Cardiopulmonary Resuscitation Quality: Improving Cardiac Resuscitation Outcomes Both Inside and Outside the Hospital A Consensus Statement From the American Heart Association

The "2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care" increased the focus on methods to ensure that high-quality cardiopulmonary resuscitation (CPR) is performed in all resuscitation attempts. There are 5 critical components of high-quality CPR: minimize interruptions in chest compressions, provide compressions of adequate rate and depth, avoid leaning between compressions, and avoid excessive ventilation. Although it is clear that high-quality CPR is the primary component in influencing survival from cardiac arrest, there is considerable variation in monitoring, implementation, and quality improvement. As such, CPR quality varies widely between systems and locations. Victims often do not receive high-quality CPR because of provider ambiguity in prioritization of resuscitative efforts during an arrest. This ambiguity also impedes the development of optimal systems of care to increase survival from cardiac arrest. This consensus statement addresses the following key areas of CPR quality for the trained rescuer: metrics of CPR performance; monitoring, feedback, and integration of the patient’s response to CPR; team-level logistics to ensure performance of high-quality CPR; and continuous quality improvement on provider, team, and systems levels. Clear definitions of metrics and methods to consistently deliver and improve the quality of CPR will narrow the gap between resuscitation science and the victims, both in and out of the hospital, and lay the foundation for further improvements in the future.

[1]  B. Bobrow,et al.  The influence of scenario-based training and real-time audiovisual feedback on out-of-hospital cardiopulmonary resuscitation quality and survival from out-of-hospital cardiac arrest. , 2013, Annals of emergency medicine.

[2]  M. Ong,et al.  Improving the quality of cardiopulmonary resuscitation by training dedicated cardiac arrest teams incorporating a mechanical load-distributing device at the emergency department. , 2013, Resuscitation.

[3]  Kristy B Arbogast,et al.  American Heart Association cardiopulmonary resuscitation quality targets are associated with improved arterial blood pressure during pediatric cardiac arrest. , 2013, Resuscitation.

[4]  D. Chamberlain,et al.  The Study Protocol for the LINC (LUCAS in Cardiac Arrest) Study: a study comparing conventional adult out-of-hospital cardiopulmonary resuscitation with a concept with mechanical chest compressions and simultaneous defibrillation , 2013, Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine.

[5]  V. Nadkarni,et al.  Training hospital providers in basic CPR skills in Botswana: acquisition, retention and impact of novel training techniques. , 2012, Resuscitation.

[6]  D. Davis,et al.  Abstract 287: What Is the Optimal Chest Compression Depth During Resuscitation from Out-of-Hospital Cardiac Arrest in Adult Patients? , 2012 .

[7]  Steven M Bradley,et al.  Duration of hospital participation in Get With the Guidelines-Resuscitation and survival of in-hospital cardiac arrest. , 2012, Resuscitation.

[8]  K. Monsieurs,et al.  Excessive chest compression rate is associated with insufficient compression depth in prehospital cardiac arrest. , 2012, Resuscitation.

[9]  S. Chung,et al.  Precise minute ventilation delivery using a bag-valve mask and audible feedback. , 2012, The American journal of emergency medicine.

[10]  R. Berg,et al.  Evaluation of quantitative debriefing after pediatric cardiac arrest. , 2012, Resuscitation.

[11]  J. Soar,et al.  A systematic review of retention of adult advanced life support knowledge and skills in healthcare providers. , 2012, Resuscitation.

[12]  Henry E. Wang,et al.  Endotracheal intubation versus supraglottic airway insertion in out-of-hospital cardiac arrest. , 2012, Resuscitation.

[13]  G. Ong,et al.  Factors affecting team leadership skills and their relationship with quality of cardiopulmonary resuscitation* , 2012, Critical care medicine.

[14]  M. Kurz,et al.  Estimating the impact of off-balancing forces upon cardiopulmonary resuscitation during ambulance transport. , 2012, Resuscitation.

[15]  P. Pronovost,et al.  Preventing patient harms through systems of care. , 2012, JAMA.

