Killing by Cytotoxic Lymphocytes , 2004, Cancer Research.
[39] V. Bronte,et al. High-Dose Granulocyte-Macrophage Colony-Stimulating Factor-Producing Vaccines Impair the Immune Response through the Recruitment of Myeloid Suppressor Cells , 2004, Cancer Research.
[40] A. Sharpe,et al. CD80+Gr-1+ Myeloid Cells Inhibit Development of Antifungal Th1 Immunity in Mice with Candidiasis1 , 2002, The Journal of Immunology.
[41] J. Gamble,et al. Roles of Cyclooxygenase (COX)-1 and COX-2 in Prostanoid Production by Human Endothelial Cells: Selective Up-Regulation of Prostacyclin Synthesis by COX-21 , 2001, The Journal of Immunology.
[42] G. Freeman,et al. Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation , 2000, The Journal of experimental medicine.
[43] G. Zhu,et al. B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion , 1999, Nature Medicine.
[44] D. Gabrilovich,et al. Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. , 2011, Trends in immunology.
[45] C. Denkert,et al. Expression of cyclooxygenase 2 in human malignant melanoma. , 2001, Cancer research.