Rethinking the Use of Auditory Brainstem Response in Acoustic Neuroma Screening

The ability of magnetic resonance imaging (MRI) to detect very small acoustic tumors has triggered many to rethink the use of auditory brainstem response (ABR) in the screening of acoustic tumors. To assess ABR accuracy, we conducted a retrospective study of 388 surgically treated patients. Of these patients, 111 had complete databases including both preoperative MRIs and ABRs. The ABR was abnormal by wave V interaural latency difference in 106 (95%) of the cases. Although our overall sensitivity was 95%, sensitivity varied according to tumor size. ABR was abnormal or absent for all tumors (100%) larger than 2 cm in diameter, for 98% of tumors 1.1 to 2 cm in diameter, and for only 89% of tumors less than or equal to 1 cm in diameter. Ramifications of this in the decision‐making process are presented. Criteria for cut‐off values are also discussed.

[1]  S. Chandrasekhar,et al.  Utility of auditory brainstem response audiometry in diagnosis of acoustic neuromas. , 1995, The American journal of otology.

[2]  W. Lippy,et al.  Acoustic Reflexes, Auditory Brainstem Response, and MRI in the Evaluation of Acoustic Neuromas , 1996, The Laryngoscope.

[3]  D. Welling,et al.  Acoustic Neuroma: A Cost-Effective Approach , 1990, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[4]  J. Helms,et al.  Hearing preservation in acoustic tumor surgery: Results and prognostic factors , 1995, The Laryngoscope.

[5]  W. House,et al.  Acoustic tumor surgery. Prognostic factors in hearing conversation. , 1989, Archives of otolaryngology--head & neck surgery.

[6]  D L Jewett,et al.  Human Auditory Evoked Potentials: Possible Brain Stem Components Detected on the Scalp , 1970, Science.

[7]  C. Shelton Hearing preservation in acoustic tumor surgery. , 1992, Otolaryngologic clinics of North America.

[8]  W. House,et al.  Changing concepts of acoustic neuroma diagnosis. , 1985, Archives of otolaryngology.

[9]  D. Brackmann,et al.  Acoustic tumor detection with brain stem electric response audiometry. , 1977, Archives of otolaryngology.

[10]  M. Graham,et al.  Normal auditory brainstem response in patients with acoustic neuroma , 1989, The Laryngoscope.

[11]  J. Clemis,et al.  Brain stem electric response audiometry in the differential diagnosis of acoustic tumors , 1979, The Laryngoscope.

[12]  David F. Wilson,et al.  The sensitivity of auditory brainstem response testing in small acoustic neuromas , 1992, The Laryngoscope.

[13]  N. Cohen,et al.  Efficacy of auditory brainstem response as a screening test for small acoustic neuromas. , 1995, The American journal of otology.

[14]  A. Robson,et al.  MRI as a Single Screening Procedure for Acoustic Neuroma: A Cost Effective Protocol , 1993, Journal of the Royal Society of Medicine.