[16]  F. Chapman,et al.  Assessment of CPR interruptions from transthoracic impedance during use of the LUCAS™ mechanical chest compression system. , 2012, Resuscitation.

[17]  Matthew R Maltese,et al.  Backboards are important when chest compressions are provided on a soft mattress. , 2012, Resuscitation.

[18]  Yun Kyung Cho,et al.  Induction of a shorter compression phase is correlated with a deeper chest compression during metronome-guided cardiopulmonary resuscitation: a manikin study , 2012, Emergency Medicine Journal.

[19]  E. Antman,et al.  Systems of Care for ST-Segment–Elevation Myocardial Infarction: A Report From the American Heart Association’s Mission: Lifeline , 2012, Circulation. Cardiovascular quality and outcomes.

[20]  D. Edelson,et al.  The impact of a step stool on cardiopulmonary resuscitation: a cross-over mannequin study. , 2012, Resuscitation.

[21]  D. Davis,et al.  Relationship Between Chest Compression Rates and Outcomes From Cardiac Arrest , 2012, Circulation.

[22]  H. Stelfox,et al.  Quality indicators used by trauma centers for performance measurement , 2012, The journal of trauma and acute care surgery.

[23]  C. Callaway,et al.  What is the role of chest compression depth during out-of-hospital cardiac arrest resuscitation?* , 2012, Critical care medicine.

[24]  R. Gazmuri,et al.  Clinically plausible hyperventilation does not exert adverse hemodynamic effects during CPR but markedly reduces end-tidal PCO₂. , 2012, Resuscitation.

[25]  Matthew R Maltese,et al.  Prevalence and hemodynamic effects of leaning during CPR. , 2011, Resuscitation.

[26]  Judy Powell,et al.  The impact of increased chest compression fraction on return of spontaneous circulation for out-of-hospital cardiac arrest patients not in ventricular fibrillation. , 2011, Resuscitation.

[27]  G. Perkins,et al.  Variability in cardiac arrest survival: the NHS Ambulance Service Quality Indicators , 2011, Emergency Medicine Journal.

[28]  S. Hunziker,et al.  Activities during interruptions in cardiopulmonary resuscitation: a simulator study. , 2011, Resuscitation.

[29]  Nandita Mitra,et al.  Incidence of treated cardiac arrest in hospitalized patients in the United States* , 2011, Critical care medicine.

[30]  H. Myklebust,et al.  Decay in chest compression quality due to fatigue is rare during prolonged advanced life support in a manikin model , 2011, Scandinavian journal of trauma, resuscitation and emergency medicine.

[31]  C. Trowbridge,et al.  A counterbalanced cross-over study of the effects of visual, auditory and no feedback on performance measures in a simulated cardiopulmonary resuscitation , 2011, BMC nursing.

[32]  Dana Niles,et al.  The prevalence of chest compression leaning during in-hospital cardiopulmonary resuscitation. , 2011, Resuscitation.

[33]  R. Berg,et al.  The first quantitative report of ventilation rate during in-hospital resuscitation of older children and adolescents. , 2011, Resuscitation.

[34]  Hajime Sato,et al.  Backboard insertion in the operating table increases chest compression depth: a manikin study , 2011, Journal of Anesthesia.

[35]  Judy Powell,et al.  Perishock Pause: An Independent Predictor of Survival From Out-of-Hospital Shockable Cardiac Arrest , 2011, Circulation.

[36]  Vinay Nadkarni,et al.  Low-Dose, High-Frequency CPR Training Improves Skill Retention of In-Hospital Pediatric Providers , 2011, Pediatrics.

[37]  Adam Almozlino,et al.  Cardiopulmonary resuscitation feedback improves the quality of chest compression provided by hospital health care professionals. , 2011, The American journal of emergency medicine.

[38]  D. Wijayatilake,et al.  Comparison of the Mapleson C system and adult and paediatric self‐inflating bags for delivering guideline‐consistent ventilation during simulated adult cardiopulmonary resuscitation * , 2011, Anaesthesia.

