A Thyroid-Stimulating Life: An Interview with Dr. J. Maxwell McKenzie

BEST KNOWN to the thyroid world for the introduction of the McKenzie bioassay for thyroid-stimulating antibodies (see Box), Dr. Maxwell McKenzie has had a long and distinguished career in thyroid research and internal medicine. He retired after 13 years as chairman of medicine at the University of Miami in 1994 and continues to contribute to his department and university. I persuaded Dr. McKenzie to spend some time with me in Palm Beach to talk about old times and the following is a relatively uncensored record of our conversation. Modest and retiring, Max McKenzie has much to teach us all and I have included some key references which should be read in conjunction with this transcript. This report, along with a previous interview with Dr. Robert Volpe (1), is part of an ongoing series we would like to see continued in Thyroid.

[1]  J. Mckenzie.  Neonatal Graves Disease , 2020, Definitions.

[2]  T. Davies.  GROWING AN INTEREST IN AUTOIMMUNE THYROID DISEASE: An Interview with Robert Volpé, MD, FRCP(C) , 2000 .

[3]  G. Kahaly,et al.  Glycosaminoglycans in thyroid eye disease. , 1998, Thyroid : official journal of the American Thyroid Association.

[4]  J. Mckenzie,et al.  35S-sulfate uptake by mouse harderian gland: Effect of serum from patients with Graves' disease , 1971 .

[5]  J. McKenzie,et al.  Studies of homologous immunization with mouse harderian gland. , 1971, Metabolism: clinical and experimental.

[6]  J. McKenzie,et al.  The Influence of Thyrotropin on Harderian Gland Glycosaminoglycans of the Mouse 1 , 1970, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[7]  J. Mckenzie,et al.  Effect of thyrotropin on thyroid pyridine nucleotides in vitro. , 1969, Endocrinology.

[8]  J. Mckenzie.  Experimental production of a thyroid-stimulating antithyroid antibody. , 1968, The Journal of clinical endocrinology and metabolism.

[9]  J. Kriss,et al.  ISOLATION AND IDENTIFICATION OF THE LONG-ACTING THYROID STIMULATOR AND ITS RELATION TO HYPERTHYROIDISM AND CIRCUMSCRIBED PRETIBIAL MYXEDEMA. , 1964, The Journal of clinical endocrinology and metabolism.

[10]  G. K. Smelser.  Experimental studies on exophthalmos. , 1962, American journal of ophthalmology.

[11]  Mckenzie Jm.  Fractionation of plasma containing the long acting thyroid stimulator. , 1962 .

[12]  Mckenzie Jm.  Delayed thyroid response to serum from thyrotoxic patients. , 1958 .

[13]  D. Doniach,et al.  Auto-antibodies in Hashimoto's disease (lymphadenoid goitre). , 1956, Lancet.

[14]  N. Rose,et al.  Studies on organ specificity. V. Changes in the thyroid glands of rabbits following active immunization with rabbit thyroid extracts. , 1956, Journal of immunology.