[39]  B. Steinlechner,et al.  A manually powered mechanical resuscitation device used by a single rescuer: a randomised controlled manikin study. , 2011, Resuscitation.

[40]  S. Hunziker,et al.  Teamwork and leadership in cardiopulmonary resuscitation. , 2011, Journal of the American College of Cardiology.

[41]  S. Rubertsson,et al.  A pilot study of mechanical chest compressions with the LUCAS™ device in cardiopulmonary resuscitation. , 2011, Resuscitation.

[42]  Marilyn H Oermann,et al.  Effects of monthly practice on nursing studentsâ€TM CPR psychomotor skill performance , 2011 .

[43]  C. Murray,et al.  Improving the public health utility of global cardiovascular mortality data: the rise of ischemic heart disease , 2011, Population health metrics.

[44]  Pamela Andreatta,et al.  Simulation-based mock codes significantly correlate with improved pediatric patient cardiopulmonary arrest survival rates* , 2011, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[45]  C. Havel,et al.  Quality of resuscitation: flight attendants in an airplane simulator use a new mechanical resuscitation device--a randomized simulation study. , 2010, Resuscitation.

[46]  G. Perkins,et al.  Prehospital randomised assessment of a mechanical compression device in cardiac arrest (PaRAMeDIC) trial protocol , 2010, Scandinavian journal of trauma, resuscitation and emergency medicine.

[47]  Robin Hemphill,et al.  Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. , 2010, Circulation.

[48]  Mark Terry,et al.  Part 13: pediatric basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. , 2010, Circulation.

[49]  Roger D. White,et al.  Part 8: adult advanced cardiovascular life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. , 2010, Circulation.

[50]  Bentley J Bobrow,et al.  Part 4: CPR overview: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. , 2010, Circulation.

[51]  Vinay M Nadkarni,et al.  Part 14: Pediatric Advanced Life Support , 2010 .

[52]  R. Berg,et al.  Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies. , 2010, Resuscitation.

[53]  M. Ong,et al.  Cardiopulmonary resuscitation interruptions with use of a load-distributing band device during emergency department cardiac arrest. , 2010, Annals of emergency medicine.

[54]  A. Kaji,et al.  Advanced airway management does not improve outcome of out-of-hospital cardiac arrest. , 2010, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[55]  Sun Wook Kim,et al.  Effect of vehicle speed on the quality of closed-chest compression during ambulance transport. , 2010, Resuscitation.

[56]  D. Davis,et al.  Minimizing pre- and post-defibrillation pauses increases the likelihood of return of spontaneous circulation (ROSC). , 2010, Resuscitation.

[57]  R. Berg,et al.  Effect of residual leaning force on intrathoracic pressure during mechanical ventilation in children. , 2010, Resuscitation.

[58]  How-Ran Guo,et al.  Rescuer fatigue and cardiopulmonary resuscitation positions: A randomized controlled crossover trial. , 2010, Resuscitation.

[59]  Vinay M. Nadkarni,et al.  Leaning during chest compressions impairs cardiac output and left ventricular myocardial blood flow in piglet cardiac arrest , 2010, Critical care medicine.

[60]  Franziska Tschan,et al.  Brief leadership instructions improve cardiopulmonary resuscitation in a high-fidelity simulation: A randomized controlled trial* , 2010, Critical care medicine.

[61]  R. Neumar,et al.  Regional systems of care for out-of-hospital cardiac arrest: A policy statement from the American Heart Association. , 2010, Circulation.

[62]  K. Kern,et al.  Metronome improves compression and ventilation rates during CPR on a manikin in a randomized trial. , 2010, Resuscitation.

[63]  E. Lerner,et al.  The Association between Emergency Medical Services Staffing Patterns and Out-of-Hospital Cardiac Arrest Survival , 2010, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

[64]  Kristy B Arbogast,et al.  Quantitative analysis of chest compression interruptions during in-hospital resuscitation of older children and adolescents. , 2009, Resuscitation.

[65]  Henry E. Wang,et al.  Interruptions in cardiopulmonary resuscitation from paramedic endotracheal intubation. , 2009, Annals of emergency medicine.

[66]  L. Wik,et al.  Advanced life support performance with manual and mechanical chest compressions in a randomized, multicentre manikin study. , 2009, Resuscitation.

[67]  Judy Powell,et al.  Chest Compression Fraction Determines Survival in Patients With Out-of-Hospital Ventricular Fibrillation , 2009, Circulation.

[68]  M. Bell,et al.  Sustaining Improvement in Door-to-Balloon Time Over 4 Years: The Mayo Clinic ST-Elevation Myocardial Infarction Protocol , 2009, Circulation. Cardiovascular quality and outcomes.

[69]  S. Manders,et al.  Alternating providers during continuous chest compressions for cardiac arrest: every minute or every two minutes? , 2009, Resuscitation.

[70]  B. Abella,et al.  Rescuer fatigue during actual in-hospital cardiopulmonary resuscitation with audiovisual feedback: a prospective multicenter study. , 2009, Resuscitation.

[71]  K. Roberts,et al.  "Rolling Refreshers": a novel approach to maintain CPR psychomotor skill competence. , 2009, Resuscitation.

[72]  R. Berg,et al.  Leaning is common during in-hospital pediatric CPR, and decreased with automated corrective feedback. , 2009, Resuscitation.

[73]  A. Noordergraaf,et al.  The impact of compliant surfaces on in-hospital chest compressions: effects of common mattresses and a backboard. , 2009, Resuscitation.

[74]  M. Boyle,et al.  Smaller self-inflating bags produce greater guideline consistent ventilation in simulated cardiopulmonary resuscitation , 2009, BMC emergency medicine.

[75]  Lisa M Bellini,et al.  Improving cardiopulmonary resuscitation quality and resuscitation training by combining audiovisual feedback and debriefing* , 2008, Critical care medicine.

[76]  A. Gurses,et al.  Systems ambiguity and guideline compliance: a qualitative study of how intensive care units follow evidence-based guidelines to reduce healthcare-associated infections , 2008, Quality & Safety in Health Care.

[77]  C. Callaway,et al.  Regional variation in out-of-hospital cardiac arrest incidence and outcome. , 2008, JAMA.

[78]  Raymond Y. W. Lee,et al.  Rescuer's position and energy consumption, spinal kinetics, and effectiveness of simulated cardiac compression. , 2008, American journal of critical care : an official publication, American Association of Critical-Care Nurses.

[79]  Karen Pierce,et al.  Evaluation of staff's retention of ACLS and BLS skills. , 2008, Resuscitation.

[80]  Charles F Babbs,et al.  A new paradigm for human resuscitation research using intelligent devices. , 2008, Resuscitation.

[81]  Benjamin S Abella,et al.  Improving in-hospital cardiac arrest process and outcomes with performance debriefing. , 2008, Archives of internal medicine.

[82]  A. Turpeinen,et al.  Quality of cardiopulmonary resuscitation on manikins: on the floor and in the bed , 2008, Acta anaesthesiologica Scandinavica.

[83]  J. Tibballs,et al.  Reliability of pulse palpation by healthcare personnel to diagnose paediatric cardiac arrest. , 2008, Resuscitation.

[84]  R. Berg,et al.  Minimally interrupted cardiac resuscitation by emergency medical services for out-of-hospital cardiac arrest. , 2008, JAMA.

[85]  J. Ornato,et al.  Survival from in-hospital cardiac arrest during nights and weekends. , 2008, JAMA.

[86]  P. Steen,et al.  Quality of cardiopulmonary resuscitation before and during transport in out-of-hospital cardiac arrest. , 2008, Resuscitation.

[87]  T. Aufderheide,et al.  Retention of CPR skills learned in a traditional AHA Heartsaver course versus 30-min video self-training: a controlled randomized study. , 2007, Resuscitation.

[88]  P. Pepe,et al.  Prospective, randomized trial of the effectiveness and retention of 30-min layperson training for cardiopulmonary resuscitation and automated external defibrillators: The American Airlines Study. , 2007, Resuscitation.

[89]  L. Rasmussen,et al.  Increasing compression depth during manikin CPR using a simple backboard , 2007, Acta anaesthesiologica Scandinavica.

[90]  F. Sterz,et al.  Quality of closed chest compression in ambulance vehicles, flying helicopters and at the scene. , 2007, Resuscitation.

[91]  C. Deakin,et al.  Do we hyperventilate cardiac arrest patients? , 2007, Resuscitation.

[92]  Gavin D Perkins,et al.  The impact of manual defibrillation technique on no-flow time during simulated cardiopulmonary resuscitation. , 2007, Resuscitation.

[93]  Karl B Kern,et al.  Advanced cardiac life support training improves long-term survival from in-hospital cardiac arrest. , 2007, Resuscitation.

[94]  T. Rea,et al.  Increasing Use of Cardiopulmonary Resuscitation During Out-of-Hospital Ventricular Fibrillation Arrest: Survival Implications of Guideline Changes , 2006, Circulation.

[95]  Jo Kramer-Johansen,et al.  Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study. , 2006, Resuscitation.

[96]  Jo Kramer-Johansen,et al.  Effects of compression depth and pre-shock pauses predict defibrillation failure during cardiac arrest. , 2006, Resuscitation.

[97]  T. Terndrup,et al.  Available ventilation monitoring methods during pre-hospital cardiopulmonary resuscitation. , 2006, Resuscitation.

[98]  L. Svensson,et al.  Clinical consequences of the introduction of mechanical chest compression in the EMS system for treatment of out-of-hospital cardiac arrest-a pilot study. , 2006, Resuscitation.

[99]  G. Perkins,et al.  Effects of a backboard, bed height, and operator position on compression depth during simulated resuscitation , 2006, Intensive Care Medicine.

[100]  T. Rea,et al.  Manual chest compression vs use of an automated chest compression device during resuscitation following out-of-hospital cardiac arrest: a randomized trial. , 2006, JAMA.

[101]  Robert A. Berg,et al.  Interruptions of Chest Compressions During Emergency Medical Systems Resuscitation , 2005, Circulation.

[102]  P. Steen,et al.  Twelve-month retention of CPR skills with automatic correcting verbal feedback. , 2005, Resuscitation.

[103]  S. Rubertsson,et al.  Increased cortical cerebral blood flow with LUCAS; a new device for mechanical chest compressions compared to standard external compressions during experimental cardiopulmonary resuscitation. , 2005, Resuscitation.

[104]  T. Aufderheide,et al.  Incomplete chest wall decompression: a clinical evaluation of CPR performance by EMS personnel and assessment of alternative manual chest compression-decompression techniques. , 2005, Resuscitation.

[105]  T. Aufderheide,et al.  Effects of incomplete chest wall decompression during cardiopulmonary resuscitation on coronary and cerebral perfusion pressures in a porcine model of cardiac arrest. , 2005, Resuscitation.

[106]  B. Abella,et al.  Chest Compression Rates During Cardiopulmonary Resuscitation Are Suboptimal: A Prospective Study During In-Hospital Cardiac Arrest , 2005, Circulation.

[107]  P. Steen,et al.  Quality of cardiopulmonary resuscitation during out-of-hospital cardiac arrest. , 2005, JAMA.

[108]  J. Catineau,et al.  Basic cardiac life support providers checking the carotid pulse: performance, degree of conviction, and influencing factors. , 2004, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[109]  H. Halperin,et al.  Improved hemodynamic performance with a novel chest compression device during treatment of in-hospital cardiac arrest. , 2004, Resuscitation.

[110]  Tom P. Aufderheide,et al.  Hyperventilation-Induced Hypotension During Cardiopulmonary Resuscitation , 2004, Circulation.

[111]  P. Steen,et al.  Oxygen delivery and return of spontaneous circulation with ventilation:compression ratio 2:30 versus chest compressions only CPR in pigs. , 2004, Resuscitation.

[112]  A. Keenan,et al.  Effect of rescuer fatigue on performance of continuous external chest compressions over 3 min. , 2002, Resuscitation.

[113]  Lars Wik,et al.  Retention of basic life support skills 6 months after training with an automated voice advisory manikin system without instructor involvement. , 2002, Resuscitation.

[114]  M. Sihvonen,et al.  Cardiopulmonary resuscitation skills in nurses and nursing students. , 2000, Resuscitation.

[115]  M. Durham,et al.  In-hospital resuscitation: association between ACLS training and survival to discharge. , 2000, Resuscitation.

[116]  P. Steen,et al.  Arterial blood-gases with 500- versus 1000-ml tidal volumes during out-of-hospital CPR. , 2000, Resuscitation.

[117]  M. Copass,et al.  Cardiopulmonary resuscitation by chest compression alone or with mouth-to-mouth ventilation. , 2000, The New England journal of medicine.

[118]  P. Moule,et al.  Checking the carotid pulse: diagnostic accuracy in students of the healthcare professions. , 2000, Resuscitation.

[119]  C. Keller,et al.  Effects of smaller tidal volumes during basic life support ventilation in patients with respiratory arrest: good ventilation, less risk? , 1999, Resuscitation.

[120]  R. Woda,et al.  The ventilatory effects of auto-positive end-expiratory pressure development during cardiopulmonary resuscitation. , 1999, Critical care medicine.

[121]  R. Berg,et al.  Simulated mouth-to-mouth ventilation and chest compressions (bystander cardiopulmonary resuscitation) improves outcome in a swine model of prehospital pediatric asphyxial cardiac arrest. , 1999, Critical care medicine.

[122]  S. Cooper,et al.  Leadership of resuscitation teams: "Lighthouse Leadership'. , 1999, Resuscitation.

[123]  F J Ochoa,et al.  Competence of health professionals to check the carotid pulse. , 1998, Resuscitation.

[124]  F J Ochoa,et al.  The effect of rescuer fatigue on the quality of chest compressions. , 1998, Resuscitation.

[125]  R. Salluzzo,et al.  Effectiveness of mechanical versus manual chest compressions in out-of-hospital cardiac arrest resuscitation: a pilot study. , 1998, The American journal of emergency medicine.

[126]  R. Berg,et al.  Assisted ventilation during 'bystander' CPR in a swine acute myocardial infarction model does not improve outcome. , 1997, Circulation.

[127]  W Panzer,et al.  Skills of lay people in checking the carotid pulse. , 1997, Resuscitation.

[128]  C. Miller,et al.  End-tidal carbon dioxide and outcome of out-of-hospital cardiac arrest. , 1997, The New England journal of medicine.

[129]  P. Steen,et al.  Quality of mechanical, manual standard and active compression-decompression CPR on the arrest site and during transport in a manikin model. , 1997, Resuscitation.

[130]  W. Dick,et al.  Checking the carotid pulse check: diagnostic accuracy of first responders in patients with and without a pulse. , 1996, Resuscitation.

[131]  S. O'kelly,et al.  The palpation of pulses. , 1996, Anaesthesia.

[132]  P. Duvaldestin,et al.  End-tidal carbon dioxide during cardiopulmonary resuscitation in humans presenting mostly with asystole: a predictor of outcome. , 1996, Critical care medicine.

[133]  S. Thomas,et al.  Decay in quality of closed-chest compressions over time. , 1995, Annals of emergency medicine.

[134]  G A Ewy,et al.  Chest compression and ventilation rates during cardiopulmonary resuscitation: the effects of audible tone guidance. , 1995, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[135]  M. Georgieff,et al.  Vasopressin improves vital organ blood flow during closed-chest cardiopulmonary resuscitation in pigs. , 1995, Circulation.

[136]  J. Ornato,et al.  Relationship between cardiac output and the end-tidal carbon dioxide tension. , 1990, Annals of emergency medicine.

[137]  T. J. Appleton,et al.  Coronary perfusion pressure and the return of spontaneous circulation in human cardiopulmonary resuscitation. , 1990, JAMA.

[138]  C W Otto,et al.  End-Tidal Carbon Dioxide Monitoring During Cardiopulmonary Resuscitation: A Prognostic Indicator for Survival , 1989 .

[139]  G A Ewy,et al.  Myocardial perfusion pressure: a predictor of 24-hour survival during prolonged cardiac arrest in dogs. , 1988, Resuscitation.

[140]  H. Halperin,et al.  Determinants of blood flow to vital organs during cardiopulmonary resuscitation in dogs. , 1986, Circulation.

[141]  R. Nowak,et al.  Aortic and right atrial pressures during standard and simultaneous compression and ventilation CPR in human beings. , 1986, Annals of emergency medicine.

[142]  M. Weil,et al.  Cardiac output and end‐tidal carbon dioxide , 1985, Critical care medicine.

[143]  M. C. Rogers,et al.  Mechanisms by which epinephrine augments cerebral and myocardial perfusion during cardiopulmonary resuscitation in dogs. , 1984, Circulation.

[144]  C. Babbs,et al.  Intrapulmonary epinephrine during prolonged cardiopulmonary resuscitation: improved regional blood flow and resuscitation in dogs. , 1984, Annals of emergency medicine.

[145]  J. Rosborough,et al.  Coronary perfusion pressure during experimental cardiopulmonary resuscitation. , 1982, Annals of emergency medicine.

[146]  M. K. Sykes,et al.  THE EFFECTS OF VARIATIONS IN END‐EXPIRATORY INFLATION PRESSURE ON CARDIORESPIRATORY FUNCTION IN NORMO-, HYPO- AND HYPERVOLAEMIC DOGS , 1972, British journal of anaesthesia.

[147]  J. Pearson,et al.  Resuscitation from ventricular fibrillation. Drug therapy. , 1968, JAMA.

[148]  J. Pearson,et al.  Peripheral vascular tone on cardiac resuscitation. , 1965, Anesthesia and analgesia.

[149]  C. Beck,et al.  Death after a clean bill of health. So-called "fatal" heart attacks and treatment with resucitation techniques. , 1960, JAMA.

[150]  A. Cournand,et al.  Physiological studies of the effects of intermittent positive pressure breathing on cardiac output in man. , 1947, The American journal of physiology.

[151]  G. Crile,et al.  AN EXPERIMENTAL RESEARCH INTO THE RESUSCITATION OF DOGS KILLED BY ANESTHETICS AND ASPHYXIA , 1906, The Journal of experimental medicine.

[152]  Yongqin Li,et al.  An Algorithm Used for Ventricular Fibrillation Detection Without Interrupting Chest Compression , 2012, IEEE Transactions on Biomedical Engineering.

[153]  Hans-Rüdiger Pfister,et al.  – a simulator study , 2011 .

[154]  北村 哲久 Conventional and chest-compression-only cardiopulmonary resuscitation by bystanders for children who have out-of-hospital cardiac arrests : a prospective, nationwide, population-based cohort study , 2011 .

[155]  S. Trzeciak Survival From In-Hospital Cardiac Arrest During Nights and Weekends , 2009 .

[156]  Fong-Chin Su,et al.  Effects of rescuer position on the kinematics of cardiopulmonary resuscitation (CPR) and the force of delivered compressions. , 2008, Resuscitation.

[157]  B. Abella,et al.  Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. , 2005, JAMA.

[158]  L. Bossaert,et al.  Quality and efficiency of bystander CPR. Belgian Cerebral Resuscitation Study Group. , 1993, Resuscitation.

[159]  G. Ewy,et al.  Coronary perfusion pressure during cardiopulmonary resuscitation. , 1985, The American journal of emergency medicine.

[160]  P E Pepe,et al.  Occult positive end-expiratory pressure in mechanically ventilated patients with airflow obstruction: the auto-PEEP effect. , 1982, The American review of respiratory disease.

[161]  G. Duvel The study group. , 1980 .